(Q39683291)

English

Mutations that confer resistance to template-analog inhibitors of human immunodeficiency virus (HIV) type 1 reverse transcriptase lead to severe defects in HIV replication

scientific article published on April 2002

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Mutations that confer resistance to template-analog inhibitors of human immunodeficiency virus (HIV) type 1 reverse transcriptase lead to severe defects in HIV replication (English)

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Vinayaka R. Prasad

object named as

Vinayaka R Prasad

3

0 references

author name string

Timothy S Fisher

1

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Pheroze Joshi

2

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

language of work or name

0 references

publication date

1 April 2002

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Journal of Virology

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

76

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

8

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

4068-4072

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

HIV-1 reverse transcriptase-pseudoknot RNA aptamer interaction has a binding affinity in the low picomolar range coupled with high specificity

1 reference

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Gene therapy using SV40-derived vectors: what does the future hold?

1 reference

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Decreased processivity of human immunodeficiency virus type 1 reverse transcriptase (RT) containing didanosine-selected mutation Leu74Val: a comparative analysis of RT variants Leu74Val and lamivudine-selected Met184Val.

1 reference

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Liposome-mediated delivery of antiviral agents to human immunodeficiency virus-infected cells

1 reference

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Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 A resolution

1 reference

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Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

1 reference

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Human immunodeficiency virus replication and genotypic resistance in blood and lymph nodes after a year of potent antiretroviral therapy

1 reference

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Phosphorothioate oligonucleotides derived from human immunodeficiency virus type 1 (HIV-1) primer tRNALys3 are strong inhibitors of HIV-1 reverse transcriptase and arrest viral replication in infected cells

1 reference

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Inhibition of HIV-1 replication using a mutated tRNALys-3 primer

1 reference

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A high affinity binding site for the HIV-1 nucleocapsid protein

1 reference

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Transduction of human CD34+ hematopoietic progenitor cells by a retroviral vector expressing an RRE decoy inhibits human immunodeficiency virus type 1 replication in myelomonocytic cells produced in long-term culture

1 reference

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Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme.

1 reference

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SETOR: hardware-lighted three-dimensional solid model representations of macromolecules

1 reference

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Characterization of an in vitro-selected RNA ligand to the HIV-1 Rev protein

1 reference

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Isolation of high-affinity RNA ligands to HIV-1 integrase from a random pool

1 reference

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Sequence-specific inhibition of human immunodeficiency virus (HIV) reverse transcription by antisense oligonucleotides: comparative study in cell-free assays and in HIV-infected cells

1 reference

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High-affinity ssDNA inhibitors of the reverse transcriptase of type 1 human immunodeficiency virus

1 reference

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Selection of high-affinity RNA ligands to reverse transcriptase: inhibition of cDNA synthesis and RNase H activity

1 reference

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Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase

1 reference

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14 September 2017

Isolation and characterization of a dideoxyguanosine triphosphate-resistant mutant of human immunodeficiency virus reverse transcriptase

1 reference

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14 September 2017

RNA pseudoknots that inhibit human immunodeficiency virus type 1 reverse transcriptase

1 reference

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14 September 2017

The structure of HIV-1 reverse transcriptase complexed with an RNA pseudoknot inhibitor

1 reference

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17 June 2018

Selection and design of high-affinity RNA ligands for HIV-1 Rev.

1 reference

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17 June 2018

A novel in situ colony screening method to detect human immunodeficiency virus reverse transcriptase activity expressed in bacteria. Isolation of pseudorevertants of reverse transcriptase mutants.

1 reference

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A clinical trial of retroviral-mediated transfer of a rev-responsive element decoy gene into CD34(+) cells from the bone marrow of human immunodeficiency virus-1-infected children.

1 reference

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Receptor ligand-facilitated cationic liposome delivery of anti-HIV-1 Rev-binding aptamer and ribozyme DNAs.

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Inhibitory RNA ligand to reverse transcriptase from feline immunodeficiency virus

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Reduced frameshift fidelity and processivity of HIV-1 reverse transcriptase mutants containing alanine substitutions in helix H of the thumb subdomain.

1 reference

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Structure/function studies of human immunodeficiency virus type 1 reverse transcriptase. Alanine scanning mutagenesis of an alpha-helix in the thumb subdomain

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Subunit-selective mutagenesis of Glu-89 residue in human immunodeficiency virus reverse transcriptase. Contribution of p66 and p51 subunits to nucleoside analog sensitivity, divalent cation preference, and steady state kinetic properties.

1 reference

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Structural requirements for bacterial expression of stable, enzymatically active fusion proteins containing the human immunodeficiency virus reverse transcriptase

1 reference

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In vitro evolution of functional nucleic acids: high-affinity RNA ligands of HIV-1 proteins

1 reference

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A minor groove binding track in reverse transcriptase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11907245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aptamers as therapeutic and diagnostic reagents: problems and prospects

1 reference

https://pubmed.ncbi.nlm.nih.gov/11907245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.76.8.4068-4072.2002

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

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