(Q39663702)

English

Interaction with Vascular Endothelium Enhances Survival in Primary Chronic Lymphocytic Leukemia Cells via NF-κB Activation andDe novoGene Transcription

scientific article published on August 24, 2010

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736369%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Interaction with vascular endothelium enhances survival in primary chronic lymphocytic leukemia cells via NF-kappaB activation and de novo gene transcription (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736369%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Interaction with Vascular Endothelium Enhances Survival in Primary Chronic Lymphocytic Leukemia Cells via NF-κB Activation andDe novoGene Transcription (English)

1 reference

10.1158/0008-5472.CAN-10-1634

https://api.crossref.org/works/10.1158/0008-5472.CAN-10-1634

22 June 2024

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1 reference

based on heuristic

inferred from title

chronic lymphocytic leukemia

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736369%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Stephen Devereux

12

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736369%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

2

object named as

Chris Pepper

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20736369

22 June 2024

author name string

Piers E M Patten

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736369%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Saman Hewamana

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736369%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Jane Moorhead

6

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736369%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Najeem'deen Folarin

7

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736369%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Deborah Yallop

8

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736369%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

N Shaun B Thomas

9

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736369%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Ghulam J Mufti

10

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736369%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Chris Fegan

11

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736369%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Andrea G. S. Buggins

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20736369

22 June 2024

Piers E. M. Patten

4

0000-0003-3320-3034

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20736369

22 June 2024

N. Shaun B. Thomas

10

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20736369

22 June 2024

Ghulam J. Mufti

11

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20736369

22 June 2024

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24 August 2010

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736369%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

full work available at URL

https://aacr.figshare.com/articles/journal_contribution/Supplementary_Figure_1_from_Interaction_with_Vascular_Endothelium_Enhances_Survival_in_Primary_Chronic_Lymphocytic_Leukemia_Cells_via_NF-_B_Activation_and_i_De_novo_i_Gene_Transcription/22384823/1/files/39830252.pdf

Portable Document Format

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20736369

22 June 2024

http://cancerres.aacrjournals.org/cgi/content/abstract/70/19/7523

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20736369

22 June 2024

https://aacrjournals.org/cancerres/article-pdf/70/19/7523/2638590/7523.pdf

Portable Document Format

1 reference

10.1158/0008-5472.CAN-10-1634

https://api.crossref.org/works/10.1158/0008-5472.CAN-10-1634

22 June 2024

Cancer Research

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736369%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

70

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736369%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

19

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736369%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

7523-7533

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736369%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells

1

1 reference

10.1158/0008-5472.CAN-10-1634

https://api.crossref.org/works/10.1158/0008-5472.CAN-10-1634

22 June 2024

BAFF and APRIL support chronic lymphocytic leukemia B-cell survival through activation of the canonical NF-kappaB pathway

2

1 reference

10.1158/0008-5472.CAN-10-1634

https://api.crossref.org/works/10.1158/0008-5472.CAN-10-1634

22 June 2024

Bone marrow fibroblasts induce expression of PI3K/NF-kappaB pathway genes and a pro-angiogenic phenotype in CLL cells

3

1 reference

10.1158/0008-5472.CAN-10-1634

https://api.crossref.org/works/10.1158/0008-5472.CAN-10-1634

22 June 2024

Modulation of NF-kappa B activity and apoptosis in chronic lymphocytic leukemia B cells

4

1 reference

10.1158/0008-5472.CAN-10-1634

https://api.crossref.org/works/10.1158/0008-5472.CAN-10-1634

22 June 2024

CD38 expression in chronic lymphocytic leukemia is regulated by the tumor microenvironment

5

1 reference

10.1158/0008-5472.CAN-10-1634

https://api.crossref.org/works/10.1158/0008-5472.CAN-10-1634

22 June 2024

CD38 and CD100 lead a network of surface receptors relaying positive signals for B-CLL growth and survival

6

1 reference

10.1158/0008-5472.CAN-10-1634

https://api.crossref.org/works/10.1158/0008-5472.CAN-10-1634

22 June 2024

CD38/CD31, the CCL3 and CCL4 chemokines, and CD49d/vascular cell adhesion molecule-1 are interchained by sequential events sustaining chronic lymphocytic leukemia cell survival

7

1 reference

10.1158/0008-5472.CAN-10-1634

https://api.crossref.org/works/10.1158/0008-5472.CAN-10-1634

22 June 2024

CD49d expression is an independent predictor of overall survival in patients with chronic lymphocytic leukaemia: a prognostic parameter with therapeutic potential

9

1 reference

10.1158/0008-5472.CAN-10-1634

https://api.crossref.org/works/10.1158/0008-5472.CAN-10-1634

22 June 2024

CD154 induces a switch in pro-survival Bcl-2 family members in chronic lymphocytic leukaemia.

12

1 reference

10.1158/0008-5472.CAN-10-1634

https://api.crossref.org/works/10.1158/0008-5472.CAN-10-1634

22 June 2024

CD100/Plexin-B1 interactions sustain proliferation and survival of normal and leukemic CD5+ B lymphocytes

13

1 reference

10.1158/0008-5472.CAN-10-1634

https://api.crossref.org/works/10.1158/0008-5472.CAN-10-1634

22 June 2024

The role of Bcl-2 family proteins in chronic lymphocytic leukaemia

14

1 reference

10.1158/0008-5472.CAN-10-1634

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22 June 2024

Bcl-2 expression in chronic lymphocytic leukemia and its correlation with the induction of apoptosis and clinical outcome

16

1 reference

10.1158/0008-5472.CAN-10-1634

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22 June 2024

Expression profile of 11 proteins and their prognostic significance in patients with chronic lymphocytic leukemia (CLL).

17

1 reference

10.1158/0008-5472.CAN-10-1634

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22 June 2024

miR-15 and miR-16 induce apoptosis by targeting BCL2

19

1 reference

10.1158/0008-5472.CAN-10-1634

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22 June 2024

Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers.

20

1 reference

10.1158/0008-5472.CAN-10-1634

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22 June 2024

Apoptotic-regulatory and complement-protecting protein expression in chronic lymphocytic leukemia: relationship to in vivo rituximab resistance

21

1 reference

10.1158/0008-5472.CAN-10-1634

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22 June 2024

Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: development of a reliable and reproducible system to assess stromal cell adhesion-mediated drug resistance

22

1 reference

10.1158/0008-5472.CAN-10-1634

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22 June 2024

The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells

23

1 reference

10.1158/0008-5472.CAN-10-1634

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22 June 2024

Differential Noxa/Mcl-1 balance in peripheral versus lymph node chronic lymphocytic leukemia cells correlates with survival capacity

24

1 reference

10.1158/0008-5472.CAN-10-1634

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22 June 2024

Concurrent up-regulation of BCL-XL and BCL2A1 induces approximately 1000-fold resistance to ABT-737 in chronic lymphocytic leukemia

25

1 reference

10.1158/0008-5472.CAN-10-1634

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22 June 2024

MCL-1, a member of the BLC-2 family, is induced rapidly in response to signals for cell differentiation or death, but not to signals for cell proliferation

26

1 reference

10.1158/0008-5472.CAN-10-1634

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22 June 2024

NF-kappaB in cancer: from innocent bystander to major culprit

27

1 reference

10.1158/0008-5472.CAN-10-1634

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22 June 2024

A sustained activation of PI3K/NF-kappaB pathway is critical for the survival of chronic lymphocytic leukemia B cells.

28

1 reference

10.1158/0008-5472.CAN-10-1634

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22 June 2024

Rel a is an independent biomarker of clinical outcome in chronic lymphocytic leukemia.

29

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22 June 2024

Transcriptional regulation of bcl-2 by nuclear factor kappa B and its significance in prostate cancer

30

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10.1158/0008-5472.CAN-10-1634

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22 June 2024

The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L).

31

1 reference

10.1158/0008-5472.CAN-10-1634

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22 June 2024

The novel nuclear factor-kappaB inhibitor LC-1 is equipotent in poor prognostic subsets of chronic lymphocytic leukemia and shows strong synergy with fludarabine

32

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10.1158/0008-5472.CAN-10-1634

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22 June 2024

The NF-kappaB subunit Rel A is associated with in vitro survival and clinical disease progression in chronic lymphocytic leukemia and represents a promising therapeutic target

33

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10.1158/0008-5472.CAN-10-1634

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22 June 2024

Regulation of the cd38 promoter in human airway smooth muscle cells by TNF-alpha and dexamethasone

34

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10.1158/0008-5472.CAN-10-1634

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The role of tumor necrosis factor alpha in the pathophysiology of human multiple myeloma: therapeutic applications

35

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10.1158/0008-5472.CAN-10-1634

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CLL, but not normal, B cells are dependent on autocrine VEGF and alpha4beta1 integrin for chemokine-induced motility on and through endothelium

36

1 reference

10.1158/0008-5472.CAN-10-1634

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22 June 2024

Highly purified CD38+ and CD38- sub-clones derived from the same chronic lymphocytic leukemia patient have distinct gene expression signatures despite their monoclonal origin.

37

1 reference

10.1158/0008-5472.CAN-10-1634

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22 June 2024

Elevated Bcl-2/Bax are a consistent feature of apoptosis resistance in B-cell chronic lymphocytic leukaemia and are correlated with in vivo chemoresistance.

38

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Mechanisms of Bcl-2 family protein function and dysfunction in health and disease

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10.1158/0008-5472.CAN-10-1634

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22 June 2024

Role of the microenvironment in chronic lymphocytic leukaemia

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10.1158/0008-5472.CAN-10-1634

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Microenvironmental interactions and survival of CLL B-cells

42

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10.1158/0008-5472.CAN-10-1634

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Differential effects on CLL cell survival exerted by different microenvironmental elements

43

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10.1158/0008-5472.CAN-10-1634

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Small peptide inhibitors of the CXCR4 chemokine receptor (CD184) antagonize the activation, migration, and antiapoptotic responses of CXCL12 in chronic lymphocytic leukemia B cells.

44

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10.1158/0008-5472.CAN-10-1634

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The cellular biology of B-cell chronic lymphocytic leukemia

45

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10.1158/0008-5472.CAN-10-1634

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Efficient nucleofection of primary human B cells and B-CLL cells induces apoptosis, which depends on the microenvironment and on the structure of transfected nucleic acids

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VEGF receptor phosphorylation status and apoptosis is modulated by a green tea component, epigallocatechin-3-gallate (EGCG), in B-cell chronic lymphocytic leukemia

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10.1158/0008-5472.CAN-10-1634

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An impaired transendothelial migration potential of chronic lymphocytic leukemia (CLL) cells can be linked to ephrin-A4 expression

48

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10.1158/0008-5472.CAN-10-1634

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Circulating B-cell chronic lymphocytic leukemia cells display impaired migration to lymph nodes and bone marrow.

49

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NF-kappa B modulates sensitivity to apoptosis, proinflammatory and migratory potential in short- versus long-term cultured human gamma delta lymphocytes

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