(Q39616144)

English

An unusual syncytia-inducing human immunodeficiency virus type 1 primary isolate from the central nervous system that is restricted to CXCR4, replicates efficiently in macrophages, and induces neuronal apoptosis

scientific article published on August 2003

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scholarly article

1 reference

Europe PubMed Central

13 September 2017

An unusual syncytia-inducing human immunodeficiency virus type 1 primary isolate from the central nervous system that is restricted to CXCR4, replicates efficiently in macrophages, and induces neuronal apoptosis (English)

1 reference

Europe PubMed Central

13 September 2017

Dennis L Kolson

8

object named as

Dennis L Kolson

1 reference

Europe PubMed Central

13 September 2017

author name string

Yanjie Yi

1

1 reference

Europe PubMed Central

13 September 2017

Wei Chen

2

1 reference

Europe PubMed Central

13 September 2017

Ian Frank

3

1 reference

Europe PubMed Central

13 September 2017

Joann Cutilli

4

1 reference

Europe PubMed Central

13 September 2017

Anjali Singh

5

1 reference

Europe PubMed Central

13 September 2017

Linda Starr-Spires

6

1 reference

Europe PubMed Central

13 September 2017

Jerrold Sulcove

7

1 reference

Europe PubMed Central

13 September 2017

Ronald G Collman

9

1 reference

Europe PubMed Central

13 September 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 August 2003

1 reference

Europe PubMed Central

13 September 2017

Journal of NeuroVirology

1 reference

Europe PubMed Central

13 September 2017

9

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Europe PubMed Central

13 September 2017

4

1 reference

Europe PubMed Central

13 September 2017

432-441

1 reference

Europe PubMed Central

13 September 2017

https://scigraph.springernature.com/pub.10.1080/13550280390218706

0 references

The relationship between AIDS dementia complex and the presence of macrophage tropic and non-syncytium inducing isolates of human immunodeficiency virus type 1 in the cerebrospinal fluid.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acetylcholinesterase expression in NTera 2 human neuronal cells: a model for developmental expression in the nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Virus isolation from and identification of HTLV-III/LAV-producing cells in brain tissue from a patient with AIDS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secretion of neurotoxins by mononuclear phagocytes infected with HIV-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of CCR5 in infection of primary macrophages and lymphocytes by macrophage-tropic strains of human immunodeficiency virus: resistance to patient-derived and prototype isolates resulting from the delta ccr5 mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis induced by infection of primary brain cultures with diverse human immunodeficiency virus type 1 isolates: evidence for a role of the envelope.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglia express CCR5, CXCR4, and CCR3, but of these, CCR5 is the principal coreceptor for human immunodeficiency virus type 1 dementia isolates.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebrospinal fluid HIV RNA originates from both local CNS and systemic sources

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional expression of the seven-transmembrane HIV-1 co-receptor APJ in neural cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathways to neuronal injury and apoptosis in HIV-associated dementia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 env sequence variation in brain tissue of patients with AIDS-related neurologic disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CXCR4 as a functional coreceptor for human immunodeficiency virus type 1 infection of primary macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CXCR4 is a functional coreceptor for infection of human macrophages by CXCR4-dependent primary HIV-1 isolates.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patterns of chemokine receptor fusion cofactor utilization by human immunodeficiency virus type 1 variants from the lungs and blood.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophage tropism of human immunodeficiency virus type 1 isolates from brain and lymphoid tissues predicts neurotropism independent of coreceptor specificity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble HIV-1 infected macrophage secretory products mediate blockade of long-term potentiation: a mechanism for cognitive dysfunction in HIV-1-associated dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Infection of monocyte-derived macrophages with human immunodeficiency virus type 1 (HIV-1). Monocyte-tropic and lymphocyte-tropic strains of HIV-1 show distinctive patterns of replication in a panel of cell types

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temporal relationship between V1V2 variation, macrophage replication, and coreceptor adaptation during HIV-1 disease progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence of a source of HIV type 1 within the central nervous system by ultraintensive sampling of cerebrospinal fluid and plasma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemokine receptor expression on resident and inflammatory cells in the brain of macaques with simian immunodeficiency virus encephalitis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of HIV-1 co-receptors CCR5 and CXCR4 in the brain of children with AIDS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular CXCR4 signaling, neuronal apoptosis and neuropathogenic mechanisms of HIV-1-associated dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pure, postmitotic, polarized human neurons derived from NTera 2 cells provide a system for expressing exogenous proteins in terminally differentiated neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Change in coreceptor use correlates with disease progression in HIV-1--infected individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphotropic virions affect chemokine receptor-mediated neural signaling and apoptosis: implications for human immunodeficiency virus type 1-associated dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CXCR4-activated astrocyte glutamate release via TNFalpha: amplification by microglia triggers neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal apoptosis induced by HIV-1 gp120 and the chemokine SDF-1 alpha is mediated by the chemokine receptor CXCR4.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CXCR-4 (Fusin), a co-receptor for the type 1 human immunodeficiency virus (HIV-1), is expressed in the human brain in a variety of cell types, including microglia and neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biological and molecular characterization of human immunodeficiency virus (HIV-1BR) from the brain of a patient with progressive dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of CXCR4 in cell-cell fusion and infection of monocyte-derived macrophages by primary human immunodeficiency virus type 1 (HIV-1) strains: two distinct mechanisms of HIV-1 dual tropism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inducible expression of neuronal glutamate receptor channels in the NT2 human cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CXCR-4 is expressed by primary macrophages and supports CCR5-independent infection by dual-tropic but not T-tropic isolates of human immunodeficiency virus type 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

gp120 induces cell death in human neuroblastoma cells through the CXCR4 and CCR5 chemokine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemokines regulate hippocampal neuronal signaling and gp120 neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolates of human immunodeficiency virus type 1 from the brain may constitute a special group of the AIDS virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An orphan seven-transmembrane domain receptor expressed widely in the brain functions as a coreceptor for human immunodeficiency virus type 1 and simian immunodeficiency virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relation of phenotype evolution of HIV-1 to envelope V2 configuration

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of a human neuronal cell model for human immunodeficiency virus (HIV)-infected macrophage-induced neurotoxicity: apoptosis induced by HIV type 1 primary isolates and evidence for involvement of the Bcl-2/Bcl-xL-sensitive intrinsic apopto

1 reference

https://pubmed.ncbi.nlm.nih.gov/12907388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1080/13550280390218706

1 reference

Europe PubMed Central

13 September 2017

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0 references

1 reference

Europe PubMed Central

13 September 2017

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