(Q39637745)

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Editor's Highlight: Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS): A Web-Based Tool for Addressing the Challenges of Cross-Species Extrapolation of Chemical Toxicity.

scientific article published on 30 June 2016

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27370413%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Editor's Highlight: Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS): A Web-Based Tool for Addressing the Challenges of Cross-Species Extrapolation of Chemical Toxicity (English)

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17 March 2020

sequence alignment

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based on heuristic

inferred from title

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17 March 2020

Gerald T Ankley

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Gerald T Ankley

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17 March 2020

Daniel L Villeneuve

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Daniel L Villeneuve

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17 March 2020

Carlie A LaLone

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Carlie A LaLone

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17 March 2020

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Travis W Saari

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17 March 2020

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Henry W Helgen

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17 March 2020

Serina L Robinson

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Serina L Robinson

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17 March 2020

author name string

Joseph A Swintek

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17 March 2020

publication date

30 June 2016

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17 March 2020

Toxicological Sciences

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17 March 2020

153

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17 March 2020

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17 March 2020

228-245

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17 March 2020

Resolving the ortholog conjecture: orthologs tend to be weakly, but significantly, more similar in function than paralogs

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Basic local alignment search tool

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Selectivity of diacylhydrazine insecticides to the predatory bug Orius laevigatus: in vivo and modelling/docking experiments.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

DynaDock: A new molecular dynamics-based algorithm for protein-peptide docking including receptor flexibility.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Review of strobilurin fungicide chemicals

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

The strobilurin fungicides

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Mutation of a nicotinic acetylcholine receptor β subunit is associated with resistance to neonicotinoid insecticides in the aphid Myzus persicae

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

The Protein Data Bank

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Structural adaptability in the ligand-binding pocket of the ecdysone hormone receptor

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Rapid divergence of the ecdysone receptor in Diptera and Lepidoptera suggests coevolution between ECR and USP-RXR.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

The chemical and biological properties of methoxyfenozide, a new insecticidal ecdysteroid agonist

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Protein flexibility is an important component of structure-based drug discovery.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

The X-ray structure of a hemipteran ecdysone receptor ligand-binding domain: comparison with a lepidopteran ecdysone receptor ligand-binding domain and implications for insecticide design

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Cytochrome b phylogeny and the taxonomy of great apes and mammals

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Structure-activity relationships of acetylcholine derivatives with Lucilia cuprina nicotinic acetylcholine receptor α1 and α2 subunits in chicken β2 subunit hybrid receptors in comparison with chicken nicotinic acetylcholine receptor α4/β2.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

The effect of strobilurins on leaf gas exchange, water use efficiency and ABA content in grapevine under field conditions.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Applied aspects of neonicotinoid uses in crop protection

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Association of neonicotinoid insensitivity with a conserved residue in the loop d binding region of the tick nicotinic acetylcholine receptor.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Cytochrome b gene structure and consequences for resistance to Qo inhibitor fungicides in plant pathogens.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

A hypothesis to account for the selective and diverse actions of neonicotinoid insecticides at their molecular targets, nicotinic acetylcholine receptors: catch and release in hydrogen bond networks.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Occurrence and molecular characterization of strobilurin resistance in cucumber powdery mildew and downy mildew

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Effect of Seed Quality and Combination Fungicide-Trichoderma spp. Seed Treatments on Pre- and Postemergence Damping-Off in Cotton

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Neonicotinoids-from zero to hero in insecticide chemistry

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

The nicotinic acetylcholine receptor gene family of the honey bee, Apis mellifera.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Update on EPA's ToxCast program: providing high throughput decision support tools for chemical risk management.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Field Resistance to Strobilurin (Q(o)I) Fungicides in Pyricularia grisea Caused by Mutations in the Mitochondrial Cytochrome b Gene

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Molecular target sequence similarity as a basis for species extrapolation to assess the ecological risk of chemicals with known modes of action

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Clustal W and Clustal X version 2.0

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

OrthoMCL: Identification of Ortholog Groups for Eukaryotic Genomes

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

UniProt Knowledgebase: a hub of integrated protein data

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

CDD: a Conserved Domain Database for the functional annotation of proteins

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Role of loop D of the alpha7 nicotinic acetylcholine receptor in its interaction with the insecticide imidacloprid and related neonicotinoids

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

In silico analysis of the conservation of human toxicity and endocrine disruption targets in aquatic species

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

COBALT: constraint-based alignment tool for multiple protein sequences

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Automatic clustering of orthologs and in-paralogs from pairwise species comparisons

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Occurrence, fate and effects of azoxystrobin in aquatic ecosystems: a review.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Development of an adverse outcome pathway for acetylcholinesterase inhibition leading to acute mortality

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Advances in the control of Ctenocephalides felis (cat flea) on cats and dogs

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Insect-vertebrate chimeric nicotinic acetylcholine receptors identify a region, loop B to the N-terminus of the Drosophila Dalpha2 subunit, which contributes to neonicotinoid sensitivity

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Role in the selectivity of neonicotinoids of insect-specific basic residues in loop D of the nicotinic acetylcholine receptor agonist binding site

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Roles of loop C and the loop B-C interval of the nicotinic receptor alpha subunit in its selective interactions with imidacloprid in insects

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Combinatorial mutations in loops D and F strongly influence responses of the alpha7 nicotinic acetylcholine receptor to imidacloprid

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

A genomic perspective on protein families

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Selective toxicity of neonicotinoids attributable to specificity of insect and mammalian nicotinic receptors

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Structure and diversity of insect nicotinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Atypical nicotinic agonist bound conformations conferring subtype selectivity

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW119

21 January 2018

Combined roles of loops C and D in the interactions of a neonicotinoid insecticide imidacloprid with the alpha4beta2 nicotinic acetylcholine receptor

1 reference

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Molecular docking: a potential tool to aid ecotoxicity testing in environmental risk assessment of pharmaceuticals

1 reference

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Clonal variation in physiological responses of Daphnia magna to the strobilurin fungicide azoxystrobin

1 reference

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21 January 2018

Identifiers

10.1093/TOXSCI/KFW119

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27370413%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27370413%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

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