(Q39672164)

13 September 2017

title

Participation of DNA-PKcs in DSB repair after exposure to high- and low-LET radiation (English)

1 reference

13 September 2017

Participation of DNA-PKcs in DSB Repair after Exposure to High- and Low-LET Radiation (English)

1 reference

15 June 2024

author name string

Peter O'Neill

4

1 reference

13 September 2017

Jennifer A. Anderson

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20681786

15 June 2024

Jane V. Harper

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20681786

15 June 2024

Francis A. Cucinotta

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20681786

15 June 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20681786

15 June 2024

publication date

1 August 2010

1 reference

full work available at URL

13 September 2017

http://www.bioone.org/bioone/?request=get-abstract&issn=0033-7587&volume=174&issue=02&page=0195

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20681786

15 June 2024

1 reference

13 September 2017

volume

174

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13 September 2017

issue

2

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13 September 2017

page(s)

195-205

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Spatial and Temporal Distribution of Energy

13 September 2017

cites work

1

1 reference

Initial events in the cellular effects of ionizing radiations: clustered damage in DNA.

15 June 2024

3

1 reference

Interplay of two major repair pathways in the processing of complex double-strand DNA breaks

15 June 2024

4

1 reference

Clustered DNA damage induced by gamma radiation in human fibroblasts (HF19), hamster (V79-4) cells and plasmid DNA is revealed as Fpg and Nth sensitive sites

15 June 2024

5

1 reference

Processing of clustered DNA damage in human breast cancer cells MCF-7 with partial DNA-PKcs deficiency.

15 June 2024

6

1 reference

Clustered DNA damages induced in human hematopoietic cells by low doses of ionizing radiation

15 June 2024

7

1 reference

Mechanism of cell killing after ionizing radiation by a dominant negative DNA polymerase beta

15 June 2024

8

1 reference

Repair of clustered uracil DNA damages in Escherichia coli

15 June 2024

9

1 reference

The mutation frequency of 8-oxo-7,8-dihydroguanine (8-oxodG) situated in a multiply damaged site: comparison of a single and two closely opposed 8-oxodG in Escherichia coli

15 June 2024

10

1 reference

Enhanced mutagenic potential of 8-oxo-7,8-dihydroguanine when present within a clustered DNA damage site

15 June 2024

11

1 reference

The roles of specific glycosylases in determining the mutagenic consequences of clustered DNA base damage

15 June 2024

12

1 reference

Two clustered 8-oxo-7,8-dihydroguanine (8-oxodG) lesions increase the point mutation frequency of 8-oxodG, but do not result in double strand breaks or deletions in Escherichia coli

15 June 2024

13

1 reference

Closely opposed apurinic/apyrimidinic sites are converted to double strand breaks in Escherichia coli even in the absence of exonuclease III, endonuclease IV, nucleotide excision repair and AP lyase cleavage

15 June 2024

14

1 reference

DNA repair of clustered lesions in mammalian cells: involvement of non-homologous end-joining

15 June 2024

15

1 reference

The formation of double-strand breaks at multiply damaged sites is driven by the kinetics of excision/incision at base damage in eukaryotic cells

15 June 2024

16

1 reference

The mechanism of human nonhomologous DNA end joining

15 June 2024

17

1 reference

The endless tale of non-homologous end-joining

15 June 2024

18

1 reference

Processing of DNA for nonhomologous end-joining is controlled by kinase activity and XRCC4/ligase IV.

15 June 2024

19

1 reference

The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit

15 June 2024

20

1 reference

Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks

15 June 2024

21

1 reference

DNA-dependent protein kinase and XRCC4-DNA ligase IV mobilization in the cell in response to DNA double strand breaks.

15 June 2024

22

1 reference

Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4

15 June 2024

23

1 reference

Accurate in vitro end joining of a DNA double strand break with partially cohesive 3'-overhangs and 3'-phosphoglycolate termini: effect of Ku on repair fidelity

15 June 2024

24

1 reference

Partial deficiency of DNA-PKcs increases ionizing radiation-induced mutagenesis and telomere instability in human cells

15 June 2024

25

1 reference

Reduced DNA-dependent protein kinase activity is associated with lung cancer

15 June 2024

26

1 reference

Roles of DNA-dependent protein kinase and ATM in cell-cycle-dependent radiation sensitivity in human cells

15 June 2024

28

1 reference

Pathways of DNA double-strand break repair during the mammalian cell cycle

15 June 2024

29

1 reference

Frameshift mutation in PRKDC, the gene for DNA-PKcs, in the DNA repair-defective, human, glioma-derived cell line M059J.

15 June 2024

32

1 reference

Focus formation of DNA repair proteins in normal and repair-deficient cells irradiated with high-LET ions

15 June 2024

34

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Repairable-conditionally repairable damage model based on dual Poisson processes

15 June 2024

35

1 reference

Dose response of gamma rays and iron nuclei for induction of chromosomal aberrations in normal and repair-deficient cell lines

15 June 2024

36

1 reference

15 June 2024

37

1 reference

Repair of DNA damage induced by accelerated heavy ions in mammalian cells proficient and deficient in the non-homologous end-joining pathway.

15 June 2024

38

1 reference

Wortmannin enhances the induction of micronuclei by low and high LET radiation.

15 June 2024

39

1 reference

A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.

15 June 2024

40

1 reference

No dose-dependence of DNA double-strand break misrejoining following alpha-particle irradiation

15 June 2024

41

1 reference

Contribution of DNA repair and cell cycle checkpoint arrest to the maintenance of genomic stability

15 June 2024

42

1 reference

The Ku-dependent non-homologous end-joining but not other repair pathway is inhibited by high linear energy transfer ionizing radiation

15 June 2024

43

1 reference

Induction and rejoining of DNA double-strand breaks in V79-4 mammalian cells following gamma- and alpha-irradiation

15 June 2024

44

1 reference

Induction and quantification of gamma-H2AX foci following low and high LET-irradiation

15 June 2024

46

1 reference

Megabase chromatin domains involved in DNA double-strand breaks in vivo

15 June 2024

47

1 reference

Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses

15 June 2024

48

1 reference

Lack of correlation between ATM protein expression and tumour cell radiosensitivity

15 June 2024

49

1 reference

Deficiency in the catalytic subunit of DNA-dependent protein kinase causes down-regulation of ATM.

15 June 2024

50

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DNA-dependent protein kinase suppresses double-strand break-induced and spontaneous homologous recombination

15 June 2024

51

1 reference

DNA-PKcs and ATM co-regulate DNA double-strand break repair

15 June 2024

52

1 reference

DNA-dependent protein kinase acts upstream of p53 in response to DNA damage

15 June 2024

54

1 reference

Processing of clustered DNA damage generates additional double-strand breaks in mammalian cells post-irradiation

15 June 2024

55

1 reference

Chemical aspects of clustered DNA damage induction by ionising radiation

15 June 2024

56

1 reference

Processing of DNA damage clusters in human cells: current status of knowledge

15 June 2024

57

1 reference

PI3K-Akt signaling regulates basal, but MAP-kinase signaling regulates radiation-induced XRCC1 expression in human tumor cells in vitro

15 June 2024

58

1 reference

XRCC1 is phosphorylated by DNA-dependent protein kinase in response to DNA damage

15 June 2024

59

1 reference

Human base excision repair complex is physically associated to DNA replication and cell cycle regulatory proteins

15 June 2024

60

1 reference

Artemis and nonhomologous end joining-independent influence of DNA-dependent protein kinase catalytic subunit on chromosome stability

15 June 2024

61

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ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation

15 June 2024

62

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Complementation of the radiosensitive M059J cell line

15 June 2024

63

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The controlling role of ATM in homologous recombinational repair of DNA damage

15 June 2024

64

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Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress

15 June 2024

65

1 reference

A role for ATR in the DNA damage-induced phosphorylation of p53

15 June 2024

66

1 reference

ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

15 June 2024

67

1 reference

Harmonising the response to DSBs: a new string in the ATM bow.

15 June 2024

68

1 reference

Biochemical kinetics model of DSB repair and induction of gamma-H2AX foci by non-homologous end joining.

15 June 2024

69

1 reference

The effects of delta rays on the number of particle-track traversals per cell in laboratory and space exposures.

15 June 2024

70

1 reference

Model for radial dependence of frequency distributions for energy imparted in nanometer volumes from HZE particles

15 June 2024

71

1 reference

15 June 2024

Identifiers

DOI

10.1667/RR2071.1

1 reference

13 September 2017

1 reference