(Q39601921)

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Interaction between 24-hydroxycholesterol, oxidative stress, and amyloid-β in amplifying neuronal damage in Alzheimer's disease: three partners in crime.

scientific article published on 5 April 2011

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scholarly article

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21 January 2020

Interaction between 24-hydroxycholesterol, oxidative stress, and amyloid-β in amplifying neuronal damage in Alzheimer's disease: three partners in crime (English)

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21 January 2020

Alzheimer's disease

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21 January 2020

Gabriella Leonarduzzi

2

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21 January 2020

Gabriella Testa

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21 January 2020

Alessandro Mauro

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21 January 2020

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21 January 2020

author name string

Elena Tamagno

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21 January 2020

Michela Guglielmotto

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21 January 2020

Barbara Sottero

6

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21 January 2020

Simona Gargiulo

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21 January 2020

Fiorella Biasi

8

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21 January 2020

Giuseppe Poli

11

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21 January 2020

publication date

5 April 2011

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21 January 2020

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21 January 2020

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21 January 2020

3

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21 January 2020

403-417

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21 January 2020

A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00681.X

21 January 2018

Crossing the barrier: oxysterols as cholesterol transporters and metabolic modulators in the brain.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00681.X

21 January 2018

Brain cholesterol: long secret life behind a barrier.

1 reference

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21 January 2018

On the turnover of brain cholesterol in patients with Alzheimer's disease. Abnormal induction of the cholesterol-catabolic enzyme CYP46 in glial cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00681.X

21 January 2018

Oxidative stress in Alzheimer disease: a possibility for prevention

1 reference

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21 January 2018

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

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21 January 2018

Differential expression of cholesterol hydroxylases in Alzheimer's disease

1 reference

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21 January 2018

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

1 reference

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21 January 2018

Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease

1 reference

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21 January 2018

Cholesterol and APOE genotype interact to influence Alzheimer disease progression

1 reference

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21 January 2018

Cholesterol potentiates beta-amyloid-induced toxicity in human neuroblastoma cells: involvement of oxidative stress

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00681.X

21 January 2018

Role of Protein Aggregation in Mitochondrial Dysfunction and Neurodegeneration in Alzheimer's and Parkinson's Diseases

1 reference

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21 January 2018

Crossing the barrier: net flux of 27-hydroxycholesterol into the human brain.

1 reference

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21 January 2018

Substrate deprivation therapy: a new hope for patients suffering from neuronopathic forms of inherited lysosomal storage diseases

1 reference

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21 January 2018

A kinetic model for beta-amyloid adsorption at the air/solution interface and its implication to the beta-amyloid aggregation process

1 reference

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21 January 2018

Statins and the risk of dementia

1 reference

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21 January 2018

The neurotoxic effect of 24-hydroxycholesterol on SH-SY5Y human neuroblastoma cells.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00681.X

21 January 2018

Neurotoxicity of 24-hydroxycholesterol, an important cholesterol elimination product of the brain, may be prevented by vitamin E and estradiol-17beta

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00681.X

21 January 2018

Oxidized products of cholesterol: dietary and metabolic origin, and proatherosclerotic effects (review).

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00681.X

21 January 2018

Oxidation as a crucial reaction for cholesterol to induce tissue degeneration: CD36 overexpression in human promonocytic cells treated with a biologically relevant oxysterol mixture.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00681.X

21 January 2018

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

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21 January 2018

Reduction of plasma 24S-hydroxycholesterol (cerebrosterol) levels using high-dosage simvastatin in patients with hypercholesterolemia: evidence that simvastatin affects cholesterol metabolism in the human brain

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00681.X

21 January 2018

Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00681.X

21 January 2018

Oxidation of cholesterol by amyloid precursor protein and beta-amyloid peptide.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00681.X

21 January 2018

Oxidative damage is the earliest event in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00681.X

21 January 2018

Early glycoxidation damage in brains from Down's syndrome.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00681.X

21 January 2018

Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2).

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00681.X

21 January 2018

Docosahexaenoic acid and synaptic protection in Alzheimer's disease mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00681.X

21 January 2018

A COLORIMETRIC MICRO-METHOD FOR THE DETERMINATION OF GLUTATHIONE

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00681.X

21 January 2018

Total cholesterol levels and the risk of mild cognitive impairment and Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00681.X

21 January 2018

Cholesterol oxidation products in the vascular remodeling due to atherosclerosis.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00681.X

21 January 2018

Alzheimer's disease: the cholesterol connection

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00681.X

21 January 2018

Alzheimer's Disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00681.X

21 January 2018

Adverse stress, hippocampal networks, and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00681.X

21 January 2018

Amyloid oligomers: formation and toxicity of Abeta oligomers

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00681.X

21 January 2018

Mannosylated liposomal flavonoid in combating age-related ischemia-reperfusion induced oxidative damage in rat brain

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00681.X

21 January 2018

Cerebrospinal fluid 24S-hydroxycholesterol is increased in patients with Alzheimer's disease compared to healthy controls

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00681.X

21 January 2018

Normal and abnormal biology of the beta-amyloid precursor protein

1 reference

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21 January 2018

Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment

1 reference

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21 January 2018

Cholesterol oxidation products and disease: an emerging topic of interest in medicinal chemistry.

1 reference

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21 January 2018

Trace amounts of copper in water induce beta-amyloid plaques and learning deficits in a rabbit model of Alzheimer's disease

1 reference

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21 January 2018

NT2 neurons, a classical model for Alzheimer's disease, are highly susceptible to oxidative stress.

1 reference

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21 January 2018

Reduction in levels of 24S-hydroxycholesterol by statin treatment in patients with Alzheimer disease

1 reference

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21 January 2018

Cytotoxic effects of oxysterols associated with human diseases: Induction of cell death (apoptosis and/or oncosis), oxidative and inflammatory activities, and phospholipidosis.

1 reference

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21 January 2018

Amyloid beta-peptide interactions with neuronal and glial cell plasma membrane: binding sites and implications for Alzheimer's disease

1 reference

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21 January 2018

Causes of oxidative stress in Alzheimer disease.

1 reference

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21 January 2018

Alzheimer disease, the two-hit hypothesis: an update

1 reference

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21 January 2018

Identification of an NADH plus iron dependent, Ca2+ activated hydrogen peroxide production in synaptosomes

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21 January 2018

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