(Q39571989)

English

Enhanced anti-tumor activity and safety profile of targeted nano-scaled HPMA copolymer-alendronate-TNP-470 conjugate in the treatment of bone malignances

scientific article published on 22 March 2011

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Enhanced anti-tumor activity and safety profile of targeted nano-scaled HPMA copolymer-alendronate-TNP-470 conjugate in the treatment of bone malignances (English)

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

1 reference

based on heuristic

inferred from title

Ronit Satchi-Fainaro

object named as

Ronit Satchi-Fainaro

7

0 references

author name string

Ehud Segal

1

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Huaizhong Pan

2

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Liat Benayoun

3

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Pavla Kopečková

4

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Yuval Shaked

5

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Jindřich Kopeček

6

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

publication date

22 March 2011

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

32

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

19

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

4450-4463

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Optimizing ixabepilone treatment schedules in patients with advanced or metastatic breast cancer

1 reference

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Identification of optimal drug combinations targeting cellular networks: integrating phospho-proteomics and computational network analysis

1 reference

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Targeting of drugs and nanoparticles to tumors

1 reference

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Rapid pharmacokinetic and biodistribution studies using cholorotoxin-conjugated iron oxide nanoparticles: a novel non-radioactive method

1 reference

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Evading tumor evasion: current concepts and perspectives of anti-angiogenic cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

14 September 2017

HPMA copolymers: origins, early developments, present, and future

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

14 September 2017

Design and development of polymer conjugates as anti-angiogenic agents

1 reference

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Adverse effects of bisphosphonates: implications for osteoporosis management

1 reference

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The multiple personality disorder phenotype(s) of circulating endothelial cells in cancer

1 reference

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Targeting angiogenesis-dependent calcified neoplasms using combined polymer therapeutics

1 reference

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Mouse xenograft models vs GEM models for human cancer therapeutics

1 reference

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Feasibility of using a bone-targeted, macromolecular delivery system coupled with prostaglandin E(1) to promote bone formation in aged, estrogen-deficient rats

1 reference

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14 September 2017

Biodistribution and pharmacokinetic studies of bone-targeting N-(2-hydroxypropyl)methacrylamide copolymer-alendronate conjugates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

14 September 2017

Emerging role of bisphosphonates in the clinic--antitumor activity and prevention of metastasis to bone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

14 September 2017

Biology of bone metastases: causes and consequences.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

14 September 2017

Angiogenesis: an organizing principle for drug discovery?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

14 September 2017

Murine models to evaluate novel and conventional therapeutic strategies for cancer

1 reference

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14 September 2017

Markers of angiogenesis and clinical features in patients with sarcoma

1 reference

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14 September 2017

Molecular pathogenesis of osteosarcoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

14 September 2017

Anti-angiogenic therapy for osteosarcoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

14 September 2017

Polymer conjugates as anticancer nanomedicines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

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Barriers to efficient development of cancer therapeutics

1 reference

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14 September 2017

Emerging anti-cancer molecular mechanisms of aminobisphosphonates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

14 September 2017

Circulating endothelial-cell kinetics and viability predict survival in breast cancer patients receiving metronomic chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

14 September 2017

Polymer therapeutics: concepts and applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

14 September 2017

Cellular and molecular surrogate markers to monitor targeted and non-targeted antiangiogenic drug activity and determine optimal biologic dose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

14 September 2017

Designing proteins for bone targeting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

14 September 2017

Inhibition of vessel permeability by TNP-470 and its polymer conjugate, caplostatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

14 September 2017

Endogenous angiogenesis inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

14 September 2017

An amino-bisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

14 September 2017

Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer

1 reference

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14 September 2017

Animal models of tumor immunity, immunotherapy and cancer vaccines

1 reference

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14 September 2017

Tissue factor and angiogenesis in cancer

1 reference

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14 September 2017

Primer for non-immunologists on immune-deficient mice and their applications in research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

14 September 2017

Bisphosphonates in bone diseases other than osteoporosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

14 September 2017

TNP-470: an angiogenesis inhibitor in clinical development for cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

14 September 2017

The role of bisphosphonates in metastatic breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

14 September 2017

The relationship between angiogenesis and the immune response in carcinogenesis and the progression of malignant disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

14 September 2017

Chemotherapy-induced anemia in adults: incidence and treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

14 September 2017

Bisphosphonates in the treatment of malignant bone disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

14 September 2017

Molecular cloning of human cDNA for cathepsin K: novel cysteine proteinase predominantly expressed in bone

1 reference

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Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth

1 reference

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Real-time monitoring of drug release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

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Zoledronic acid inhibits osteosarcoma growth in an orthotopic model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

14 September 2017

Cathepsins and osteosarcoma: Expression analysis identifies cathepsin K as an indicator of metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

14 September 2017

Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

14 September 2017

Alendronate inhibits intraperitoneal dissemination in in vivo ovarian cancer model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

14 September 2017

Sustained response to intravenous alendronate in postmenopausal osteoporosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

14 September 2017

An orthotopic model of murine osteosarcoma with clonally related variants differing in pulmonary metastatic potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

25 September 2017

Role of cytokines in the regulation of bone resorption

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

25 September 2017

Targetable HPMA copolymer-adriamycin conjugates. Recognition, internalization, and subcellular fate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

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Skeletal complications of malignancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

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Subdural collections arising from calvarial metastases following discontinuation of anti-angiogenic therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

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The level of vascular endothelial growth factor as a predictor of a poor prognosis in osteosarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

21 August 2018

Targeting bone metastases with a bispecific anticancer and antiangiogenic polymer-alendronate-taxane conjugate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

21 August 2018

Metronomic cyclophosphamide and capecitabine combined with bevacizumab in advanced breast cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

21 August 2018

Osteosarcoma: the same old drugs or more?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

21 August 2018

A surrogate marker to monitor angiogenesis at last

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

21 August 2018

The arthrotropism of macromolecules in adjuvant-induced arthritis rat model: a preliminary study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

21 August 2018

Facile, controlled, room-temperature RAFT polymerization of N-isopropylacrylamide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

21 August 2018

Targeting angiogenesis with a conjugate of HPMA copolymer and TNP-470.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

21 August 2018

Synthesis and evaluation of water-soluble polymeric bone-targeted drug delivery systems.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

21 August 2018

Spectrophotometric determination of alendronate in pharmaceutical formulations via complex formation with Fe(III) ions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

21 August 2018

Preclinical evaluation of the cardiotoxicity of PK2: a novel HPMA copolymer-doxorubicin-galactosamine conjugate antitumour agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

21 August 2018

A Phase I and pharmacokinetic study of TNP-470 administered weekly to patients with advanced cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598046

2 December 2018

Arrest of human lung tumor xenograft growth in severe combined immunodeficient mice using doxorubicin encapsulated in sterically stabilized liposomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21429572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biocompatibility of N-(2-hydroxypropyl) methacrylamide copolymers containing adriamycin. Immunogenicity, and effect on haematopoietic stem cells in bone marrow in vivo and mouse splenocytes and human peripheral blood lymphocytes in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/21429572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toxicity of bisphosphonates

1 reference

https://pubmed.ncbi.nlm.nih.gov/21429572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Polymer-Triton X-100 Conjugate Capable of PH-Dependent Red Blood Cell Lysis: A Model System Illustrating the Possibility of Drug Delivery Within Acidic Intracellular Compartments

1 reference

https://pubmed.ncbi.nlm.nih.gov/21429572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapy: Bisphosphonate users: cancer risk

1 reference

https://pubmed.ncbi.nlm.nih.gov/21429572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteoporosis, fracture risk, and prosthodontic implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/21429572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic heterogeneity of the vasculogenic phenotype parallels angiogenesis; Implications for cellular surrogate marker analysis of antiangiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21429572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteotropic Peptide that differentiates functional domains of the skeleton

1 reference

https://pubmed.ncbi.nlm.nih.gov/21429572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Water-soluble HPMA copolymer--prostaglandin E1 conjugates containing a cathepsin K sensitive spacer

1 reference

https://pubmed.ncbi.nlm.nih.gov/21429572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of alendronate on cytokine production, adhesion molecule expression, and transendothelial migration of human peripheral blood mononuclear cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21429572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell-retained isoforms of vascular endothelial growth factor (VEGF) are correlated with poor prognosis in osteosarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21429572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.BIOMATERIALS.2011.02.059

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

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