(Q39608957)

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Citrus flavonoid 5-demethylnobiletin suppresses scavenger receptor expression in THP-1 cells and alters lipid homeostasis in HepG2 liver cells.

scientific article published on 10 January 2011

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scholarly article

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19 January 2020

Citrus flavonoid 5-demethylnobiletin suppresses scavenger receptor expression in THP-1 cells and alters lipid homeostasis in HepG2 liver cells (English)

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19 January 2020

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19 January 2020

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19 January 2020

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Chi-Tang Ho

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19 January 2020

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Jui-Hung Yen

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19 January 2020

Ching-Yi Weng

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19 January 2020

Shiming Li

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19 January 2020

Ya-Hsuan Lo

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19 January 2020

Shih-Hang Fu

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19 January 2020

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10 January 2011

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19 January 2020

Molecular Nutrition and Food Research

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19 January 2020

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19 January 2020

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19 January 2020

733-748

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19 January 2020

Inflammation in atherosclerosis

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Antihypercholesterolemic property of naringin alters plasma and tissue lipids, cholesterol-regulating enzymes, fecal sterol and tissue morphology in rabbits

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Naringin time-dependently lowers hepatic cholesterol biosynthesis and plasma cholesterol in rats fed high-fat and high-cholesterol diet.

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Hypolipidemic effects and absorption of citrus polymethoxylated flavones in hamsters with diet-induced hypercholesterolemia

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Naringin supplementation lowers plasma lipids and enhances erythrocyte antioxidant enzyme activities in hypercholesterolemic subjects

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Anti-atherogenic effect of citrus flavonoids, naringin and naringenin, associated with hepatic ACAT and aortic VCAM-1 and MCP-1 in high cholesterol-fed rabbits

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21 January 2018

Nobiletin, a citrus flavonoid isolated from tangerines, selectively inhibits class A scavenger receptor-mediated metabolism of acetylated LDL by mouse macrophages

1 reference

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21 January 2018

Nobiletin, a citrus flavonoid, suppresses phorbol ester-induced expression of multiple scavenger receptor genes in THP-1 human monocytic cells.

1 reference

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21 January 2018

Suppressive effects of demethylated metabolites of nobiletin on phorbol ester-induced expression of scavenger receptor genes in THP-1 human monocytic cells

1 reference

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21 January 2018

Nobiletin metabolite, 3',4'-dihydroxy-5,6,7,8-tetramethoxyflavone, inhibits LDL oxidation and down-regulates scavenger receptor expression and activity in THP-1 cells

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21 January 2018

Isolation and syntheses of polymethoxyflavones and hydroxylated polymethoxyflavones as inhibitors of HL-60 cell lines.

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21 January 2018

Monodemethylated polymethoxyflavones from sweet orange (Citrus sinensis) peel inhibit growth of human lung cancer cells by apoptosis

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21 January 2018

Inhibitory effects of 5-hydroxy polymethoxyflavones on colon cancer cells

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21 January 2018

Anti-inflammatory property of the urinary metabolites of nobiletin in mouse

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21 January 2018

Introduction to the plasma lipoproteins

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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21 January 2018

Determination of LDL- and scavenger-receptor activity in adherent and non-adherent cultured cells with a new single-step fluorometric assay

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21 January 2018

Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts

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21 January 2018

A PCR primer bank for quantitative gene expression analysis

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21 January 2018

The absence of activator protein 1-dependent gene expression in THP-1 macrophages stimulated with phorbol esters is due to lack of p38 mitogen-activated protein kinase activation

1 reference

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21 January 2018

Genomic organization and regulation of expression of the lectin-like oxidized low-density lipoprotein receptor (LOX-1) gene

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Nuclear expression of the 50- and 65-kD Rel-related subunits of nuclear factor-kappa B is differentially regulated in human monocytic cells

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21 January 2018

Regulation of Nrf2, NF-kappaB, and AP-1 signaling pathways by chemopreventive agents

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Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members

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Phosphorylation of NF-kappaB and IkappaB proteins: implications in cancer and inflammation

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Peroxisome-proliferator-activated-receptor gamma (PPARgamma) independent induction of CD36 in THP-1 monocytes by retinoic acid

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21 January 2018

Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages

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Synergically increased expression of CD36, CLA-1 and CD68, but not of SR-A and LOX-1, with the progression to foam cells from macrophages

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The NF-kappa B-binding site mediates phorbol ester-inducible transcription in nonlymphoid cells

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c-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases

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Identifiers

10.1002/MNFR.201000226

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21225617%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21225617%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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