(Q48586917)

English

Proteasome inhibition by MG-132 induces apoptotic cell death and mitochondrial dysfunction in cultured rat brain oligodendrocytes but not in astrocytes.

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scholarly article

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16609961

Proteasome inhibition by MG-132 induces apoptotic cell death and mitochondrial dysfunction in cultured rat brain oligodendrocytes but not in astrocytes. (English)

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16609961

apoptotic process

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oligodendrocyte

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inferred from title

Christiane Richter-Landsberg

3

object named as

Christiane Richter-Landsberg

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Europe PubMed Central

13 February 2018

1

object named as

Olaf Goldbaum

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Europe PubMed Central

13 February 2018

author name string

Grit Vollmer

2

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Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16609961

publication date

1 June 2006

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Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16609961

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16609961

53

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Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16609961

8

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Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16609961

891-901

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Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16609961

Global impairment of the ubiquitin-proteasome system by nuclear or cytoplasmic protein aggregates precedes inclusion body formation.

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Pathological glial tau accumulations in neurodegenerative disease: review and case report

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Glial inclusions in CNS degenerative diseases.

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The ubiquitin proteasome system in neurodegenerative diseases: sometimes the chicken, sometimes the egg.

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Relationship of iron to oligodendrocytes and myelination

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Regulation and role of heme oxygenase in oxidative injury

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Proteasome inhibition in oxidative stress neurotoxicity: implications for heat shock proteins.

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Peroxide detoxification by brain cells.

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Heme oxygenase: recent advances in understanding its regulation and role.

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Cooperation of molecular chaperones with the ubiquitin/proteasome system

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Oxidants, oxidative stress and the biology of ageing

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Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family

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Iron in CNS disease.

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The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's diseases

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Differential regulation of bcl-2, bax, c-fos, junB, and krox-24 expression in the cerebellum of Purkinje cell degeneration mutant mice

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Filamentous nerve cell inclusions in neurodegenerative diseases

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Stress proteins in oligodendrocytes: differential effects of heat shock and oxidative stress

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Activation of PP2A-like phosphatase and modulation of tau phosphorylation accompany stress-induced apoptosis in cultured oligodendrocytes

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Proteolytic stress causes heat shock protein induction, tau ubiquitination, and the recruitment of ubiquitin to tau-positive aggregates in oligodendrocytes in culture.

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Selective degeneration of oligodendrocytes mediated by reactive oxygen species.

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Hypothesis: proteasomal dysfunction: a primary event in neurogeneration that leads to nitrative and oxidative stress and subsequent cell death

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Oligodendroglial precursor cell susceptibility to hypoxia is related to poor ability to cope with reactive oxygen species

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The proteasome in brain aging

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Impaired proteasome function in Alzheimer's disease

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Decreased levels of proteasome activity and proteasome expression in aging spinal cord

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Proteasome inhibitors induce mitochondria-independent apoptosis in human glioma cells

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Tau-positive glial inclusions in progressive supranuclear palsy, corticobasal degeneration and Pick's disease

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Sensitivity of proteasome to its inhibitors increases during cAMP-induced differentiation of neuroblastoma cells in culture and causes decreased viability

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Application of proteasomal inhibitors to mouse sympathetic neurons activates the intrinsic apoptotic pathway

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Role of ubiquitin-mediated proteolysis in the pathogenesis of neurodegenerative disorders.

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Expression of biochemical properties of oligodendrocytes in oligodendrocyte x glioma cell hybrids proliferating in vitro.

1 reference

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Mitochondrial pathway is involved in hydrogen-peroxide-induced apoptotic cell death of oligodendrocytes.

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The oligodendrocyte and its many cellular processes

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Proteasome inhibitors induce cytochrome c-caspase-3-like protease-mediated apoptosis in cultured cortical neurons.

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Organization and functional roles of the cytoskeleton in oligodendrocytes

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Stress proteins in neural cells: functional roles in health and disease

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Mode of cell injury and death after hydrogen peroxide exposure in cultured oligodendroglia cells.

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Role of mitochondria in toxic cell death

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Heme oxygenase-1: transducer of pathological brain iron sequestration under oxidative stress

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Poly(ADP-ribose) polymerase-1 cleavage during apoptosis: an update

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Over-expression of heme oxygenase-1 promotes oxidative mitochondrial damage in rat astroglia

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Proteasome inhibition alters neural mitochondrial homeostasis and mitochondria turnover

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The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet.

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Proteasome inhibitor-induced apoptosis of glioma cells involves the processing of multiple caspases and cytochrome c release.

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Identifiers

10.1002/GLIA.20348

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16609961

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16609961

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