(Q39676137)

English

Synthesis and biological evaluation of a gamma-cyclodextrin-based formulation of the anticancer agent 5,6,11,12,17,18,23,24-octahydrocyclododeca[1,2-b:4,5-b':7,8-b'':10,11-b''']tetraindole (CTet).

scientific article published on 4 June 2010

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scholarly article

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8 February 2020

Synthesis and biological evaluation of a gamma-cyclodextrin-based formulation of the anticancer agent 5,6,11,12,17,18,23,24-octahydrocyclododeca[1,2-b:4,5-b':7,8-b'':10,11-b''']tetraindole (CTet) (English)

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8 February 2020

Simone Lucarini

1

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8 February 2020

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8 February 2020

4

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8 February 2020

Giuseppe Diamantini

5

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8 February 2020

Alessandra Fraternale

6

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8 February 2020

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Francesca Antonietti

3

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8 February 2020

Maria Filomena Paoletti

7

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8 February 2020

Andrea Tontini

8

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8 February 2020

Mauro Magnani

9

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8 February 2020

Andrea Duranti

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8 February 2020

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publication date

4 June 2010

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8 February 2020

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8 February 2020

15

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8 February 2020

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8 February 2020

4085-4093

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8 February 2020

copyright license

Creative Commons Attribution 4.0 International

4 June 2010

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April 2022 Public Data File from Crossref

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Anticarcinogenic and antioxidant activity of diindolylmethane derivatives.

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Structure elucidation of acid reaction products of indole-3-carbinol: detection in vivo and enzyme induction in vitro

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A potent indole-3-carbinol derived antitumor agent with pleiotropic effects on multiple signaling pathways in prostate cancer cells.

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A new indole-3-carbinol tetrameric derivative inhibits cyclin-dependent kinase 6 expression, and induces G1 cell cycle arrest in both estrogen-dependent and estrogen-independent breast cancer cell lines.

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Effects of immunosuppressive chemicals on lymphoid development in foetal thymus organ cultures

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12 December 2020

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Computer-aided rational drug design: a novel agent (SR13668) designed to mimic the unique anticancer mechanisms of dietary indole-3-carbinol to block Akt signaling

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The major cyclic trimeric product of indole-3-carbinol is a strong agonist of the estrogen receptor signaling pathway

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12 December 2020

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Indole-3-carbinol as a chemopreventive and anti-cancer agent

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A new class of peroxisome proliferator-activated receptor gamma (PPARgamma) agonists that inhibit growth of breast cancer cells: 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes.

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Activation of Nur77 by selected 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induces apoptosis through nuclear pathways

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https://pubmed.ncbi.nlm.nih.gov/20657428

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Enhancement of chemically-induced HL-60 cell differentiation by 3,3'-diindolylmethane derivatives

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Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20657428

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Effects of analogs of indole-3-carbinol cyclic trimerization product in human breast cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20657428

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2,3,7,8-Tetrachlorodibenzo-p-dioxin and diindolylmethanes differentially induce cytochrome P450 1A1, 1B1, and 19 in H295R human adrenocortical carcinoma cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20657428

12 December 2020

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1,1-Bis(3'-indolyl)-1-(p-chlorophenyl)methane activates the orphan nuclear receptor Nurr1 and inhibits bladder cancer growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/20657428

12 December 2020

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Synthesis and biological evaluation of fused thio- and selenopyrans as new indolocarbazole analogues with aryl hydrocarbon receptor affinity

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Novel 3,3'-diindolylmethane derivatives: synthesis and cytotoxicity, structural characterization in solid state

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https://pubmed.ncbi.nlm.nih.gov/20657428

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A novel ring-substituted diindolylmethane,1,1-bis[3'-(5-methoxyindolyl)]-1-(p-t-butylphenyl) methane, inhibits extracellular signal-regulated kinase activation and induces apoptosis in acute myelogenous leukemia

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N-Alkoxy derivatization of indole-3-carbinol increases the efficacy of the G1 cell cycle arrest and of I3C-specific regulation of cell cycle gene transcription and activity in human breast cancer cells

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Cancer chemotherapy with indole-3-carbinol, bis(3'-indolyl)methane and synthetic analogs

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Cytostatic and antiestrogenic effects of 2-(indol-3-ylmethyl)-3,3'-diindolylmethane, a major in vivo product of dietary indole-3-carbinol

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Inhibition of polycyclic aromatic hydrocarbon-induced neoplasia by naturally occurring indoles

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Identifiers

10.3390/MOLECULES15064085

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8 February 2020

1 reference

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8 February 2020

1 reference

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8 February 2020

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