(Q39630283)

13 September 2017

Inhibition of HIV-1 fusion with small interfering RNAs targeting the chemokine coreceptor CXCR4. (English)

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13 September 2017

Zhou N

1

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13 September 2017

Fang J

2

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13 September 2017

Mukhtar M

3

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13 September 2017

Acheampong E

4

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13 September 2017

Pomerantz RJ

5

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13 September 2017

1 December 2004

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13 September 2017

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13 September 2017

11

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13 September 2017

23

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13 September 2017

1703-1712

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https://scigraph.springernature.com/pub.10.1038/sj.gt.3302339

13 September 2017

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

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RNA interference is mediated by 21- and 22-nucleotide RNAs

21 January 2018

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Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

21 January 2018

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Specific interference with gene function by double-stranded RNA in early mouse development

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21 January 2018

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RNA-dependent RNA polymerases, viruses, and RNA silencing

21 January 2018

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RNA interference--a new weapon against HIV and beyond

21 January 2018

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Virus-encoded suppressor of posttranscriptional gene silencing targets a maintenance step in the silencing pathway

21 January 2018

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Effective expression of small interfering RNA in human cells

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21 January 2018

RNA interference--2001.

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Gene silencing as an adaptive defence against viruses

21 January 2018

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RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells

21 January 2018

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RNAi as random degradative PCR: siRNA primers convert mRNA into dsRNAs that are degraded to generate new siRNAs.

21 January 2018

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On the role of RNA amplification in dsRNA-triggered gene silencing

21 January 2018

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Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways.

21 January 2018

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U6 promoter-driven siRNAs with four uridine 3' overhangs efficiently suppress targeted gene expression in mammalian cells.

21 January 2018

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Induction and suppression of RNA silencing by an animal virus

21 January 2018

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The molecular biology of leukocyte chemoattractant receptors

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors

21 January 2018

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HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

21 January 2018

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The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1

21 January 2018

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Structural and functional characterization of human CXCR4 as a chemokine receptor and HIV-1 co-receptor by mutagenesis and molecular modeling studies

21 January 2018

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Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice

21 January 2018

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Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

21 January 2018

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Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

In vivo evolution of HIV-1 co-receptor usage and sensitivity to chemokine-mediated suppression.

21 January 2018

1 reference

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CXCR4 utilization is sufficient to trigger CD4+ T cell depletion in HIV-1-infected human lymphoid tissue

21 January 2018

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Viral entry through CXCR4 is a pathogenic factor and therapeutic target in human immunodeficiency virus type 1 disease

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

Binding of ALX40-4C to APJ, a CNS-based receptor, inhibits its utilization as a co-receptor by HIV-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

Inhibition of HIV-1 infection by down-regulation of the CXCR4 co-receptor using an intracellular single chain variable fragment against CXCR4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

Inactivation of HIV-1 chemokine co-receptor CXCR-4 by a novel intrakine strategy

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

Safe use of the CXCR4 inhibitor ALX40-4C in humans

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

Short interfering RNA confers intracellular antiviral immunity in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

Small Interfering RNA-Mediated Inhibition of Hepatitis C Virus Replication in the Human Hepatoma Cell Line Huh-7

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

Inhibition of HIV-1 infection by small interfering RNA-mediated RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

Modulation of HIV-1 replication by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

Cloned zebrafish by nuclear transfer from long-term-cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

RNA interference directed against viral and cellular targets inhibits human immunodeficiency Virus Type 1 replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

A small-molecule inhibitor directed against the chemokine receptor CXCR4 prevents its use as an HIV-1 coreceptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

Antisense oligodeoxynucleotide complementary to CXCR4 mRNA block replication of HIV-1 in COS cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

Inhibition of T-tropic HIV strains by selective antagonization of the chemokine receptor CXCR4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

Development of specific CXCR4 inhibitors possessing high selectivity indexes as well as complete stability in serum based on an anti-HIV peptide T140.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

Molecular and functional characteristics of APJ. Tissue distribution of mRNA and interaction with the endogenous ligand apelin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

Apelin, the natural ligand of the orphan seven-transmembrane receptor APJ, inhibits human immunodeficiency virus type 1 entry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

Cell-cell fusion and internalization of the CNS-based, HIV-1 co-receptor, APJ

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

Chemokine receptors in HIV-1 infection of the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

Primary isolated human brain microvascular endothelial cells express diverse HIV/SIV-associated chemokine coreceptors and DC-SIGN and L-SIGN.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

CD4-independent association between HIV-1 gp120 and CXCR4: functional chemokine receptors are expressed in human neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

RNAi functions in cultured mammalian neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

RNA interference meets HIV-1: will silence be golden?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

7 January 2021

RNA interference targeting Fas protects mice from fulminant hepatitis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

7 January 2021

A viral movement protein prevents spread of the gene silencing signal in Nicotiana benthamiana

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

7 January 2021

Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

7 January 2021

siRNA-directed inhibition of HIV-1 infection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

7 January 2021

An orphan seven-transmembrane domain receptor expressed widely in the brain functions as a coreceptor for human immunodeficiency virus type 1 and simian immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

7 January 2021

Suppression of chemokine receptor expression by RNA interference allows for inhibition of HIV-1 replication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

7 January 2021

Fusogenic mechanisms of enveloped-virus glycoproteins analyzed by a novel recombinant vaccinia virus-based assay quantitating cell fusion-dependent reporter gene activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302339

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3302339

1 reference

13 September 2017

1 reference