(Q39635714)

13 September 2017

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title

PAF antagonists. Their potential therapeutic role in asthma (English)

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13 September 2017

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K F Chung

1

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PubMed ID

3281823

13 September 2017

P J Barnes

series ordinal

2

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13 September 2017

1 February 1988

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13 September 2017

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13 September 2017

35

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13 September 2017

2

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13 September 2017

93-103

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https://scigraph.springernature.com/pub.10.2165/00003495-198835020-00001

13 September 2017

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cites work

Reduction of bronchial hyperreactivity during prolonged allergen avoidance

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12 December 2020

trans-2,5-Bis-(3,4,5-trimethoxyphenyl)tetrahydrofuran. An orally active specific and competitive receptor antagonist of platelet activating factor.

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12 December 2020

The changing face of asthma

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12 December 2020

Platelet-activating factor as a mediator of allergic disease

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12 December 2020

Recurrent nocturnal asthma after exposure to grain dust

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12 December 2020

Asthma as an axon reflex

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12 December 2020

Increased biosynthesis of platelet-activating factor in activated human eosinophils

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12 December 2020

Role of platelet-activating factor-acether in mediating guinea pig anaphylaxis

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12 December 2020

Platelet activating factor (PAF) involvement in endotoxin-induced hypotension in rats. Studies with PAF-receptor antagonist kadsurenone.

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12 December 2020

AGEPC (platelet activating factor) induced stimulation of rabbit platelets: effects on phosphatidylinositol, di- and triphosphoinositides and phosphatidic acid metabolism

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12 December 2020

Allergen-induced increase in non-allergic bronchial reactivity

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12 December 2020

Effects of leukotriene D on the airways in asthma

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12 December 2020

Effects of a thromboxane synthetase inhibitor (OKY-046) and a lipoxygenase inhibitor (AA-861) on bronchial responsiveness to acetylcholine in asthmatic subjects

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12 December 2020

Studies of platelet activating factor (PAF) antagonists from microbial products. II. Pharmacological studies of FR-49175 in animal models.

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12 December 2020

Damage of the airway epithelium and bronchial reactivity in patients with asthma

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12 December 2020

The late reaction following bronchial provocation with house dust mite allergen. Dependence on arachidonic acid metabolism

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12 December 2020

Simple method for quantitation of enhanced vascular permeability.

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12 December 2020

Effect of platelet-activating factor on airway vascular permeability: possible mechanisms.

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12 December 2020

Effects of ketotifen upon responses to platelet activating factor: a basis for asthma prophylaxis

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12 December 2020

Platelet-activating factor. A potent chemotactic and chemokinetic factor for human eosinophils.

1 reference

12 December 2020

Metabolism of platelet-activating factor in isolated perfused rat lung

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12 December 2020

Imaging in rheumatoid arthritis using liposomes labelled with technetium

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12 December 2020

Histamine modulation of eosinophil migration

1 reference

12 December 2020

A clinical and pathological study of fatal cases of status asthmaticus

1 reference

12 December 2020

Pharmacokinetic study of 3H-labelled PAF-acether II. Comparison with 3H-labelled lyso-PAF-acether after intravenous administration in the rabbit and protein binding

1 reference

12 December 2020

Non-steroidal anti-inflammatory drugs if combined with anti-histamine and anti-serotonin agents interfere with the bronchial and platelet effects of "platelet-activating factor" (PAF-acether).

1 reference

12 December 2020

The bronchoconstrictor effect of inhaled prostaglandin D2 in normal and asthmatic men.

1 reference

12 December 2020

Accumulation of eosinophils in response to intracutaneous PAF-acether and allergens in man

1 reference

12 December 2020

Asthma and increases in nonallergic bronchial responsiveness from seasonal pollen exposure

1 reference

12 December 2020

L-652,469--a dual receptor antagonist of platelet activating factor and dihydropyridines from Tussilago farfara L

1 reference

12 December 2020

Chemical and biochemical aspects of platelet activating factor: a novel class of acetylated ether-linked choline-phospholipids

1 reference

12 December 2020

Slow-reacting substances, leukotrienes C4 and D4, increase the release of mucus from human airways in vitro

1 reference

12 December 2020

Structure elucidation of platelet activating factor derived from human neutrophils

1 reference

12 December 2020

Comparative effects of inhaled leukotriene C4, leukotriene D4, and histamine in normal human subjects

1 reference

12 December 2020

Platelet activating factor: a biologically active phosphoglyceride

1 reference

12 December 2020

CV-3988 - a specific antagonist of platelet activating factor (PAF)

1 reference

12 December 2020

Platelet-activating factor induces a platelet-dependent bronchoconstriction unrelated to the formation of prostaglandin derivatives

1 reference

12 December 2020

Effects of inhaled platelet activating factor on pulmonary function and bronchial responsiveness in man

1 reference

12 December 2020

Antigenic release of paf-acether and beta-glucuronidase from alveolar macrophages of asthmatics

1 reference

12 December 2020

Triazolodiazepines: dissociation of their Paf (platelet activating factor) antagonistic and CNS activity

1 reference

12 December 2020

The release of platelet-activating factor from human endothelial cells in culture

1 reference

12 December 2020

Bronchoalveolar eosinophilia during allergen-induced late asthmatic reactions

1 reference

12 December 2020

Bronchoconstrictor effects of leukotriene E4 in normal and asthmatic subjects

1 reference

12 December 2020

Specific binding by human polymorphonuclear leucocytes of the immunological mediator 1-O-hexadecyl/octadecyl-2-acetyl-sn-glycero-3-phosphorylcholine

1 reference

12 December 2020

The eosinophil and the pathophysiology of asthma

1 reference

12 December 2020

Characterization of a platelet-activating factor receptor antagonist isolated from haifenteng (Piper futokadsura): specific inhibition of in vitro and in vivo platelet-activating factor-induced effects

1 reference

12 December 2020

Effects of Inhaled Prostaglandins E1, E2 and F2α on the Airway Resistance of Healthy and Asthmatic Man

1 reference

12 December 2020

Role of inflammation in the hyperreactivity of the airways in asthma

1 reference

12 December 2020

The intracellular retention of newly synthesized platelet-activating factor

1 reference

12 December 2020

Purification and synthesis of eosinophilotactic tetrapeptides of human lung tissue: identification as eosinophil chemotactic factor of anaphylaxis

1 reference

12 December 2020

Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: in vivo effects with relevance to the acute inflammatory response

1 reference

12 December 2020

Bronchoalveolar mast cells in extrinsic asthma: a mechanism for the initiation of antigen specific bronchoconstriction.

1 reference

12 December 2020

Airway responsiveness to histamine and methacholine: relationship to minimum treatment to control symptoms of asthma

1 reference

12 December 2020

Local effects of synthetic leukotrienes (LTC4, LTD4, LTE4, and LTB4) in human skin

1 reference

12 December 2020

Acute effects of intratracheal administration of platelet-activating factor in baboons.

1 reference

12 December 2020

The role of histamine and its receptors in the pathogenesis of asthma

1 reference

12 December 2020

Characterization of inflammatory mediator release from purified human lung mast cells

1 reference

12 December 2020

Platelet-activating factor (PAF-acether) secretion from platelets: effect of aggregating agents

1 reference

12 December 2020

Are asthma mortality rates changing?

1 reference

12 December 2020

The pathology of asthma, with special reference to changes in the bronchial mucosa

1 reference

12 December 2020

Effect of an inhaled antihistamine (clemastine) as a bronchodilator and as a maintenance treatment in asthma

1 reference

12 December 2020

The anaphylactic release of platelet-activating factor from perfused guinea-pig lungs

1 reference

12 December 2020

Protective effect of WEB 2086, a novel antagonist of platelet activating factor, in endotoxin shock

1 reference

12 December 2020

Characteristics of the binding of platelet-activating factor to platelets of different animal species.

1 reference

12 December 2020

Platelet-Activating Factor-Induced Aggregation of Human Platelets Specifically Inhibited by Triazolobenzodiazepines

1 reference

12 December 2020

Inhibition of PAF-acether induced weal and flare reaction in man by a specific PAF antagonist

1 reference

12 December 2020

Inhibition of antigen-induced lung anaphylaxis in the guinea-pig by BN 52021 a new specific paf-acether receptor antagonist isolated from Ginkgo biloba

1 reference

12 December 2020

Cromoglycate (DSCG) inhibits responses to platelet-activating factor (PAF-acether) in man: an alternative mode of action for DSCG in asthma?

1 reference

12 December 2020

Mechanics of airway narrowing

1 reference

12 December 2020

Prevalence of asthma and hay fever in England and Wales

1 reference

12 December 2020

Inflammatory leakage of macromolecules from the vascular compartment into the tracheal lumen.

1 reference

12 December 2020

Bronchial biopsy in chronic bronchitis and asthma

1 reference

12 December 2020

Airway hyperresponsiveness induced by platelet-activating factor: role of thromboxane generation.

1 reference

12 December 2020

Functional assessment of alveolar macrophages: comparison of cells from asthmatics and normal subjects

1 reference

12 December 2020

Cultured endothelial cells synthesize both platelet-activating factor and prostacyclin in response to histamine, bradykinin, and adenosine triphosphate

1 reference

12 December 2020

The effect of an oral leukotriene D4 antagonist L-649,923 on the response to inhaled antigen in asthma.

1 reference

12 December 2020

Participation of platelets in the physiologic alterations of the AGEPC response and of IgE anaphylaxis in the rabbit. Effects of PGI2 inhibition of platelet function

1 reference

12 December 2020

Asthma mortality in England and Wales: evidence for a further increase, 1974-84

1 reference

12 December 2020

Specific binding sites for platelet activating factor in human lung tissues

1 reference

12 December 2020

Bronchial hyperreactivity

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12 December 2020

Increases in deaths from asthma

1 reference

12 December 2020

Respiratory and circulatory alterations induced by acetyl glyceryl ether phosphorylcholine, a mediator of IgE anaphylaxis in the rabbit

1 reference

12 December 2020

Effect of a ginkgolide mixture (BN 52063) in antagonising skin and platelet responses to platelet activating factor in man

1 reference

12 December 2020

Prostaglandin D2 potentiates airway responsiveness to histamine and methacholine

1 reference

12 December 2020

Specific binding of phospholipid platelet-activating factor by human platelets

1 reference

12 December 2020

Indomethacin inhibits the airway hyperresponsiveness but not the neutrophil influx induced by ozone in dogs

1 reference

12 December 2020

Effect of a PAF antagonist, BN52063, on antigen-induced, acute, and late-onset cutaneous responses in atopic subjects

1 reference

12 December 2020

The effect of airway epithelium on smooth muscle contractility in bovine trachea

1 reference

12 December 2020

Nonspecific bronchial reactivity in occupational asthma

1 reference

12 December 2020

Binding and metabolism of platelet-activating factor by human neutrophils

1 reference

12 December 2020

Leukocyte-dependent histamine release from rabbit platelets. The role of IgE, basophils, and a platelet-activating factor

1 reference

12 December 2020

Interference of the PAF-acether antagonist BN 52021 with passive anaphylaxis in the guinea-pig

1 reference

12 December 2020

Respiratory epithelium inhibits bronchial smooth muscle tone

1 reference

12 December 2020

Human endothelial cells in culture produce platelet-activating factor (1-alkyl-2-acetyl-sn-glycero-3-phosphocholine) when stimulated with thrombin

1 reference

12 December 2020

Induction of bronchial hypersensitivity: evidence for a role for prostaglandins

1 reference

12 December 2020

Biology and biochemistry of platelet-activating factor

1 reference

12 December 2020

Airways hyperreactivity and inflammation produced by aerosolization of human C5A des arg.

1 reference

12 December 2020

10.2165/00003495-198835020-00001

Identifiers

DOI

1 reference

PubMed ID

3281823

Dimensions Publication ID

13 September 2017

0 references

1 reference

PubMed ID

3281823