(Q39643077)

13 September 2017

title

Anti-leukemic activity of dasatinib in both p53(wild-type) and p53(mutated) B malignant cells (English)

1 reference

13 September 2017

1 reference

dasatinib monohydrate

1 reference

1 reference

7

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13 September 2017

Silvano Capitani

6

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author name string

Raffaella Bosco

1

1 reference

13 September 2017

Marco Rabusin

2

1 reference

13 September 2017

Rebecca Voltan

3

1 reference

13 September 2017

Claudio Celeghini

4

1 reference

13 September 2017

Federica Corallini

5

1 reference

13 September 2017

publication date

16 October 2010

1 reference

Investigational New Drugs

13 September 2017

published in

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13 September 2017

volume

30

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13 September 2017

issue

1

1 reference

13 September 2017

page(s)

417-422

1 reference

https://scigraph.springernature.com/pub.10.1007/s10637-010-9564-6

13 September 2017

exact match

0 references

cites work

Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9564-6

The kinase inhibitor dasatinib induces apoptosis in chronic lymphocytic leukemia cells in vitro with preference for a subgroup of patients with unmutated IgVH genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9564-6

Synergistic cytotoxic activity of recombinant TRAIL plus the non-genotoxic activator of the p53 pathway nutlin-3 in acute myeloid leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9564-6

The MDM-2 antagonist nutlin-3 promotes the maturation of acute myeloid leukemic blasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9564-6

Gene expression profile of protein kinases reveals a distinctive signature in chronic lymphocytic leukemia and in vitro experiments support a role of second generation protein kinase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9564-6

Monoallelic TP53 inactivation is associated with poor prognosis in chronic lymphocytic leukemia: results from a detailed genetic characterization with long-term follow-up

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9564-6

Human immunodeficiency virus type 1 envelope glycoprotein gp120-mediated killing of human haematopoietic progenitors (CD34+ cells).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9564-6

Extracellular human immunodeficiency virus type-1 Tat protein activates phosphatidylinositol 3-kinase in PC12 neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9564-6

Phase I dose-escalation and pharmacokinetic study of dasatinib in patients with advanced solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9564-6

IL-24 induces apoptosis of chronic lymphocytic leukemia B cells engaged into the cell cycle through dephosphorylation of STAT3 and stabilization of p53 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9564-6

Curcumin inhibits prosurvival pathways in chronic lymphocytic leukemia B cells and may overcome their stromal protection in combination with EGCG.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9564-6

Activated human NK and CD8+ T cells express both TNF-related apoptosis-inducing ligand (TRAIL) and TRAIL receptors but are resistant to TRAIL-mediated cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9564-6

CREB is a critical regulator of normal hematopoiesis and leukemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9564-6

Dasatinib sensitizes primary chronic lymphocytic leukaemia lymphocytes to chlorambucil and fludarabinein vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9564-6

TRAIL promotes the survival, migration and proliferation of vascular smooth muscle cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20953816

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Tumour necrosis factor-related apoptosis-inducing ligand sequentially activates pro-survival and pro-apoptotic pathways in SK-N-MC neuronal cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20953816

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S10637-010-9564-6

1 reference

13 September 2017

1 reference