(Q28587227)

Guanine nucleotide binding protein, alpha 12

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

S. Offermanns

5

0 references

author name string

B. Klages

1

1 reference

31 January 2017

U. Brandt

2

1 reference

31 January 2017

M. I. Simon

3

1 reference

31 January 2017

G. Schultz

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

4

1 reference

31 January 2017

language of work or name

English

0 references

publication date

22 February 1999

1 reference

31 January 2017

Journal of Cell Biology

1 reference

31 January 2017

144

1 reference

31 January 2017

745–754

1 reference

31 January 2017

4

1 reference

31 January 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13

17 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

17 March 2017

https://api.crossref.org/works/10.1083%2FJCB.144.4.745

Regulation of myosin phosphatase through phosphorylation of the myosin-binding subunit in platelet activation

28 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Focal adhesions, contractility, and signaling

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Signaling by the G12 class of G proteins

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Specificity of G alpha q and G alpha 11 gene expression in platelets and erythrocytes. Expressions of cellular differentiation and species differences

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

The G protein coupled to the thromboxane A2 receptor in human platelets is a member of the novel Gq family

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Diversity of G proteins in signal transduction

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

cAMP-induced morphological changes are counteracted by the activated RhoA small GTPase and the Rho kinase ROKalpha

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

The Rho GTPase and a putative RhoGEF mediate a signaling pathway for the cell shape changes in Drosophila gastrulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Cytoskeletal rearrangements and transcriptional activation of c-fos serum response element by Rho-kinase.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

The small GTP-binding protein Rho links G protein-coupled receptors and Galpha12 to the serum response element and to cellular transformation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Myosin light chain kinase: an actin-binding protein that regulates an ATP-dependent interaction with myosin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

G alpha 13 stimulates Na+-H+ exchange through distinct Cdc42-dependent and RhoA-dependent pathways

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Tyrosine kinases in platelet signalling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Signal transduction and regulation in smooth muscle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Redistribution of activated pp60c-src to integrin-dependent cytoskeletal complexes in thrombin-stimulated platelets

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Evidence for a role of myosin phosphorylation in the initiation of the platelet shape change response

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Molecular mechanisms of platelet activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Thrombin treatment induces rapid changes in tyrosine phosphorylation in platelets

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Platelet tyrosine-specific protein phosphorylation is regulated by thrombin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Formation and contraction of a microfilamentous shell in saponin-permeabilized platelets

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Purification and characterization of platelet myosin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Molecular dissection of the Rho-associated protein kinase (p160ROCK)-regulated neurite remodeling in neuroblastoma N1E-115 cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Myosin II activation promotes neurite retraction during the action of Rho and Rho-kinase.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Integrin-dependent translocation of p160ROCK to cytoskeletal complex in thrombin-stimulated human platelets

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Rho effectors and reorganization of actin cytoskeleton

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Thromboxane A2-mediated shape change: independent of Gq-phospholipase C--Ca2+ pathway in rabbit platelets

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Protein-tyrosine kinase p72syk is activated by thrombin and is negatively regulated through Ca2+ mobilization in platelets

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Protein-tyrosine kinase p72syk is activated by thromboxane A2 mimetic U44069 in platelets

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Distribution and relative levels of expression of the phosphoinositidase-C-linked G-proteins Gq alpha and G11 alpha: absence of G11 alpha in human platelets and haemopoietically derived cell lines

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Functional reconstitution of platelet thromboxane A2 receptors with Gq and Gi2 in phospholipid vesicles

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Platelet shape change induced by thrombin receptor activation. Rapid stimulation of tyrosine phosphorylation of novel protein substrates through an integrin- and Ca(2+)-independent mechanism

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

G alpha 12 and G alpha 13 stimulate Rho-dependent stress fiber formation and focal adhesion assembly

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Low concentrations of the stable prostaglandin endoperoxide U44069 stimulate shape change in quin2-loaded platelets without a measurable increase in [Ca2+]i

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Platelet activating factor and U44069 stimulate a GTPase activity in human platelets which is distinct from the guanine nucleotide regulatory proteins, Ns and Ni.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

25 Identification of receptor-activated G proteins with photoreactive GTP analog, α-32PGTP azidoanilide

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

The cloned platelet thrombin receptor couples to at least two distinct effectors to stimulate phosphoinositide hydrolysis and inhibit adenylyl cyclase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Platelet activation leads to increased c-src kinase activity and association of c-src with an 85-kDa tyrosine phosphoprotein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132941

Thrombin inactivates myosin light chain phosphatase via Rho and its target Rho kinase in human endothelial cells.

3 June 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.144.4.745

The G-protein G13 but not G12 mediates signaling from lysophosphatidic acid receptor via epidermal growth factor receptor to Rho.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.144.4.745

Identification of receptor-activated G proteins: selective immunoprecipitation of photolabeled G-protein alpha subunits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.144.4.745

Requirement for Rho-mediated myosin light chain phosphorylation in thrombin-stimulated cell rounding and its dissociation from mitogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.144.4.745

Defective platelet activation in G alpha(q)-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.144.4.745

The alpha-subunit of the heterotrimeric G protein G13 activates a phospholipase D isozyme by a pathway requiring Rho family GTPases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.144.4.745

Cytoplasmic free Ca2+ in human platelets: Ca2+ thresholds and Ca-independent activation for shape-change and secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.144.4.745

Involvement of Protein-Tyrosine Kinase p72syk in Collagen-Induced Signal Transduction in Platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.144.4.745

Reversible association of myosin with the platelet cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.144.4.745

A rho gene product in human blood platelets. II. Effects of the ADP-ribosylation by botulinum C3 ADP-ribosyltransferase on platelet aggregation

21 January 2018

1 reference

12 December 2020

Influence of the cGMP analog 8-PCPT-cGMP on agonist-induced increases in cytosolic ionized Ca2+ and on aggregation of human platelets

1 reference

12 December 2020

The platelet cytoskeleton

1 reference

12 December 2020

Regulation of the protein tyrosine kinase pp72syk by platelet agonists and the integrin alpha IIb beta 3

1 reference

12 December 2020

Clustering of the platelet Fc gamma receptor induces noncovalent association with the tyrosine kinase p72syk

1 reference

12 December 2020

Regulation of protein tyrosine kinases in platelets

1 reference

12 December 2020

Thrombin receptor ligation and activated Rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets

1 reference

12 December 2020

Dissociation of the alphaIIbbeta3-integrin by EGTA stimulates the tyrosine kinase pp72(syk) without inducing platelet activation

1 reference

12 December 2020

Non-receptor protein tyrosine kinases and phosphatases in human platelets

1 reference

12 December 2020

Signaling through G proteins in platelets: to the integrins and beyond

1 reference

12 December 2020

RhoA and the function of platelet integrin alphaIIbbeta3

1 reference

12 December 2020

Assay of cyclic nucleotides by receptor protein binding displacement

1 reference

12 December 2020

Role of phosphorylation in mediating the association of myosin with the cytoskeletal structures of human platelets

1 reference

12 December 2020

Ni-mediated inhibition of human platelet adenylate cyclase by thrombin

1 reference

12 December 2020

Interactions in platelets between G proteins and the agonists that stimulate phospholipase C and inhibit adenylyl cyclase

1 reference

12 December 2020

Thrombin and collagen induce rapid phosphorylation of a common set of cellular proteins on tyrosine in human platelets

1 reference

12 December 2020

Possible involvement of protein-tyrosine kinases such as p72syk in the disc-sphere change response of porcine platelets

1 reference

12 December 2020