(Q39659854)

13 September 2017

title

Functional dissection of the N-terminal degron of human thymidylate synthase (English)

1 reference

13 September 2017

Sandra P Melo

1

1 reference

13 September 2017

Asami Yoshida

series ordinal

2

1 reference

13 September 2017

Franklin G Berger

series ordinal

3

1 reference

13 September 2017

language of work or name

English

0 references

publication date

1 November 2010

1 reference

13 September 2017

1 reference

13 September 2017

volume

432

1 reference

13 September 2017

issue

1

1 reference

13 September 2017

page(s)

217-226

1 reference

The ubiquitin-proteasome pathway: on protein death and cell life

13 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

Mobilizing the proteolytic machine: cell biological roles of proteasome activators and inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

Toward an atomic model of the 26S proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

Recognition and processing of ubiquitin-protein conjugates by the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

Proteasomes and their kin: proteases in the machine age

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

The base of the proteasome regulatory particle exhibits chaperone-like activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

PA200, a nuclear proteasome activator involved in DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

Ubiquitin-independent proteolytic functions of the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

Determinants of proteasome recognition of ornithine decarboxylase, a ubiquitin-independent substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

Proteasome substrate degradation requires association plus extended peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

Structural elements of the ubiquitin-independent proteasome degron of ornithine decarboxylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

c-Fos Proto-Oncoprotein Is Degraded by the Proteasome Independently of Its Own Ubiquitinylation In Vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

Ubiquitin-independent- versus ubiquitin-dependent proteasomal degradation of the c-Fos and Fra-1 transcription factors: is there a unique answer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

Ubiquitin- and ATP-independent proteolytic turnover of p21 by the REGgamma-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

Ubiquitin-independent degradation of cell-cycle inhibitors by the REGgamma proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

Susceptibility of p53 unstructured N terminus to 20 S proteasomal degradation programs the stress response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

MDM2 promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

Ubiquitin-independent degradation of hepatitis C virus F protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

The SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

Proteasomes can degrade a significant proportion of cellular proteins independent of ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

Proteasomes begin ornithine decarboxylase digestion at the C terminus

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

Intrinsic structural disorder of the C-terminal activation domain from the bZIP transcription factor Fos

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

Mammalian Sug1 and c-Fos in the nuclear 26S proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

A degradation signal located in the C-terminus of p21WAF1/CIP1 is a binding site for the C8 alpha-subunit of the 20S proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

An unstructured initiation site is required for efficient proteasome-mediated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

The catalytic mechanism and structure of thymidylate synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

Structural determinants for the intracellular degradation of human thymidylate synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

The intrinsically disordered N-terminal domain of thymidylate synthase targets the enzyme to the ubiquitin-independent proteasomal degradation pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

Role of N-terminal residues in the ubiquitin-independent degradation of human thymidylate synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

Human thymidylate synthase is in the closed conformation when complexed with dUMP and raltitrexed, an antifolate drug

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

Crystal structure of human thymidylate synthase: a structural mechanism for guiding substrates into the active site

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

Degradation of some polyubiquitinated proteins requires an intrinsic proteasomal binding element in the substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

20S proteasome differentially alters translation of different mRNAs via the cleavage of eIF4F and eIF3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

Endoproteolytic activity of the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

The structural determinants responsible for c-Fos protein proteasomal degradation differ according to the conditions of expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

Stable inhibition of human thymidylate synthase expression following retroviral introduction of an siRNA gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

ODN 491, a novel antisense oligodeoxynucleotide that targets thymidylate synthase, exerts cell-specific effects in human tumor cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

Small interfering double-stranded RNAs as therapeutic molecules to restore chemosensitivity to thymidylate synthase inhibitor compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101027

21 January 2018

Identifiers

DOI

10.1042/BJ20101027

1 reference

13 September 2017

1 reference