(Q33227187)

24 July 2017

title

Small molecules that reactivate p53 in renal cell carcinoma reveal a NF-kappaB-dependent mechanism of p53 suppression in tumors (English)

1 reference

24 July 2017

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1 reference

Andrei V Gudkov

15

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Jason Hill

1 reference

ORCID Public Data File 2021

author name string

Katerina V Gurova

1

1 reference

24 July 2017

Jason E Hill

2

1 reference

24 July 2017

Canhui Guo

3

1 reference

24 July 2017

Anatoly Prokvolit

4

1 reference

24 July 2017

Lyudmila G Burdelya

5

1 reference

24 July 2017

Eugenia Samoylova

6

1 reference

24 July 2017

Anna V Khodyakova

7

1 reference

24 July 2017

Ram Ganapathi

8

1 reference

24 July 2017

Mahrukh Ganapathi

9

1 reference

24 July 2017

Natalia D Tararova

10

1 reference

24 July 2017

Dmitry Bosykh

11

1 reference

24 July 2017

Dmitriy Lvovskiy

12

1 reference

24 July 2017

Thomas R Webb

13

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24 July 2017

George R Stark

14

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24 July 2017

language of work or name

English

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publication date

15 November 2005

1 reference

Proceedings of the National Academy of Sciences of the United States of America

24 July 2017

published in

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24 July 2017

volume

102

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24 July 2017

issue

48

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24 July 2017

page(s)

17448-17453

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Phosphorylation of NF-kappaB and IkappaB proteins: implications in cancer and inflammation

24 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297696

Setting the stage for transformation: HTLV-1 Tax inhibition of p53 function

14 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297696

14 July 2018

https://api.crossref.org/works/10.1073%2FPNAS.0508888102

Nuclear factor-kappaB modulation as a therapeutic approach in hematologic malignancies

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297696

TP53 mutation spectra and load: a tool for generating hypotheses on the etiology of cancer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297696

Role of NF-kappa B in cell survival and transcription of latent membrane protein 1-expressing or Epstein-Barr virus latency III-infected cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297696

The IKK/NF-kappaB activation pathway-a target for prevention and treatment of cancer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297696

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297696

Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297696

Clinical update: proteasome inhibitors in solid tumors

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297696

Inhibition of constitutive NF-kappa B activity by I kappa B alpha M suppresses tumorigenesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297696

Usage of the NF-kappaB inhibitor sulfasalazine as sensitizing agent in combined chemotherapy of pancreatic cancer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297696

Dominant negative form of signal-regulatory protein-alpha (SIRPalpha /SHPS-1) inhibits tumor necrosis factor-mediated apoptosis by activation of NF-kappa B.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297696

NF-kappaB inhibits transcription of the H(+)-K(+)-ATPase alpha(2)-subunit gene: role of histone deacetylases

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297696

IKKalpha, IKKbeta, and NEMO/IKKgamma are each required for the NF-kappa B-mediated inflammatory response program.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297696

NF-kappaB as a therapeutic target in cancer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297696

High-throughput measurement of the Tp53 response to anticancer drugs and random compounds using a stably integrated Tp53-responsive luciferase reporter

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297696

The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297696

Constitutive activation of nuclear factor-kappaB prevents TRAIL-induced apoptosis in renal cancer cells.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297696

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297696

Transcriptional cross talk between NF-kappaB and p53.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297696

Effect of quinacrine, a phospholipase A2 inhibitor on stress and chemically induced gastroduodenal ulcers

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297696

Critical role for lysines 21 and 22 in signal-induced, ubiquitin-mediated proteolysis of I kappa B-alpha

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297696

The use of quinacrine (Atabrine) in rheumatic diseases: a reexamination

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297696

Characterization of an amsacrine-resistant line of human leukemia cells. Evidence for a drug-resistant form of topoisomerase II.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297696

p53 pathway in renal cell carcinoma is repressed by a dominant mechanism.

14 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0508888102

Increased nuclear factor-kappa B activation is related to the tumor development of renal cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0508888102

Loss of nuclear factor-kappaB is tumor promoting but does not substitute for loss of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0508888102

Capsaicin exhibits anti-inflammatory property by inhibiting IkB-a degradation in LPS-stimulated peritoneal macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0508888102

IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0508888102

21 January 2018

Identifiers

DOI

10.1073/PNAS.0508888102

1 reference

24 July 2017

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24 July 2017

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