(Q39673131)

English

Epigenetic inactivation of the tumor suppressor gene RIZ1 in hepatocellular carcinoma involves both DNA methylation and histone modifications

scientific article published on July 14, 2010

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scholarly article

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Europe PubMed Central

PubMed publication ID

13 September 2017

Epigenetic inactivation of the tumor suppressor gene RIZ1 in hepatocellular carcinoma involves both DNA methylation and histone modifications (English)

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Europe PubMed Central

PubMed publication ID

13 September 2017

DNA methylation

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hepatocellular carcinoma

1 reference

based on heuristic

inferred from title

genetic epigenesis

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20675009

14 June 2024

tumor suppressor gene

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20675009

14 June 2024

author name string

Cuijuan Zhang

1

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Europe PubMed Central

PubMed publication ID

13 September 2017

Hiuming Li

2

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Europe PubMed Central

PubMed publication ID

13 September 2017

Yan Wang

3

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Europe PubMed Central

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13 September 2017

Wenjun Liu

4

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Europe PubMed Central

PubMed publication ID

13 September 2017

Qinghui Zhang

5

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Europe PubMed Central

PubMed publication ID

13 September 2017

Tingguo Zhang

6

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Europe PubMed Central

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13 September 2017

Xiaoying Zhang

7

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Europe PubMed Central

PubMed publication ID

13 September 2017

Bo Han

8

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Europe PubMed Central

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13 September 2017

Gengyin Zhou

9

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13 September 2017

language of work or name

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publication date

14 July 2010

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13 September 2017

full work available at URL

https://api.elsevier.com/content/article/PII:S0168827810006094?httpAccept=text/xml

1 reference

10.1016/J.JHEP.2010.05.012

https://api.crossref.org/works/10.1016/J.JHEP.2010.05.012

14 June 2024

https://api.elsevier.com/content/article/PII:S0168827810006094?httpAccept=text/plain

1 reference

10.1016/J.JHEP.2010.05.012

https://api.crossref.org/works/10.1016/J.JHEP.2010.05.012

14 June 2024

Journal of Hepatology

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Europe PubMed Central

PubMed publication ID

13 September 2017

53

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Europe PubMed Central

PubMed publication ID

13 September 2017

5

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Europe PubMed Central

PubMed publication ID

13 September 2017

889-895

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Europe PubMed Central

PubMed publication ID

13 September 2017

Specific association between alcohol intake, high grade of differentiation and 4q34-q35 deletions in hepatocellular carcinomas identified by high resolution allelotyping

1

1 reference

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Down-regulation of hedgehog-interacting protein through genetic and epigenetic alterations in human hepatocellular carcinoma.

2

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Preferential loss of a polymorphic RIZ allele in human hepatocellular carcinoma.

4

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10.1016/J.JHEP.2010.05.012

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Aberrant Promoter Methylation Profiles of Tumor Suppressor Genes in Hepatocellular Carcinoma

5

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Ras pathway activation in hepatocellular carcinoma and anti-tumoral effect of combined sorafenib and rapamycin in vivo

6

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Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma.

7

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The retinoblastoma protein binds to RIZ, a zinc-finger protein that shares an epitope with the adenovirus E1A protein

8

1 reference

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RIZ1 is epigenetically inactivated by promoter hypermethylation in thyroid carcinoma.

10

1 reference

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Candidate tumor suppressor RIZ is frequently involved in colorectal carcinogenesis

11

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RIZ1 repression is associated with insulin-like growth factor-1 signaling activation in chronic myeloid leukemia cell lines

12

1 reference

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Aberrant promoter hypermethylation of multiple genes in gallbladder carcinoma and chronic cholecystitis.

13

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RIZ1 is potential CML tumor suppressor that is down-regulated during disease progression

14

1 reference

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Histone deacetylase inhibitors decrease DNA methyltransferase-3B messenger RNA stability and down-regulate de novo DNA methyltransferase activity in human endometrial cells

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Transcriptional silencing of the TMS1/ASC tumour suppressor gene by an epigenetic mechanism in hepatocellular carcinoma cells

16

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The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase

17

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DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

18

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Chromatin inactivation precedes de novo DNA methylation during the progressive epigenetic silencing of the RASSF1A promoter

19

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Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription

20

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The tumor suppressor gene DLEC1 is frequently silenced by DNA methylation in hepatocellular carcinoma and induces G1 arrest in cell cycle.

21

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Hypoxic silencing of tumor suppressor RUNX3 by histone modification in gastric cancer cells

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Transcriptional induction of DLC-1 gene through Sp1 sites by histone deacetylase inhibitors in gastric cancer cells

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High frequency of p16INK4A gene alterations in hepatocellular carcinoma

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Frequent allelic loss on chromosome 9 in hepatocellular carcinoma.

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Identifiers

10.1016/J.JHEP.2010.05.012

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

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