(Q39656026)

English

Inhibition of microsomal prostaglandin E2 synthase-1 as a molecular basis for the anti-inflammatory actions of boswellic acids from frankincense

scientific article published on January 2011

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scholarly article

1 reference

Europe PubMed Central

13 September 2017

Inhibition of microsomal prostaglandin E2 synthase-1 as a molecular basis for the anti-inflammatory actions of boswellic acids from frankincense (English)

1 reference

Europe PubMed Central

13 September 2017

0 references

1 reference

β-boswellic acid

1 reference

(4R,6aR,8aR,12S,12aR,14bR)-3-hydroxy-4,6a,6b,8a,11,12,14b-heptamethyl-2,3,4a,5,6,7,8,9,10,11,12,12a,14,14a-tetradecahydro-1H-picene-4-carboxylic acid

1 reference

prostaglandin E2

1 reference

based on heuristic

inferred from title

object named as

F Bernhard

10

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author name string

U Siemoneit

1

1 reference

Europe PubMed Central

13 September 2017

A Koeberle

2

1 reference

Europe PubMed Central

13 September 2017

A Rossi

3

1 reference

Europe PubMed Central

13 September 2017

F Dehm

4

1 reference

Europe PubMed Central

13 September 2017

M Verhoff

5

1 reference

Europe PubMed Central

13 September 2017

S Reckel

6

1 reference

Europe PubMed Central

13 September 2017

T J Maier

7

1 reference

Europe PubMed Central

13 September 2017

J Jauch

8

1 reference

Europe PubMed Central

13 September 2017

H Northoff

9

1 reference

Europe PubMed Central

13 September 2017

V Doetsch

11

1 reference

Europe PubMed Central

13 September 2017

L Sautebin

12

1 reference

Europe PubMed Central

13 September 2017

O Werz

13

1 reference

Europe PubMed Central

13 September 2017

language of work or name

0 references

publication date

1 January 2011

1 reference

Europe PubMed Central

13 September 2017

full work available at URL

https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1476-5381.2010.01020.x

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1111/j.1476-5381.2010.01020.x?email=unpaywall_01@example.com

British Journal of Pharmacology

1 reference

Europe PubMed Central

13 September 2017

162

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Europe PubMed Central

13 September 2017

1

1 reference

Europe PubMed Central

13 September 2017

147-162

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Europe PubMed Central

13 September 2017

online access status

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1111/j.1476-5381.2010.01020.x?email=unpaywall_01@example.com

access restriction status

1 reference

based on heuristic

inferred from online access status

Inhibitors of the microsomal prostaglandin E(2) synthase-1 as alternative to non steroidal anti-inflammatory drugs (NSAIDs)--a critical review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012413

14 September 2017

Boswellic acid blocks signal transducers and activators of transcription 3 signaling, proliferation, and survival of multiple myeloma via the protein tyrosine phosphatase SHP-1.

1 reference

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A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin for treatment of osteoarthritis of the knee

1 reference

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14 September 2017

MF63 [2-(6-chloro-1H-phenanthro[9,10-d]imidazol-2-yl)-isophthalonitrile], a selective microsomal prostaglandin E synthase-1 inhibitor, relieves pyresis and pain in preclinical models of inflammation

1 reference

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14 September 2017

Membrane prostaglandin E synthase-1: a novel therapeutic target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012413

14 September 2017

Boswellic acids: biological actions and molecular targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012413

14 September 2017

Boswellic acids in chronic inflammatory diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012413

14 September 2017

Deletion of microsomal prostaglandin E synthase-1 augments prostacyclin and retards atherogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012413

14 September 2017

Preparative scale cell-free expression systems: new tools for the large scale preparation of integral membrane proteins for functional and structural studies

1 reference

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14 September 2017

Therapeutic options for 5-lipoxygenase inhibitors

1 reference

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14 September 2017

Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012413

14 September 2017

Carrageenan-induced paw edema in rat elicits a predominant prostaglandin E2 (PGE2) response in the central nervous system associated with the induction of microsomal PGE2 synthase-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012413

14 September 2017

Impaired inflammatory and pain responses in mice lacking an inducible prostaglandin E synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012413

14 September 2017

Microsomal Prostaglandin E Synthase-1 Is a Major Terminal Synthase That Is Selectively Up-Regulated During Cyclooxygenase-2-Dependent Prostaglandin E2 Production in the Rat Adjuvant-Induced Arthritis Model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012413

14 September 2017

Prostaglandin E synthase

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012413

14 September 2017

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01020.X

21 January 2018

Prostaglandins and leukotrienes: advances in eicosanoid biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012413

14 September 2017

Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012413

14 September 2017

The eicosanoids and their biochemical mechanisms of action

1 reference

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14 September 2017

Comparative effects of drugs on four paw oedema models in the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012413

14 September 2017

Myrtucommulone, a natural acylphloroglucinol, inhibits microsomal prostaglandin E(2) synthase-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012413

14 September 2017

Permeation of Boswellia extract in the Caco-2 model and possible interactions of its constituents KBA and AKBA with OATP1B3 and MRP2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012413

14 September 2017

3-O-acetyl-11-keto-boswellic acid decreases basal intracellular Ca2+ levels and inhibits agonist-induced Ca2+ mobilization and mitogen-activated protein kinase activation in human monocytic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012413

14 September 2017

Prostaglandin G/H synthase-2 is the constitutive and dominant isoform in cultured human lung epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012413

25 September 2017

Effect of food intake on the bioavailability of boswellic acids from a herbal preparation in healthy volunteers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012413

15 June 2018

Changes in the levels of prostaglandins and thromboxane and their roles in the accumulation of exudate in rat carrageenin-induced pleurisy--a profile analysis using gas chromatography-mass spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012413

15 June 2018

Identification of human cathepsin G as a functional target of boswellic acids from the anti-inflammatory remedy frankincense

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012413

21 August 2018

On the interference of boswellic acids with 5-lipoxygenase: mechanistic studies in vitro and pharmacological relevance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012413

21 August 2018

Licofelone suppresses prostaglandin E2 formation by interference with the inducible microsomal prostaglandin E2 synthase-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012413

21 August 2018

The gastric ulcer protective effect of boswellic acids, a leukotriene inhibitor from Boswellia serrata, in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012413

21 August 2018

Identification and functional analysis of cyclooxygenase-1 as a molecular target of boswellic acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012413

21 August 2018

Expression and regulation of microsomal prostaglandin E synthase-1 in human osteoarthritic cartilage and chondrocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012413

21 August 2018

Expression of microsomal prostaglandin E synthase 1 in rheumatoid arthritis synovium

1 reference

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21 August 2018

Experimental design for kinetic analysis of protein-protein interactions with surface plasmon resonance biosensors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012413

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Guide to Receptors and Channels (GRAC), 4th Edition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012413

1 October 2018

Metabolism of Boswellic Acids in Vitro and in Vivo

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01020.X

21 January 2018

Boswellic acids and glucosamine show synergistic effect in preclinical anti-inflammatory study in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20840544

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Global analysis of a macromolecular interaction measured on BIAcore

1 reference

https://pubmed.ncbi.nlm.nih.gov/20840544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition by boswellic acids of human leukocyte elastase

1 reference

https://pubmed.ncbi.nlm.nih.gov/20840544

12 December 2020

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inferred from PubMed ID database lookup

Acetyl-boswellic acids inhibit lipopolysaccharide-mediated TNF-alpha induction in monocytes by direct interaction with IkappaB kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/20840544

12 December 2020

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Surface plasmon resonance based assay for the detection and characterization of promiscuous inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20840544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Are the anti-inflammatory effects of dexamethasone responsible for inhibition of the induction of enzymes involved in prostanoid formation in rat carrageenin-induced pleurisy?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20840544

12 December 2020

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inferred from PubMed ID database lookup

Boswellic acids stimulate arachidonic acid release and 12-lipoxygenase activity in human platelets independent of Ca2+ and differentially interact with platelet-type 12-lipoxygenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/20840544

12 December 2020

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inferred from PubMed ID database lookup

Coordinate up- and down-regulation of glutathione-dependent prostaglandin E synthase and cyclooxygenase-2 in A549 cells. Inhibition by NS-398 and leukotriene C4

1 reference

https://pubmed.ncbi.nlm.nih.gov/20840544

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inferred from PubMed ID database lookup

Analysis of 12 different pentacyclic triterpenic acids from frankincense in human plasma by high-performance liquid chromatography and photodiode array detection

1 reference

https://pubmed.ncbi.nlm.nih.gov/20840544

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Boswellic acids: novel, specific, nonredox inhibitors of 5-lipoxygenase

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https://pubmed.ncbi.nlm.nih.gov/20840544

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1476-5381.2010.01020.X

1 reference

Europe PubMed Central

13 September 2017

1 reference

Europe PubMed Central

13 September 2017

1 reference

Europe PubMed Central

13 September 2017

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