(Q35548597)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14522239%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

review article

1 reference

title

Role of ubiquitin-mediated proteolysis in the pathogenesis of neurodegenerative disorders (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14522239%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14522239%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

0 references

James R Cavey

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14522239%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

James Lowe

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14522239%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

language of work or name

1 reference

1 October 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14522239%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

published in

Ageing Research Reviews

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14522239%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

volume

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14522239%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14522239%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

page(s)

343-356

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14522239%20AND%20SRC:MED&resulttype=core&format=json

Ubiquitin: not just for proteasomes anymore

19 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

In vivo disassembly of free polyubiquitin chains by yeast Ubp14 modulates rates of protein degradation by the proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Accumulation of abnormally phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Impairment of the ubiquitin-proteasome system by protein aggregation

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Proteasomal degradation of tau protein

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Mutant ubiquitin expressed in Alzheimer's disease causes neuronal death.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Activity level controls postsynaptic composition and signaling via the ubiquitin-proteasome system

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Pathological lesions of Alzheimer's disease and dementia with Lewy bodies brains exhibit immunoreactivity to an ATPase that is a regulatory subunit of the 26S proteasome.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Neurofibrillary tangles in progressive supranuclear palsy brains exhibit immunoreactivity to frameshift mutant ubiquitin-B protein

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Identification of genes that modify ataxin-1-induced neurodegeneration.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Ubiquitin lys63 is involved in ubiquitination of a yeast plasma membrane protein

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Tau protein and the neurofibrillary pathology of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Tau mutations cause frontotemporal dementias.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

alpha-Synuclein immunoreactivity in dementia with Lewy bodies: morphological staging and comparison with ubiquitin immunostaining

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Amyloid beta-protein inhibits ubiquitin-dependent protein degradation in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Phosphorylated alpha-synuclein is ubiquitinated in alpha-synucleinopathy lesions

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Human recombinant NACP/alpha-synuclein is aggregated and fibrillated in vitro: relevance for Lewy body disease

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Spongiform degeneration in mahoganoid mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Ubiquitin and the synapse.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

1 reference

7 January 2021

Immunocytochemical co-localization of the proteasome in ubiquitinated structures in neurodegenerative diseases and the elderly.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

A proteolytic pathway that recognizes ubiquitin as a degradation signal

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Proteasome inhibition by paired helical filament-tau in brains of patients with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Impaired proteasome function in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

UBE3A/E6-AP mutations cause Angelman syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Multicatalytic proteinase is present in Lewy bodies and neurofibrillary tangles in diffuse Lewy body disease brains.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Inhibition of the ubiquitin-proteasome system in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

A proteasomal ATPase subunit recognizes the polyubiquitin degradation signal

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Does an inhibition of the ubiquitin/26S proteasome pathway of protein degradation underlie the pathogenesis of non-familial Alzheimer's disease?

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

The ubiquitin protein catabolic disorders.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Characterization of cytoplasmic alpha-synuclein aggregates. Fibril formation is tightly linked to the inclusion-forming process in cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Neurodegenerative tauopathies

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

The ubiquitin pathway in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Mutant ubiquitin found in neurodegenerative disorders is a ubiquitin fusion degradation substrate that blocks proteasomal degradation

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Endoproteolytic activity of the proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Defective ubiquitination of cerebral proteins in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Ubiquitin is a common factor in intermediate filament inclusion bodies of diverse type in man, including those of Parkinson's disease, Pick's disease, and Alzheimer's disease, as well as Rosenthal fibres in cerebellar astrocytomas, cytoplasmic bodie

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

A filamentous inclusion body within anterior horn neurones in motor neurone disease defined by immunocytochemical localisation of ubiquitin

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Quality control of mRNA function

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Proteasomal-dependent aggregate reversal and absence of cell death in a conditional mouse model of Huntington's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

De novo truncating mutations in E6-AP ubiquitin-protein ligase gene (UBE3A) in Angelman syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Alpha-synuclein-enhanced green fluorescent protein fusion proteins form proteasome sensitive inclusions in primary neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Proteasomal function is impaired in substantia nigra in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Selective loss of 20S proteasome alpha-subunits in the substantia nigra pars compacta in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Impairment of the ubiquitin-proteasome system causes dopaminergic cell death and inclusion body formation in ventral mesencephalic cultures

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Altered proteasomal function in sporadic Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Ubiquitin is a component of paired helical filaments in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Ubiquitin is conjugated with amino-terminally processed tau in paired helical filaments

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

How the ubiquitin-proteasome system controls transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Proteins are unfolded on the surface of the ATPase ring before transport into the proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Proteasomal inhibition leads to formation of ubiquitin/alpha-synuclein-immunoreactive inclusions in PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad mice

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Aggregated and monomeric alpha-synuclein bind to the S6' proteasomal protein and inhibit proteasomal function

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

A ubiquitin mutant with specific defects in DNA repair and multiubiquitination

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Alpha-synuclein in Lewy bodies

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Expression of mutant alpha-synuclein causes increased susceptibility to dopamine toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Aggresomes protect cells by enhancing the degradation of toxic polyglutamine-containing protein

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Recognition of the polyubiquitin proteolytic signal

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

alpha-synuclein metabolism and aggregation is linked to ubiquitin-independent degradation by the proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Parkin facilitates the elimination of expanded polyglutamine proteins and leads to preservation of proteasome function.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Clinical and pathologic abnormalities in a family with parkinsonism and parkin gene mutations.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Frameshift mutants of beta amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

+1 Proteins and aging

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Ubiquitination and deubiquitination: targeting of proteins for degradation by the proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Synaptic defects in ataxia mice result from a mutation in Usp14, encoding a ubiquitin-specific protease

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900025-4

7 January 2021

10.1016/S1568-1637(03)00025-4

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14522239%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

1 reference