(Q39618849)

English

HA1077, a Rho kinase inhibitor, suppresses glioma-induced angiogenesis by targeting the Rho-ROCK and the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase (MEK/ERK) signal pathways

scientific article published on 19 December 2010

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scholarly article

1 reference

Europe PubMed Central

13 September 2017

HA1077, a Rho kinase inhibitor, suppresses glioma-induced angiogenesis by targeting the Rho-ROCK and the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase (MEK/ERK) signal pathways (English)

1 reference

Europe PubMed Central

13 September 2017

author name string

Hiromichi Nakabayashi

1

1 reference

Europe PubMed Central

13 September 2017

Keiji Shimizu

2

1 reference

Europe PubMed Central

13 September 2017

language of work or name

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publication date

19 December 2010

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Europe PubMed Central

13 September 2017

1 reference

Europe PubMed Central

13 September 2017

102

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Europe PubMed Central

13 September 2017

2

1 reference

Europe PubMed Central

13 September 2017

393-399

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Europe PubMed Central

13 September 2017

Rho GTPases and the actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2010.01794.X

21 January 2018

Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2010.01794.X

21 January 2018

Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2010.01794.X

21 January 2018

Activation of G12/G13 results in shape change and Rho/Rho-kinase-mediated myosin light chain phosphorylation in mouse platelets

1 reference

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21 January 2018

The Rho family guanine nucleotide exchange factor Vav-2 regulates the development of cell-mediated cytotoxicity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2010.01794.X

21 January 2018

Hydroxyfasudil, an active metabolite of fasudil hydrochloride, relaxes the rabbit basilar artery by disinhibition of myosin light chain phosphatase

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2010.01794.X

21 January 2018

Inhibition of rho-kinase-induced myristoylated alanine-rich C kinase substrate (MARCKS) phosphorylation in human neuronal cells by H-1152, a novel and specific Rho-kinase inhibitor.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2010.01794.X

21 January 2018

An essential part for Rho-associated kinase in the transcellular invasion of tumor cells.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2010.01794.X

21 January 2018

Inhibition of intrahepatic metastasis of human hepatocellular carcinoma by Rho-associated protein kinase inhibitor Y-27632.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2010.01794.X

21 January 2018

ROCK and nuclear factor-kappaB-dependent activation of cyclooxygenase-2 by Rho GTPases: effects on tumor growth and therapeutic consequences

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2010.01794.X

21 January 2018

Rho kinase and matrix metalloproteinase inhibitors cooperate to inhibit angiogenesis and growth of human prostate cancer xenotransplants

1 reference

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21 January 2018

Wf-536 prevents tumor metastasis by inhibiting both tumor motility and angiogenic actions

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2010.01794.X

21 January 2018

The Rho kinase inhibitor fasudil inhibits tumor progression in human and rat tumor models

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2010.01794.X

21 January 2018

The Rho kinase inhibitor fasudil inhibits the migratory behaviour of 95-D lung carcinoma cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2010.01794.X

21 January 2018

Rho-kinase inhibitor, fasudil, suppresses glioblastoma cell line progression in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2010.01794.X

21 January 2018

Genetic and hypoxic regulation of angiogenesis in gliomas

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2010.01794.X

21 January 2018

In vivo glioma growth requires host-derived matrix metalloproteinase 2 for maintenance of angioarchitecture.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2010.01794.X

21 January 2018

Proteases and glioma angiogenesis.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2010.01794.X

21 January 2018

Acidic extracellular pH induces vascular endothelial growth factor (VEGF) in human glioblastoma cells via ERK1/2 MAPK signaling pathway: mechanism of low pH-induced VEGF.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2010.01794.X

21 January 2018

Implication of the ERK pathway on the post-transcriptional regulation of VEGF mRNA stability

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2010.01794.X

21 January 2018

Anti-invasive and antiangiogenic effects of MMI-166 on malignant glioma cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2010.01794.X

21 January 2018

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2010.01794.X

21 January 2018

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2010.01794.X

21 January 2018

Transplanted glioma cells migrate and proliferate on host brain vasculature: a dynamic analysis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2010.01794.X

21 January 2018

Multiple Ras functions can contribute to mammalian cell transformation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2010.01794.X

21 January 2018

Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2010.01794.X

21 January 2018

Fasudil hydrochloride hydrate, a Rho-kinase (ROCK) inhibitor, suppresses collagen production and enhances collagenase activity in hepatic stellate cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2010.01794.X

21 January 2018

Specificity and mechanism of action of some commonly used protein kinase inhibitors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2010.01794.X

21 January 2018

PD 098059, an inhibitor of ERK1 activation, attenuates the in vivo invasiveness of head and neck squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2010.01794.X

21 January 2018

Multiple signaling pathways involved in activation of matrix metalloproteinase-9 (MMP-9) by heregulin-beta1 in human breast cancer cells

1 reference

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21 January 2018

Identifiers

10.1111/J.1349-7006.2010.01794.X

1 reference

Europe PubMed Central

13 September 2017

1 reference

Europe PubMed Central

13 September 2017

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