(Q39572385)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426304%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

Clioquinol induces cytoplasmic clearance of the X-linked inhibitor of apoptosis protein (XIAP): therapeutic indication for prostate cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426304%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

ChEBI release 2020-05-28

ChEBI ID

74460

therapeutic indication

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426304%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

author name string

Michael A Cater

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426304%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

language of work or name

English

0 references

publication date

1 June 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426304%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

number of pages

11

1 reference

based on heuristic

inferred from page(s)

published in

Biochemical Journal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426304%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

volume

436

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426304%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426304%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

page(s)

481-491

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426304%20AND%20SRC:MED&resulttype=core&format=json

Phase I study of copper-binding agent ATN-224 in patients with advanced solid tumors

26 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

Elevated copper and oxidative stress in cancer cells as a target for cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

Levels of selenium, zinc, copper, and antioxidant enzyme activity in patients with leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

Copper and carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

Clioquinol inhibits the proteasome and displays preclinical activity in leukemia and myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

Clioquinol and docosahexaenoic acid act synergistically to kill tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

The toxicology of Clioquinol

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

Clioquinol and pyrithione activate TRPA1 by increasing intracellular Zn2+.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

Tumor cellular proteasome inhibition and growth suppression by 8-hydroxyquinoline and clioquinol requires their capabilities to bind copper and transport copper into cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

Clioquinol, a therapeutic agent for Alzheimer's disease, has proteasome-inhibitory, androgen receptor-suppressing, apoptosis-inducing, and antitumor activities in human prostate cancer cells and xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

Novel dipeptidyl proteasome inhibitors overcome Bcl-2 protective function and selectively accumulate the cyclin-dependent kinase inhibitor p27 and induce apoptosis in transformed, but not normal, human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

IAPs as a target for anticancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

IAP family proteins--suppressors of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

Reprieval from execution: the molecular basis of caspase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

IAP family protein expression correlates with poor outcome of multiple myeloma patients in association with chemotherapy-induced overexpression of multidrug resistance genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

Inhibitors of apoptosis proteins (IAPs) expression and their prognostic significance in hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

Prognostic significance of XIAP expression in DLBCL and effect of its inhibition on AKT signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

Preclinical characterization of AEG35156/GEM 640, a second-generation antisense oligonucleotide targeting X-linked inhibitor of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

Regulation of the copper chaperone CCS by XIAP-mediated ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

XIAP Is a copper binding protein deregulated in Wilson's disease and other copper toxicosis disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

A novel role for XIAP in copper homeostasis through regulation of MURR1

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

Uncoupling of the signaling and caspase-inhibitory properties of X-linked inhibitor of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

Syntaxin 5 is required for copper homeostasis in Drosophila and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

The zinc and copper content of blood leucocytes and plasma from patients with benign and malignant prostates

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

Proteins associated with the promyelocytic leukemia gene product (PML)-containing nuclear body move to the nucleolus upon inhibition of proteasome-dependent protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

21 January 2018

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

Cadmium down-regulates expression of XIAP at the post-transcriptional level in prostate cancer cells through an NF-kappaB-independent, proteasome-mediated mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

Zinc chelation induces rapid depletion of the X-linked inhibitor of apoptosis and sensitizes prostate cancer cells to TRAIL-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

Proteasome inhibition by MG-132 induces apoptotic cell death and mitochondrial dysfunction in cultured rat brain oligodendrocytes but not in astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

Clioquinol targets zinc to lysosomes in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110123

21 January 2018

Identifiers

DOI

10.1042/BJ20110123

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426304%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference