(Q36174625)

English

N-Alkoxy derivatization of indole-3-carbinol increases the efficacy of the G1 cell cycle arrest and of I3C-specific regulation of cell cycle gene transcription and activity in human breast cancer cells

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scholarly article

1 reference

Europe PubMed Central

12 August 2017

N-Alkoxy derivatization of indole-3-carbinol increases the efficacy of the G1 cell cycle arrest and of I3C-specific regulation of cell cycle gene transcription and activity in human breast cancer cells (English)

1 reference

Europe PubMed Central

12 August 2017

1 reference

indole-3-carbinol

1 reference

Maria Preobrazhenskaya

object named as

Maria N Preobrazhenskaya

7

0 references

author name string

Sarah M Jump

1

1 reference

Europe PubMed Central

12 August 2017

Jenny Kung

2

1 reference

Europe PubMed Central

12 August 2017

Richard Staub

3

1 reference

Europe PubMed Central

12 August 2017

Matthew A Kinseth

4

1 reference

Europe PubMed Central

12 August 2017

Erin J Cram

5

1 reference

Europe PubMed Central

12 August 2017

Larisa N Yudina

6

1 reference

Europe PubMed Central

12 August 2017

Leonard F Bjeldanes

8

1 reference

Europe PubMed Central

12 August 2017

Gary L Firestone

9

1 reference

Europe PubMed Central

12 August 2017

language of work or name

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publication date

2 October 2007

1 reference

Europe PubMed Central

12 August 2017

full work available at URL

https://europepmc.org/articles/pmc3422660?pdf=render

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1016/j.bcp.2007.09.024?email=unpaywall_01@example.com

Biochemical Pharmacology

1 reference

Europe PubMed Central

12 August 2017

75

1 reference

Europe PubMed Central

12 August 2017

713-724

1 reference

Europe PubMed Central

12 August 2017

3

1 reference

Europe PubMed Central

12 August 2017

online access status

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1016/j.bcp.2007.09.024?email=unpaywall_01@example.com

access restriction status

1 reference

based on heuristic

inferred from online access status

Computer-aided rational drug design: a novel agent (SR13668) designed to mimic the unique anticancer mechanisms of dietary indole-3-carbinol to block Akt signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

1 October 2017

SERMs: meeting the promise of multifunctional medicines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

1 October 2017

3,3'-Diindolylmethane is a novel mitochondrial H(+)-ATP synthase inhibitor that can induce p21(Cip1/Waf1) expression by induction of oxidative stress in human breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

1 October 2017

3,3'-Diindolylmethane downregulates pro-survival pathway in hormone independent prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

1 October 2017

Molecular targets and anticancer potential of indole-3-carbinol and its derivatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

1 October 2017

Targets for indole-3-carbinol in cancer prevention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

1 October 2017

Indole-3-carbinol (I3C) inhibits cyclin-dependent kinase-2 function in human breast cancer cells by regulating the size distribution, associated cyclin E forms, and subcellular localization of the CDK2 protein complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

1 October 2017

Indole-3-carbinol and 3-3'-diindolylmethane antiproliferative signaling pathways control cell-cycle gene transcription in human breast cancer cells by regulating promoter-Sp1 transcription factor interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

1 October 2017

3,3'-Diindolylmethane (DIM) induces a G(1) cell cycle arrest in human breast cancer cells that is accompanied by Sp1-mediated activation of p21(WAF1/CIP1) expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

1 October 2017

Indole-3-carbinol inhibits CDK6 expression in human MCF-7 breast cancer cells by disrupting Sp1 transcription factor interactions with a composite element in the CDK6 gene promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

1 October 2017

The major cyclic trimeric product of indole-3-carbinol is a strong agonist of the estrogen receptor signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

1 October 2017

Indole-3-carbinol and tamoxifen cooperate to arrest the cell cycle of MCF-7 human breast cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

1 October 2017

The control of breast cancer: the role of tamoxifen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

1 October 2017

Diet intervention for modifying cancer risk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

1 October 2017

Indole-3-carbinol. A novel approach to breast cancer prevention.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

1 October 2017

Indolo[3,2-b]carbazole: a dietary-derived factor that exhibits both antiestrogenic and estrogenic activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

1 October 2017

Regulation of CYP1A1 by indolo[3,2-b]carbazole in murine hepatoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

1 October 2017

Structure-activity relationships of dietary indoles: a proposed mechanism of action as modifiers of xenobiotic metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

1 October 2017

Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

1 October 2017

Endocrine therapy for advanced breast cancer: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

1 October 2017

Inhibition of polycyclic aromatic hydrocarbon-induced neoplasia by naturally occurring indoles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

1 October 2017

Fate of indole-3-carbinol in cultured human breast tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

2 July 2018

Cytostatic and antiestrogenic effects of 2-(indol-3-ylmethyl)-3,3'-diindolylmethane, a major in vivo product of dietary indole-3-carbinol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

2 July 2018

Premenopausal breast cancer risk and intake of vegetables, fruits, and related nutrients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

2 July 2018

Effect of dietary indole-3-carbinol on intestinal and hepatic monooxygenase, glutathione S-transferase and epoxide hydrolase activities in the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

2 July 2018

Effects of indole-3-carbinol on lung tumorigenesis and DNA methylation induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and on the metabolism and disposition of NNK in A/J mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

2 July 2018

Effects of dietary indole-3-carbinol on estradiol metabolism and spontaneous mammary tumors in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

2 July 2018

Oligomerization of indole-3-carbinol in aqueous acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

2 July 2018

Indole-3-carbinol selectively uncouples expression and activity of estrogen receptor subtypes in human breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

23 September 2018

A new indole-3-carbinol tetrameric derivative inhibits cyclin-dependent kinase 6 expression, and induces G1 cell cycle arrest in both estrogen-dependent and estrogen-independent breast cancer cell lines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

23 September 2018

Bcl-2 family-mediated apoptotic effects of 3,3'-diindolylmethane (DIM) in human breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

23 September 2018

The formation of 2-hydroxy-4-hydroxymethyl-3-(indol-3-yl)-cyclopent-2-enone derivatives from ascorbigens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

23 September 2018

Indole-3-carbinol inhibits the expression of cyclin-dependent kinase-6 and induces a G1 cell cycle arrest of human breast cancer cells independent of estrogen receptor signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

23 September 2018

Chemoprevention of chemically-induced mammary carcinogenesis by indole-3-carbinol.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422660

23 September 2018

Structure elucidation of acid reaction products of indole-3-carbinol: detection in vivo and enzyme induction in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/18023427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Screening of potential chemopreventive agents using biochemical markers of carcinogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18023427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug's link to genes reveals estrogen's many sides

1 reference

https://pubmed.ncbi.nlm.nih.gov/18023427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Breast and prostate cancer: an analysis of common epidemiological, genetic, and biochemical features

1 reference

https://pubmed.ncbi.nlm.nih.gov/18023427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-methoxyindole-3-carbinol is a more efficient inducer of cytochrome P-450 1A1 in cultured cells than indol-3-carbinol

1 reference

https://pubmed.ncbi.nlm.nih.gov/18023427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.BCP.2007.09.024

1 reference

Europe PubMed Central

12 August 2017

1 reference

Europe PubMed Central

12 August 2017

1 reference

Europe PubMed Central

12 August 2017

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