(Q39679973)

13 September 2017

title

Sorafenib and Quinacrine Target Anti-Apoptotic Protein MCL1: A Poor Prognostic Marker in Anaplastic Thyroid Cancer (ATC). (English)

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anaplastic thyroid cancer

13 September 2017

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1 reference

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27307592%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Wafik El-Deiry

12

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8 June 2020

author name string

Junaid Abdulghani

1

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8 June 2020

Prashanth Gokare

2

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8 June 2020

David Dicker

4

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8 June 2020

Tiffany Whitcomb

5

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8 June 2020

Timothy Cooper

6

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8 June 2020

Jiangang Liao

7

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8 June 2020

Jonathan Derr

8

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8 June 2020

Jing Liu

9

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8 June 2020

David Goldenberg

10

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8 June 2020

Niklas K Finnberg

11

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8 June 2020

language of work or name

English

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publication date

15 June 2016

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13 September 2017

published in

Clinical Cancer Research

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8 June 2020

volume

22

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8 June 2020

issue

24

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8 June 2020

page(s)

6192-6203

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Anaplastic thyroid cancer: outcome and the mutation/expression profiles of potential targets.

8 June 2020

cites work

1 reference

12 December 2020

Detailed molecular fingerprinting of four new anaplastic thyroid carcinoma cell lines and their use for verification of RhoB as a molecular therapeutic target

1 reference

12 December 2020

Anaplastic thyroid cancer: molecular pathogenesis and emerging therapies

1 reference

12 December 2020

A cell proliferation and chromosomal instability signature in anaplastic thyroid carcinoma.

1 reference

12 December 2020

Regulation of Mcl-1 by constitutive activation of NF-κB contributes to cell viability in human esophageal squamous cell carcinoma cells

1 reference

12 December 2020

Sorafenib in metastatic thyroid cancer: a systematic review

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12 December 2020

Anaplastic thyroid cancer: a review of epidemiology, pathogenesis, and treatment

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12 December 2020

Delineation, functional validation, and bioinformatic evaluation of gene expression in thyroid follicular carcinomas with the PAX8-PPARG translocation.

1 reference

12 December 2020

Phase II trial of sorafenib in patients with advanced anaplastic carcinoma of the thyroid.

1 reference

12 December 2020

Small molecules that reactivate p53 in renal cell carcinoma reveal a NF-kappaB-dependent mechanism of p53 suppression in tumors

1 reference

12 December 2020

Quinacrine synergistically enhances the antivascular and antitumor efficacy of cediranib in intracranial mouse glioma

1 reference

12 December 2020

A small-molecule triptolide suppresses angiogenesis and invasion of human anaplastic thyroid carcinoma cells via down-regulation of the nuclear factor-kappa B pathway

1 reference

12 December 2020

Immunohistochemical and sequencing analyses of the Wnt signaling components in Japanese anaplastic thyroid cancers.

1 reference

12 December 2020

Targeted therapy of VEGFR2 and EGFR significantly inhibits growth of anaplastic thyroid cancer in an orthotopic murine model.

1 reference

12 December 2020

Sorafenib in advanced hepatocellular carcinoma

1 reference

12 December 2020

The Role of Survivin in Thyroid Tumors: Differences of Expression in Well-Differentiated, Non–Well-Differentiated, and Anaplastic Thyroid Cancers

1 reference

12 December 2020

Preclinical overview of sorafenib, a multikinase inhibitor that targets both Raf and VEGF and PDGF receptor tyrosine kinase signaling

1 reference

12 December 2020

Mcl-1 expression predicts progression-free survival in chronic lymphocytic leukemia patients treated with pentostatin, cyclophosphamide, and rituximab

1 reference

12 December 2020

Aberrant rel/nfkb genes and activity in human cancer

1 reference

12 December 2020

STAT3 negatively regulates thyroid tumorigenesis

1 reference

12 December 2020

Morphoproteomic confirmation of an activated nuclear factor-кBp65 pathway in follicular thyroid carcinoma

1 reference

12 December 2020

Survival of a patient with anaplastic thyroid cancer following intensity-modulated radiotherapy and sunitinib--a case report.

1 reference

12 December 2020

An orthotopic model of anaplastic thyroid carcinoma in athymic nude mice.

1 reference

12 December 2020

Stat3 promotes metastatic progression of prostate cancer.

1 reference

12 December 2020

Immunohistochemical detection of epithelialmesenchymal transition associated with stemness phenotype in anaplastic thyroid carcinoma

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12 December 2020

Poorly differentiated and anaplastic thyroid cancer

1 reference

12 December 2020

Establishment of 2 human thyroid-carcinoma cell-lines (8305c, 8505c) bearing p53 gene-mutations.

1 reference

12 December 2020

Oncogenic and anti-apoptotic activity of NF-kappa B in human thyroid carcinomas

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12 December 2020

Patterns of expression of cell cycle/apoptosis genes along the spectrum of thyroid carcinoma progression

1 reference

12 December 2020

Reduction of TRAIL-induced Mcl-1 and cIAP2 by c-Myc or sorafenib sensitizes resistant human cancer cells to TRAIL-induced death.

1 reference

12 December 2020

Mcl-1 ubiquitination: unique regulation of an essential survival protein

1 reference

12 December 2020

Quinacrine synergizes with 5-fluorouracil and other therapies in colorectal cancer

1 reference

12 December 2020

Quinacrine sensitizes hepatocellular carcinoma cells to TRAIL and chemotherapeutic agents.

1 reference

12 December 2020

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

1 reference

12 December 2020

Antitumor effects of the proteasome inhibitor bortezomib in medullary and anaplastic thyroid carcinoma cells in vitro

1 reference

12 December 2020

Sorafenib in radioactive iodine-refractory, locally advanced or metastatic differentiated thyroid cancer: a randomised, double-blind, phase 3 trial

1 reference

12 December 2020

Sorafenib sensitizes solid tumors to Apo2L/TRAIL and Apo2L/TRAIL receptor agonist antibodies by the Jak2-Stat3-Mcl1 axis

1 reference

12 December 2020

Deoxyribonucleic acid profiling analysis of 40 human thyroid cancer cell lines reveals cross-contamination resulting in cell line redundancy and misidentification

1 reference

12 December 2020

New therapeutic advances in the management of progressive thyroid cancer

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12 December 2020

Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies

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12 December 2020

Beyond DNA binding - a review of the potential mechanisms mediating quinacrine's therapeutic activities in parasitic infections, inflammation, and cancers

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12 December 2020

Imatinib enhances docetaxel-induced apoptosis through inhibition of nuclear factor-κB activation in anaplastic thyroid carcinoma cells

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12 December 2020

Dehydroxymethylepoxyquinomicin, a novel nuclear Factor-kappaB inhibitor, enhances antitumor activity of taxanes in anaplastic thyroid cancer cells.

1 reference

12 December 2020

Sorafenib in advanced clear-cell renal-cell carcinoma

1 reference

12 December 2020

NGAL controls the metastatic potential of anaplastic thyroid carcinoma cells.

1 reference

12 December 2020

Phase II trial of sorafenib in advanced thyroid cancer

1 reference

12 December 2020

mRNA expression in papillary and anaplastic thyroid carcinoma: molecular anatomy of a killing switch

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12 December 2020

The tyrosine kinase inhibitor, AZD2171, inhibits vascular endothelial growth factor receptor signaling and growth of anaplastic thyroid cancer in an orthotopic nude mouse model

1 reference

12 December 2020

CRAF inhibition induces apoptosis in melanoma cells with non-V600E BRAF mutations

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12 December 2020

Expression of the cell death-inducing gene bax in carcinomas developed from the follicular cells of the thyroid gland

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12 December 2020

Immunohistochemical analysis of Mcl-1 protein in human tissues. Differential regulation of Mcl-1 and Bcl-2 protein production suggests a unique role for Mcl-1 in control of programmed cell death in vivo.

1 reference

12 December 2020

10.1158/1078-0432.CCR-15-2792

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27307592%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

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