(Q39617678)

English

Frequent epigenetic inactivation of KIBRA, an upstream member of the Salvador/Warts/Hippo (SWH) tumor suppressor network, is associated with specific genetic event in B-cell acute lymphocytic leukemia.

scientific article published on March 2011

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21173572%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Frequent epigenetic inactivation of KIBRA, an upstream member of the Salvador/Warts/Hippo (SWH) tumor suppressor network, is associated with specific genetic event in B-cell acute lymphocytic leukemia (English)

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21173572%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

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Thomas L Dunwell

2

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18 January 2020

5

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18 January 2020

Charles Craddock

7

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18 January 2020

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Eamonn R Maher

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18 January 2020

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Victoria K Hill

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18 January 2020

Daniel Catchpoole

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18 January 2020

Dietmar Krex

4

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18 January 2020

Mike Griffiths

6

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18 January 2020

Farida Latif

9

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18 January 2020

publication date

1 March 2011

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18 January 2020

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18 January 2020

6

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18 January 2020

3

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18 January 2020

326-332

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18 January 2020

N-terminal RASSF family: RASSF7-RASSF10.

1 reference

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Pathway discovery in mantle cell lymphoma by integrated analysis of high-resolution gene expression and copy number profiling

1 reference

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14 September 2017

The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis.

1 reference

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14 September 2017

A genome-wide screen identifies frequently methylated genes in haematological and epithelial cancers

1 reference

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14 September 2017

The WW domain protein Kibra acts upstream of Hippo in Drosophila.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092681

14 September 2017

Kibra is a regulator of the Salvador/Warts/Hippo signaling network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092681

14 September 2017

Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092681

14 September 2017

Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092681

14 September 2017

Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression

1 reference

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14 September 2017

An aPKC-exocyst complex controls paxillin phosphorylation and migration through localised JNK1 activation

1 reference

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14 September 2017

A comprehensive microarray-based DNA methylation study of 367 hematological neoplasms

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14 September 2017

The RASSF proteins in cancer; from epigenetic silencing to functional characterization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092681

14 September 2017

Rassf family of tumor suppressor polypeptides.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092681

14 September 2017

Epigenetics in cancer

1 reference

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14 September 2017

The emerging role of the hippo pathway in cell contact inhibition, organ size control, and cancer development in mammals

1 reference

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14 September 2017

RASSF7 is a member of a new family of RAS association domain-containing proteins and is required for completing mitosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092681

14 September 2017

RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092681

14 September 2017

Frequent hypermethylation of MST1 and MST2 in soft tissue sarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092681

14 September 2017

The Salvador-Warts-Hippo pathway - an emerging tumour-suppressor network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092681

14 September 2017

Promoter hypermethylation-mediated down-regulation of LATS1 and LATS2 in human astrocytoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092681

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Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092681

14 September 2017

The fundamental role of epigenetics in hematopoietic malignancies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092681

14 September 2017

Treatment of acute lymphoblastic leukemia

1 reference

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14 September 2017

Down-regulation of LATS1 and LATS2 mRNA expression by promoter hypermethylation and its association with biologically aggressive phenotype in human breast cancers

1 reference

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14 September 2017

KIBRA is a novel substrate for protein kinase Czeta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092681

14 September 2017

Characterization of KIBRA, a novel WW domain-containing protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092681

14 September 2017

Frequent promoter hypermethylation of tumor-related genes in head and neck squamous cell carcinoma

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14 September 2017

The novel RASSF6 and RASSF10 candidate tumour suppressor genes are frequently epigenetically inactivated in childhood leukaemias

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NDR kinase is activated by RASSF1A/MST1 in response to Fas receptor stimulation and promotes apoptosis

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Genome-wide identification of aberrantly methylated promoter associated CpG islands in acute lymphocytic leukemia.

1 reference

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14 September 2017

Frequent epigenetic inactivation of RASSF1A and BLU genes located within the critical 3p21.3 region in gliomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092681

14 September 2017

Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene

1 reference

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15 June 2018

When RASSF1A RAN into tumor suppression: Ran GTPase is a RASSF1A effector involved in controlling microtubule organization.

1 reference

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21 August 2018

RAN GTPase is a RASSF1A effector involved in controlling microtubule organization.

1 reference

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21 August 2018

RASSF1A is part of a complex similar to the Drosophila Hippo/Salvador/Lats tumor-suppressor network.

1 reference

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1 reference

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1 reference

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based on heuristic

inferred from PubMed ID database lookup

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10.4161/EPI.6.3.14404

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Europe PubMed Central

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18 January 2020

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Europe PubMed Central

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18 January 2020

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Europe PubMed Central

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18 January 2020

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