(Q39581641)

13 September 2017

title

Alzheimer disease-related presenilin-1 variants exert distinct effects on monoamine oxidase-A activity in vitro (English)

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13 September 2017

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Paul R Pennington

1

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13 September 2017

Zelan Wei

2

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13 September 2017

Lewei Rui

3

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13 September 2017

Jennifer A Doig

4

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13 September 2017

Brett Graham

5

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13 September 2017

Kelly Kuski

6

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13 September 2017

Geraldine G Gabriel

7

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13 September 2017

Darrell D Mousseau

8

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13 September 2017

publication date

4 March 2011

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Journal of Neural Transmission

13 September 2017

published in

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13 September 2017

volume

118

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13 September 2017

issue

7

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13 September 2017

page(s)

987-995

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Earlier psychiatric morbidity in patients with Alzheimer's disease.

13 September 2017

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Changes of Biogenic Amines and Their Metabolites in Postmortem Brains from Patients with Alzheimer-Type Dementia

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Neurotoxicity of MAO metabolites of catecholamine neurotransmitters: role in neurodegenerative diseases

21 January 2018

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Calcium-sensitive regulation of monoamine oxidase-A contributes to the production of peroxyradicals in hippocampal cultures: implications for Alzheimer disease-related pathology

21 January 2018

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Calcium alters monoamine oxidase-A parameters in human cerebellar and rat glial C6 cell extracts: possible influence by distinct signalling pathways

21 January 2018

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Serine 209 resides within a putative p38(MAPK) consensus motif and regulates monoamine oxidase-A activity

21 January 2018

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Presenilin-1 differentially facilitates endoproteolysis of the beta-amyloid precursor protein and Notch

21 January 2018

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Depression and Alzheimer's disease: neurobiological links and common pharmacological targets

21 January 2018

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Depression and senile dementia of the Alzheimer type: a role for moclobemide

21 January 2018

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21 January 2018

12 December 2020

History of depression, depressive symptoms, and medial temporal lobe atrophy and the risk of Alzheimer disease.

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Locus coeruleus neurofibrillary degeneration in aging, mild cognitive impairment and early Alzheimer's disease

21 January 2018

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Oxidative stress related markers in the "VITA" and the centenarian projects.

21 January 2018

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Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice

21 January 2018

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Nicastrin, presenilin, APH-1, and PEN-2 form active gamma-secretase complexes in mitochondria

21 January 2018

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Dimerization of presenilin-1 in vivo: suggestion of novel regulatory mechanisms leading to higher order complexes

21 January 2018

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Distribution of Alzheimer's neurofibrillary changes in the brain stem and hypothalamus of senile dementia

21 January 2018

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Presenilins mediate phosphatidylinositol 3-kinase/AKT and ERK activation via select signaling receptors. Selectivity of PS2 in platelet-derived growth factor signaling.

21 January 2018

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Does the risk of developing dementia increase with the number of episodes in patients with depressive disorder and in patients with bipolar disorder?

21 January 2018

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Antidepressants and dementia

21 January 2018

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Amyloid pathology is associated with progressive monoaminergic neurodegeneration in a transgenic mouse model of Alzheimer's disease

21 January 2018

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Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

21 January 2018

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Loss of nerve cells from locus coeruleus in Alzheimer's disease is topographically arranged

21 January 2018

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Elevated monoamine oxidase a levels in the brain: an explanation for the monoamine imbalance of major depression

21 January 2018

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Monoamine oxidase a polymorphism in Brazilian patients: risk factor for late-onset Alzheimer's disease?

21 January 2018

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The selective vulnerability of brainstem nuclei to Alzheimer's disease.

21 January 2018

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Non-cognitive behaviours in an APP/PS1 transgenic model of Alzheimer's disease

21 January 2018

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Female preclinical presenilin-1 mutation carriers unaware of their genetic status have higher levels of depression than their non-mutation carrying kin

21 January 2018

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Amyloid beta-protein assembly and Alzheimer disease

21 January 2018

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The evolution of Alzheimer's disease-related cytoskeletal pathology in the human raphe nuclei

21 January 2018

1 reference

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Presenilin-dependent gamma-secretase processing of beta-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0616-7

Increased monoamine oxidase B activity in plaque-associated astrocytes of Alzheimer brains revealed by quantitative enzyme radioautography

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0616-7

Mutant presenilins disturb neuronal calcium homeostasis in the brain of transgenic mice, decreasing the threshold for excitotoxicity and facilitating long-term potentiation

21 January 2018

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Risk factors for Alzheimer's disease: a case-control study.

21 January 2018

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The presenilin hypothesis of Alzheimer's disease: evidence for a loss-of-function pathogenic mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0616-7

Brain gamma-aminobutyrate aminotransferase (GABA-T) and monoamine oxidase (MAO) in patients with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0616-7

Ca(2+) stores and capacitative Ca(2+) entry in human neuroblastoma (SH-SY5Y) cells expressing a familial Alzheimer's disease presenilin-1 mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0616-7

Late onset loss of hippocampal 5-HT and NE is accompanied by increases in BDNF protein expression in mice co-expressing mutant APP and PS1.

21 January 2018

1 reference

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Association of monoamine oxidase A gene polymorphism with Alzheimer's disease and Lewy body variant.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00702-011-0616-7

Presenilins and Alzheimer disease: the calcium conspiracy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0616-7

Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0616-7

Evidence that levels of presenilins (PS1 and PS2) are coordinately regulated by competition for limiting cellular factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0616-7

Depressive syndromes in dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0616-7

Haloperidol disrupts Akt signalling to reveal a phosphorylation-dependent regulation of pro-apoptotic Bcl-XS function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0616-7

A promoter polymorphism in the monoamine oxidase A gene is associated with the pineal MAOA activity in Alzheimer's disease patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0616-7

The putative neurodegenerative links between depression and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0616-7

Amyloid beta-protein toxicity and the pathogenesis of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0616-7

The neuropathology of aminergic nuclei in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0616-7

Nongenetic factors as modifiers of the age of onset of familial Alzheimer's disease

21 January 2018

2 references

https://api.crossref.org/works/10.1007%2FS00702-011-0616-7

21 January 2018

12 December 2020

C-terminal Fragment of Presenilin Is the Molecular Target of a Dipeptidic γ-Secretase-specific Inhibitor DAPT (N-[N-(3,5-Difluorophenacetyl)-L-alanyl]-S-phenylglycinet-Butyl Ester)

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0616-7

21 January 2018

Connecting Organelles

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0616-7

Protein topology of presenilin 1

21 January 2018

1 reference

12 December 2020

Calcium and ammonia stimulate monoamine oxidase A activity in brain mitochondria

1 reference

12 December 2020

Oligomerization of human presenilin-1 fragments

1 reference

12 December 2020

Alzheimer's APP mangles mitochondria

1 reference

12 December 2020

Nucleus raphe dorsalis in dementia of the Alzheimer type: neurofibrillary changes and neuronal packing density.

1 reference

12 December 2020

Amyloid-beta and mitochondria in aging and Alzheimer's disease: implications for synaptic damage and cognitive decline

1 reference

12 December 2020

Early and persistent alterations in prefrontal cortex MAO A and B in Alzheimer's disease

1 reference

12 December 2020

Calbindin D-28k and monoamine oxidase A immunoreactive neurons in the nucleus basalis of Meynert in senile dementia of the Alzheimer type and Parkinson's disease.

1 reference

12 December 2020

10.1007/S00702-011-0616-7

Identifiers

DOI

1 reference

13 September 2017

1 reference