(Q38363872)

English

3,3'-Diindolylmethane (DIM) induces a G(1) cell cycle arrest in human breast cancer cells that is accompanied by Sp1-mediated activation of p21(WAF1/CIP1) expression

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

3,3'-Diindolylmethane (DIM) induces a G(1) cell cycle arrest in human breast cancer cells that is accompanied by Sp1-mediated activation of p21(WAF1/CIP1) expression (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

1 reference

based on heuristic

inferred from title

author name string

Chibo Hong

1

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

Hyeon-A Kim

2

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

Gary L Firestone

3

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

Leonard F Bjeldanes

4

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

language of work or name

0 references

publication date

1 August 2002

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

23

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

1297-1305

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

Vegetables, fruit, and cancer. I. Epidemiology

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Effects of dietary indole-3-carbinol on estradiol metabolism and spontaneous mammary tumors in mice.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Selective responsiveness of human breast cancer cells to indole-3-carbinol, a chemopreventive agent.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Indole-3-carbinol inhibits the expression of cyclin-dependent kinase-6 and induces a G1 cell cycle arrest of human breast cancer cells independent of estrogen receptor signaling.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Cytostatic and antiestrogenic effects of 2-(indol-3-ylmethyl)-3,3'-diindolylmethane, a major in vivo product of dietary indole-3-carbinol

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

The major cyclic trimeric product of indole-3-carbinol is a strong agonist of the estrogen receptor signaling pathway

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Oligomerization of indole-3-carbinol in aqueous acid

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Aryl hydrocarbon receptor-mediated antiestrogenic and antitumorigenic activity of diindolylmethane

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Bcl-2 family-mediated apoptotic effects of 3,3'-diindolylmethane (DIM) in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

p21--negative regulator of the cell cycle

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Structure-activity relationships of dietary indoles: a proposed mechanism of action as modifiers of xenobiotic metabolism

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Principles of CDK regulation

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

p21 is a universal inhibitor of cyclin kinases

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Mutations in p53 as potential molecular markers for human breast cancer

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Activation of the p21WAF1/CIP1 promoter independent of p53 by the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) through the Sp1 sites

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Anchorage and growth regulation in normal and virus-transformed cells

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

G1 events and regulation of cell proliferation

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Inhibition of cyclin-dependent kinases by p21

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

p21 is a critical CDK2 regulator essential for proliferation control in Rb-deficient cells

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Proteasomal turnover of p21Cip1 does not require p21Cip1 ubiquitination

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

AKT/PKB phosphorylation of p21Cip/WAF1 enhances protein stability of p21Cip/WAF1 and promotes cell survival

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

The role of the transcription factor Sp1 in regulating the expression of the WAF1/CIP1 gene in U937 leukemic cells

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Butyrate activates the WAF1/Cip1 gene promoter through Sp1 sites in a p53-negative human colon cancer cell line

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Functional analysis of the transforming growth factor beta responsive elements in the WAF1/Cip1/p21 promoter

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Sp3 encodes multiple proteins that differ in their capacity to stimulate or repress transcription

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Histone deacetylase inhibitor activates the WAF1/Cip1 gene promoter through the Sp1 sites

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Involvement of the Sp3 transcription factor in induction of p21Cip1/WAF1 in keratinocyte differentiation

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Progesterone regulates transcription of the p21(WAF1) cyclin- dependent kinase inhibitor gene through Sp1 and CBP/p300.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Sp1 and Sp3 activate p21 (WAF1/CIP1) gene transcription in the Caco-2 colon adenocarcinoma cell line

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

O-glycosylation of eukaryotic transcription factors: implications for mechanisms of transcriptional regulation

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Modulation of transcription factor Sp1 by cAMP-dependent protein kinase.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Sp1 phosphorylation by Erk 2 stimulates DNA binding

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Activation of Sp1 and its functional co-operation with serum amyloid A-activating sequence binding factor in synoviocyte cells trigger synergistic action of interleukin-1 and interleukin-6 in serum amyloid A gene expression

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Indole-3-carbinol inhibits CDK6 expression in human MCF-7 breast cancer cells by disrupting Sp1 transcription factor interactions with a composite element in the CDK6 gene promoter

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumours

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

The p21(WAF1/CIP1) promoter is methylated in Rat-1 cells: stable restoration of p53-dependent p21(WAF1/CIP1) expression after transfection of a genomic clone containing the p21(WAF1/CIP1) gene

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Transcriptional Regulation of the p21(WAF1/CIP1)Gene

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F23.8.1297

21 January 2018

Identifiers

10.1093/CARCIN/23.8.1297

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q38363872&oldid=1756170814"