(Q39677274)

English

Single-dose treatment with a humanized neutralizing antibody affords full protection of a human transgenic mouse model from lethal Middle East respiratory syndrome (MERS)-coronavirus infection

scientific article published on 13 June 2016

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Single-dose treatment with a humanized neutralizing antibody affords full protection of a human transgenic mouse model from lethal Middle East respiratory syndrome (MERS)-coronavirus infection (English)

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Middle East respiratory syndrome coronavirus

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Middle East respiratory syndrome

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8

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Lanying Du

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

author name string

Hongjie Qiu

1

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Shihui Sun

2

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

He Xiao

3

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Jiannan Feng

4

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Yan Guo

5

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Wanbo Tai

6

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Yufei Wang

7

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Guangyu Zhao

9

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Europe PubMed Central

PMC publication ID

13 September 2017

Yusen Zhou

10

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Europe PubMed Central

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13 September 2017

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publication date

13 June 2016

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Europe PubMed Central

PMC publication ID

13 September 2017

number of pages

8

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Antiviral Research

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Europe PubMed Central

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13 September 2017

132

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

141-148

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Prophylaxis With a Middle East Respiratory Syndrome Coronavirus (MERS-CoV)-Specific Human Monoclonal Antibody Protects Rabbits From MERS-CoV Infection

1 reference

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Multi-Organ Damage in Human Dipeptidyl Peptidase 4 Transgenic Mice Infected with Middle East Respiratory Syndrome-Coronavirus

1 reference

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14 September 2017

A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein.

1 reference

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Structural basis for the neutralization of MERS-CoV by a human monoclonal antibody MERS-27

1 reference

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14 September 2017

Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus

1 reference

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14 September 2017

Pre- and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection

1 reference

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14 September 2017

Identification of an ideal adjuvant for receptor-binding domain-based subunit vaccines against Middle East respiratory syndrome coronavirus.

1 reference

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Searching for an ideal vaccine candidate among different MERS coronavirus receptor-binding fragments--the importance of immunofocusing in subunit vaccine design

1 reference

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Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp

1 reference

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Exceptionally potent neutralization of Middle East respiratory syndrome coronavirus by human monoclonal antibodies.

1 reference

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14 September 2017

Potent neutralization of MERS-CoV by human neutralizing monoclonal antibodies to the viral spike glycoprotein

1 reference

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14 September 2017

Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolution

1 reference

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14 September 2017

A conformation-dependent neutralizing monoclonal antibody specifically targeting receptor-binding domain in Middle East respiratory syndrome coronavirus spike protein.

1 reference

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14 September 2017

Preventing severe respiratory syncytial virus disease: passive, active immunisation and new antivirals.

1 reference

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14 September 2017

A truncated receptor-binding domain of MERS-CoV spike protein potently inhibits MERS-CoV infection and induces strong neutralizing antibody responses: implication for developing therapeutics and vaccines

1 reference

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14 September 2017

Virus Variation Resource--recent updates and future directions

1 reference

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14 September 2017

Wild-type and innate immune-deficient mice are not susceptible to the Middle East respiratory syndrome coronavirus

1 reference

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14 September 2017

Structure of the Fusion Core and Inhibition of Fusion by a Heptad Repeat Peptide Derived from the S Protein of Middle East Respiratory Syndrome Coronavirus

1 reference

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14 September 2017

Transmission and evolution of the Middle East respiratory syndrome coronavirus in Saudi Arabia: a descriptive genomic study

1 reference

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14 September 2017

A Unique and Conserved Neutralization Epitope in H5N1 Influenza Viruses Identified by an Antibody against the A/Goose/Guangdong/1/96 Hemagglutinin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5109928

14 September 2017

A safe and convenient pseudovirus-based inhibition assay to detect neutralizing antibodies and screen for viral entry inhibitors against the novel human coronavirus MERS-CoV

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5109928

14 September 2017

Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5109928

14 September 2017

Bilateral entry and release of Middle East respiratory syndrome coronavirus induces profound apoptosis of human bronchial epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5109928

14 September 2017

Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study Group

1 reference

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14 September 2017

Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

1 reference

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Identification and structural characterization of a broadly neutralizing antibody targeting a novel conserved epitope on the influenza virus H5N1 hemagglutinin

1 reference

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Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia

1 reference

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The spike protein of SARS-CoV--a target for vaccine and therapeutic development

1 reference

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Severe acute respiratory syndrome (SARS): a year in review.

1 reference

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1 reference

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Identification of a receptor-binding domain of the spike glycoprotein of human coronavirus HCoV-229E.

1 reference

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14 September 2017

Co-circulation of three camel coronavirus species and recombination of MERS-CoVs in Saudi Arabia

1 reference

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14 September 2017

Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26.

1 reference

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17 June 2018

Crystal structure of severe acute respiratory syndrome coronavirus spike protein fusion core

1 reference

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17 June 2018

Epidemiology and cause of severe acute respiratory syndrome (SARS) in Guangdong, People's Republic of China, in February, 2003.

1 reference

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/27312105

12 December 2020

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Identifiers

10.1016/J.ANTIVIRAL.2016.06.003

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

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