(Q39643658)

13 September 2017

title

Nicotine and cotinine increases the brain penetration of saquinavir in rat (English)

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

3 August 2024

1 reference

5

Paul R. Lockman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20950334

3 August 2024

author name string

Vamshi K. Manda

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20950334

3 August 2024

Rajendar K. Mittapalli

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20950334

3 August 2024

Kaci A. Bohn

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20950334

3 August 2024

Chris E. Adkins

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20950334

3 August 2024

language of work or name

English

0 references

publication date

11 November 2010

1 reference

full work available at URL

13 September 2017

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1471-4159.2010.07054.x

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1471-4159.2010.07054.x

3 August 2024

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Journal of Neurochemistry

3 August 2024

published in

1 reference

13 September 2017

volume

115

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13 September 2017

issue

6

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13 September 2017

page(s)

1495-1507

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Effect of smoking on the clinical progression of HIV-1 infection

13 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2010.07054.X

Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2010.07054.X

Nicotine and cotinine modulate cerebral microvascular permeability and protein expression of ZO-1 through nicotinic acetylcholine receptors expressed on brain endothelial cells

21 January 2018

1

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Distribution of gefitinib to the brain is limited by P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2)-mediated active efflux

3 August 2024

2

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Characterization of the blood-brain barrier choline transporter using the in situ rat brain perfusion technique

3 August 2024

3

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Active transport of high-affinity choline and nicotine analogs into the central nervous system by the blood-brain barrier choline transporter

3 August 2024

4

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Quantitative assessment of HIV-1 protease inhibitor interactions with drug efflux transporters in the blood-brain barrier.

3 August 2024

5

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

ABC transporters and the blood-brain barrier

3 August 2024

6

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Tobacco addiction and HIV infection: toward the implementation of cessation programs. ANRS CO3 Aquitaine Cohort

3 August 2024

7

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Sources of variability in nicotine and cotinine levels with use of nicotine nasal spray, transdermal nicotine, and cigarette smoking

3 August 2024

8

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Transport of alpha-aminoisobutyric acid across brain capillary and cellular membranes

3 August 2024

9

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Cigarette smoking, bacterial pneumonia, and other clinical outcomes in HIV-1 infection. Terry Beirn Community Programs for Clinical Research on AIDS

3 August 2024

10

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Nicotine raises the influx of permeable solutes across the rat blood-brain barrier with little or no capillary recruitment

3 August 2024

11

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

P-glycoprotein and breast cancer resistance protein influence brain distribution of dasatinib

3 August 2024

12

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Expression, up-regulation, and transport activity of the multidrug-resistance protein Abcg2 at the mouse blood-brain barrier.

3 August 2024

13

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Randomized study of dual versus single ritonavir-enhanced protease inhibitors for protease inhibitor-experienced patients with HIV.

3 August 2024

14

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

In vivo characterization of a novel inhibitor of CNS nicotinic receptors

3 August 2024

16

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Use of osmotic minipumps for sustained drug delivery in rat pups: effects on physical and neurobehavioural development.

3 August 2024

17

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

HIV protease inhibitors are inhibitors but not substrates of the human breast cancer resistance protein (BCRP/ABCG2).

3 August 2024

22

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Xenobiotic transporters of the human organic anion transporting polypeptides (OATP) family

3 August 2024

23

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

17-β-Estradiol: a powerful modulator of blood-brain barrier BCRP activity

3 August 2024

24

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Nicotine dependence and HIV risk behaviors among illicit drug users

3 August 2024

25

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Factors associated with altered pharmacokinetics in substance users and non-substance users receiving lopinavir and atazanavir

3 August 2024

26

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Molecular physiology and pathophysiology of tight junctions in the blood-brain barrier

3 August 2024

27

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

P-glycoprotein limits oral availability, brain, and fetal penetration of saquinavir even with high doses of ritonavir

3 August 2024

28

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Assessing safety and efficacy of directed P-glycoprotein inhibition to improve the pharmacokinetic properties of saquinavir coadministered with ritonavir

3 August 2024

29

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Different pharmacokinetics of nicotine following intravenous administration of nicotine base and nicotine hydrogen tartarate in rats

3 August 2024

30

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Modulation of the intracellular accumulation of saquinavir in peripheral blood mononuclear cells by inhibitors of MRP1, MRP2, P-gp and BCRP.

3 August 2024

31

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Cultured CD4T cells and primary human lymphocytes express hOATPs: intracellular accumulation of saquinavir and lopinavir

3 August 2024

32

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Does highly active antiretroviral therapy improve neurocognitive function? A systematic review

3 August 2024

33

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Quantitative atlas of membrane transporter proteins: development and application of a highly sensitive simultaneous LC/MS/MS method combined with novel in-silico peptide selection criteria

3 August 2024

34

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Kinetic analyses for species differences in P-glycoprotein-mediated drug transport.

3 August 2024

35

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors

3 August 2024

36

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Kinetic analysis of the cooperation of P-glycoprotein (P-gp/Abcb1) and breast cancer resistance protein (Bcrp/Abcg2) in limiting the brain and testis penetration of erlotinib, flavopiridol, and mitoxantrone

3 August 2024

37

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Brain accumulation of dasatinib is restricted by P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) and can be enhanced by elacridar treatment

3 August 2024

38

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Molecular characterization and inhibition of amanitin uptake into human hepatocytes

3 August 2024

39

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

HIV-associated neurocognitive disorder: pathogenesis and therapeutic opportunities

3 August 2024

40

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Interaction between nicotine and MPTP/MPP+ in rat brain endothelial cells

3 August 2024

41

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Inhibition of the rat blood-brain barrier choline transporter by manganese chloride

3 August 2024

42

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Evaluation of blood-brain barrier thiamine efflux using the in situ rat brain perfusion method

3 August 2024

43

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Cation transport specificity at the blood-brain barrier

3 August 2024

44

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Brain uptake kinetics of nicotine and cotinine after chronic nicotine exposure

3 August 2024

45

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Chronic nicotine exposure alters blood-brain barrier permeability and diminishes brain uptake of methyllycaconitine

3 August 2024

46

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Nicotine exposure does not alter plasma to brain choline transfer

3 August 2024

47

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

A fluorescence-based in vitro assay for drug interactions with breast cancer resistance protein (BCRP, ABCG2).

3 August 2024

48

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Chronic exposure to nicotine and saquinavir decreases endothelial Notch‐4 expression and disrupts blood‐brain barrier integrity

3 August 2024

49

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Role of site-specific binding to plasma albumin in drug availability to brain

3 August 2024

50

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Communication between multiple drug binding sites on P-glycoprotein

3 August 2024

51

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Human serum attenuates the activity of protease inhibitors toward wild-type and mutant human immunodeficiency virus

3 August 2024

53

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

HPLC quantification of the HIV-1 protease inhibitor saquinavir in brain and testis of mice

3 August 2024

54

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Characterization of substrates and inhibitors for the in vitro assessment of Bcrp mediated drug-drug interactions

3 August 2024

55

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Influence of highly active antiretroviral therapy on persistence of HIV in the central nervous system

3 August 2024

56

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Human immunodeficiency virus infection, AIDS, and smoking cessation: the time is now.

3 August 2024

57

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Lower limits of cerebrovascular permeability to nonelectrolytes in the conscious rat

3 August 2024

58

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Importance of baseline cotinine plasma values in smoking cessation: results from a double-blind study with nicotine patch

3 August 2024

59

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

P-glycoprotein and mutlidrug resistance-associated proteins limit the brain uptake of saquinavir in mice

3 August 2024

60

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

A functional in vitro model of rat blood-brain barrier for molecular analysis of efflux transporters

3 August 2024

62

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Saquinavir: a review of its use in boosted regimens for treating HIV infection

3 August 2024

63

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Stimulation of P-glycoprotein-mediated drug transport by prazosin and progesterone. Evidence for a third drug-binding site.

3 August 2024

65

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Independent evolution of human immunodeficiency virus (HIV) drug resistance mutations in diverse areas of the brain in HIV-infected patients, with and without dementia, on antiretroviral treatment

3 August 2024

66

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Human organic anion-transporting polypeptide OATP-A (SLC21A3) acts in concert with P-glycoprotein and multidrug resistance protein 2 in the vectorial transport of Saquinavir in Hep G2 cells

3 August 2024

68

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Chronic nicotine treatment enhances focal ischemic brain injury and depletes free pool of brain microvascular tissue plasminogen activator in rats

3 August 2024

70

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

P-glycoprotein does not actively transport nicotine and cotinine

3 August 2024

71

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Modulation of human BCRP (ABCG2) activity by anti-HIV drugs

3 August 2024

72

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

The Safety, Efficacy, and Pharmacokinetic Profile of a Switch in Antiretroviral Therapy to Saquinavir, Ritonavir, and Atazanavir Alone for 48 Weeks and a Switch in the Saquinavir Formulation

3 August 2024

73

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Different effects of three transporting inhibitors, verapamil, cimetidine, and probenecid, on fexofenadine pharmacokinetics

3 August 2024

74

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Cerebrospinal fluid HIV-1 RNA, intrathecal immunoactivation, and drug concentrations after treatment with a combination of saquinavir, nelfinavir, and two nucleoside analogues: the M61022 study

3 August 2024

75

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Blood-brain barrier permeability to leucine-enkephalin, D-alanine2-D-leucine5-enkephalin and their N-terminal amino acid (tyrosine).

3 August 2024

76

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

Transport, uptake, and metabolism of blood-borne vasopressin by the blood-brain barrier

3 August 2024

77

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2010.07054.X

3 August 2024

Identifiers

1 reference

13 September 2017

1 reference