(Q39586645)

13 September 2017

1 reference

title

The selectivity of austocystin D arises from cell-line-specific drug activation by cytochrome P450 enzymes (English)

1 reference

13 September 2017

1 reference

ChEBI release 2020-05-28

Kevin M Marks

1

1 reference

13 September 2017

Eun Sun Park

2

1 reference

13 September 2017

Alexander Arefolov

3

1 reference

13 September 2017

Katie Russo

4

1 reference

13 September 2017

Keiko Ishihara

5

1 reference

13 September 2017

Jennifer E Ring

6

1 reference

13 September 2017

Jon Clardy

7

1 reference

13 September 2017

Astrid S Clarke

8

1 reference

13 September 2017

Henry E Pelish

9

1 reference

13 September 2017

24 February 2011

1 reference

Journal of Natural Products

13 September 2017

1 reference

13 September 2017

74

1 reference

13 September 2017

4

1 reference

13 September 2017

567-573

1 reference

Cytochrome P450-activated prodrugs: targeted drug delivery.

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081663

Design of new oxazaphosphorine anticancer drugs

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081663

Selective toxicity of NSC73306 in MDR1-positive cells as a new strategy to circumvent multidrug resistance in cancer.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081663

Targeting multidrug resistance in cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081663

Structure of multidrug-resistance proteins of the ATP-binding cassette (ABC) superfamily

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081663

Histone H2AX in DNA damage and repair.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081663

The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081663

The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081663

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081663

Cellular interactions and metabolism of aflatoxin: an update

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081663

Expression of the human multidrug resistance cDNA in insect cells generates a high activity drug-stimulated membrane ATPase

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081663

Mutagenicity of aflatoxins related to their metabolism and carcinogenic potential

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081663

Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081663

Nuclear receptor mediated induction of cytochrome P450 3A4 by anticancer drugs: a key role for the pregnane X receptor

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081663

Expanding the roles for pregnane X receptor in cancer: proliferation and drug resistance in ovarian cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081663

Inhibition of the MDR1 transporter by new phenothiazine derivatives

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081663

Metabolism and toxicity of aflatoxins M1 and B1 in human-derived in vitro systems

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081663

Interaction of bioactive hydrophobic peptides with the human multidrug transporter

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081663

Functional detection of MDR1/P170 and MRP/P190-mediated multidrug resistance in tumour cells by flow cytometry

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081663

The pregnane X receptor regulates gene expression in a ligand- and promoter-selective fashion

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081663

Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081663

Assessment of specificity of eight chemical inhibitors using cDNA-expressed cytochromes P450.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081663

Austocystins. Six novel dihydrofuro (3',2':4,5)furo(3,2-b)xanthenones from Aspergillus ustus

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21348461

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mutagenic activity of austocystins--secondary metabolites of Aspergillus ustus

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21348461

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

DNA strand scission and apurinic sites induced by photoactivated aflatoxins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21348461

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/NP100429S

1 reference

13 September 2017

1 reference

13 September 2017

PubMed publication ID

21348461

1 reference