(Q39677670)

English

Phenotypic complementation establishes requirements for specific POU domain and generic transactivation function of Oct-3/4 in embryonic stem cells.

scientific article published on March 2002

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scholarly article

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7 December 2019

Phenotypic complementation establishes requirements for specific POU domain and generic transactivation function of Oct-3/4 in embryonic stem cells (English)

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7 December 2019

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7 December 2019

Jun-ichi Miyazaki

5

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7 December 2019

author name string

Hitoshi Niwa

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7 December 2019

Shinji Masui

2

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7 December 2019

Austin G Smith

4

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7 December 2019

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1 March 2002

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7 December 2019

Molecular and Cellular Biology

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7 December 2019

22

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7 December 2019

1526-1536

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7 December 2019

5

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7 December 2019

describes a project that uses

0 references

Repression of Ets-2-induced transactivation of the tau interferon promoter by Oct-4

1 reference

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14 September 2017

Molecular mechanism to maintain stem cell renewal of ES cells

1 reference

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14 September 2017

Synergism with the coactivator OBF-1 (OCA-B, BOB-1) is mediated by a specific POU dimer configuration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

Phage display screening reveals an association between germline-specific transcription factor Oct-4 and multiple cellular proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

Modulation of the activity of multiple transcriptional activation domains by the DNA binding domains mediates the synergistic action of Sox2 and Oct-3 on the fibroblast growth factor-4 enhancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

Oct-4: control of totipotency and germline determination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

The gene for the embryonic stem cell coactivator UTF1 carries a regulatory element which selectively interacts with a complex composed of Oct-3/4 and Sox-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

Synergism with germ line transcription factor Oct-4: viral oncoproteins share the ability to mimic a stem cell-specific activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

Coactivator OBF-1 makes selective contacts with both the POU-specific domain and the POU homeodomain and acts as a molecular clamp on DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal

1 reference

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14 September 2017

New POU dimer configuration mediates antagonistic control of an osteopontin preimplantation enhancer by Oct-4 and Sox-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

Rex-1, a gene encoding a transcription factor expressed in the early embryo, is regulated via Oct-3/4 and Oct-6 binding to an octamer site and a novel protein, Rox-1, binding to an adjacent site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

The carboxy-terminal transactivation domain of Oct-4 acquires cell specificity through the POU domain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

Transcriptional activation by Oct-3: evidence for a specific role of the POU-specific domain in mediating functional interaction with Oct-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

Identification of the nuclear localization signal of the POU domain protein Tst-1/Oct6

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

Germline regulatory element of Oct-4 specific for the totipotent cycle of embryonal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

The Oct-2 glutamine-rich and proline-rich activation domains can synergize with each other or duplicates of themselves to activate transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

Oct-4 transcription factor is differentially expressed in the mouse embryo during establishment of the first two extraembryonic cell lineages involved in implantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

Maintenance of an extrachromosomal plasmid vector in mouse embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

Establishment in culture of pluripotential cells from mouse embryos

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

Functional cloning of mouse chromosomal loci specifically active in embryonal carcinoma stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

How eukaryotic transcriptional activators work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

New host cell system for regulated simian virus 40 DNA replication

1 reference

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14 September 2017

Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

1 reference

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14 September 2017

Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

A family of octamer-specific proteins present during mouse embryogenesis: evidence for germline-specific expression of an Oct factor

1 reference

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Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method

1 reference

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14 September 2017

Oct-4: a germline-specific transcription factor mapping to the mouse t-complex

1 reference

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14 September 2017

A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells

1 reference

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14 September 2017

New type of POU domain in germ line-specific protein Oct-4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

Efficient selection for high-expression transfectants with a novel eukaryotic vector

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

A single amino acid exchange transfers VP16-induced positive control from the Oct-1 to the Oct-2 homeo domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

Stringent integrity requirements for both trans-activation and DNA-binding in a trans-activator, Oct3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

14 September 2017

Hybrid cell extinction and re-expression of Oct-3 function correlates with differentiation potential.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

25 September 2017

Octamer binding proteins confer transcriptional activity in early mouse embryogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

25 September 2017

Phosphorylation and DNA binding of the octamer binding transcription factor Oct-3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

25 September 2017

Identification of putative downstream genes of Oct-3, a pluripotent cell-specific transcription factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

17 June 2018

Germ-line passage is required for establishment of methylation and expression patterns of imprinted but not of nonimprinted genes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

17 June 2018

Cloning and expression of the mouse pgk-1 gene and the nucleotide sequence of its promoter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

17 June 2018

A nexus between Oct-4 and E1A: implications for gene regulation in embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

17 June 2018

Different activation domains stimulate transcription from remote ('enhancer') and proximal ('promoter') positions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

17 June 2018

Identification of a homologue of POU5F1 (OCT3/4) in a marsupial, the brushtail possum.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

21 August 2018

Mouse Lefty2 and zebrafish antivin are feedback inhibitors of nodal signaling during vertebrate gastrulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

21 August 2018

POU domain family values: flexibility, partnerships, and developmental codes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134688

21 August 2018

A cloned octamer transcription factor stimulates transcription from lymphoid–specific promoters in non–B cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11839818

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The POU domain is a bipartite DNA-binding structure

1 reference

https://pubmed.ncbi.nlm.nih.gov/11839818

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repression of the IgH enhancer in teratocarcinoma cells associated with a novel octamer factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/11839818

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.22.5.1526-1536.2002

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11839818%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11839818%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11839818%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

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