(Q39609507)

13 September 2017

title

Rad is a p53 direct transcriptional target that inhibits cell migration and is frequently silenced in lung carcinoma cells (English)

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13 September 2017

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Bo-Yuan Hsiao

1

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13 September 2017

Chun-Chin Chen

2

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13 September 2017

Pei-Chen Hsieh

3

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13 September 2017

Tsun-Kai Chang

4

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13 September 2017

Yi-Chen Yeh

5

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13 September 2017

Yu-Chung Wu

6

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13 September 2017

Han-Shui Hsu

7

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13 September 2017

Fung-Fang Wang

8

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13 September 2017

Teh-Ying Chou

9

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13 September 2017

language of work or name

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11 January 2011

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Journal of Molecular Medicine

13 September 2017

number of pages

12

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based on heuristic

inferred from page(s)

published in

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13 September 2017

volume

89

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13 September 2017

issue

5

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13 September 2017

page(s)

481-492

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https://scigraph.springernature.com/pub.10.1007/s00109-010-0717-z

13 September 2017

exact match

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Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis

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Changes in p53 expression in mouse fibroblasts can modify motility and extracellular matrix organization.

21 January 2018

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Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matrices

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p53 suppresses Src-induced podosome and rosette formation and cellular invasiveness through the upregulation of caldesmon

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Transcriptional repression of epithelial cell adhesion molecule contributes to p53 control of breast cancer invasion

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p53 Attenuates cancer cell migration and invasion through repression of SDF-1/CXCL12 expression in stromal fibroblasts

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Rad: a member of the Ras family overexpressed in muscle of type II diabetic humans

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The GTP binding proteins Gem and Rad are negative regulators of the Rho-Rho kinase pathway

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Direct activation of HSP90A transcription by c-Myc contributes to c-Myc-induced transformation

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A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis

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Interplay between components of a novel LIM kinase-slingshot phosphatase complex regulates cofilin

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Rho family GTPases cooperate with p53 deletion to promote primary mouse embryonic fibroblast cell invasion

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Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinases

21 January 2018

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Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database

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21 January 2018

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based on heuristic

Regulation of growth and tumorigenicity of breast cancer cells by the low molecular weight GTPase Rad and nm23.

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PubMed

https://pubmed.ncbi.nlm.nih.gov/21221513

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00109-010-0717-Z

1 reference

13 September 2017

1 reference