(Q39684126)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20603613%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

Inhibition of GLI, but not Smoothened, induces apoptosis in chronic lymphocytic leukemia cells (English)

1 reference

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7 February 2020

0 references

1 reference

chronic lymphocytic leukemia

1 reference

11

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7 February 2020

Tanja N Hartmann

12

1 reference

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7 February 2020

Tanja N Hartmann

13

1 reference

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7 February 2020

author name string

P Desch

1

1 reference

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7 February 2020

D Asslaber

2

1 reference

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7 February 2020

D Kern

3

1 reference

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7 February 2020

H Schnidar

4

1 reference

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7 February 2020

D Mangelberger

5

1 reference

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7 February 2020

B Alinger

6

1 reference

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7 February 2020

M Stoecher

7

1 reference

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7 February 2020

S W Hofbauer

8

1 reference

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7 February 2020

D Neureiter

9

1 reference

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7 February 2020

I Tinhofer

10

1 reference

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7 February 2020

R Greil

14

1 reference

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7 February 2020

language of work or name

English

0 references

publication date

5 July 2010

1 reference

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7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20603613%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

volume

29

1 reference

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7 February 2020

issue

35

1 reference

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7 February 2020

page(s)

4885-4895

1 reference

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https://scigraph.springernature.com/pub.10.1038/onc.2010.243

7 February 2020

exact match

0 references

cites work

Sonic hedgehog promotes cell cycle progression in activated peripheral CD4(+) T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells

21 January 2018

1 reference

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Sonic hedgehog is produced by follicular dendritic cells and protects germinal center B cells from apoptosis.

21 January 2018

1 reference

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Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

Small peptide inhibitors of the CXCR4 chemokine receptor (CD184) antagonize the activation, migration, and antiapoptotic responses of CXCL12 in chronic lymphocytic leukemia B cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

Role of the microenvironment in chronic lymphocytic leukaemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

Small molecule modulation of Smoothened activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

Chronic lymphocytic leukemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

Induction of sonic hedgehog mediators by transforming growth factor-beta: Smad3-dependent activation of Gli2 and Gli1 expression in vitro and in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

Expansion of Bcr-Abl-positive leukemic stem cells is dependent on Hedgehog pathway activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

Essential role of stromally induced hedgehog signaling in B-cell malignancies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

Genomic aberrations and survival in chronic lymphocytic leukemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

Chromosome aberrations in B-cell chronic lymphocytic leukemia: reassessment based on molecular cytogenetic analysis

31 March 2020

1 reference

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Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin E.

31 March 2020

1 reference

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Cyclopamine treatment of full-blown Hh/Ptch-associated RMS partially inhibits Hh/Ptch signaling, but not tumor growth

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells

31 March 2020

1 reference

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Hedgehog signaling is dispensable for adult hematopoietic stem cell function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

The world according to hedgehog

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

Hedgehog-induced survival of B-cell chronic lymphocytic leukemia cells in a stromal cell microenvironment: a potential new therapeutic target

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

Hedgehog signaling is dispensable for adult murine hematopoietic stem cell function and hematopoiesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

GLI2 is expressed in normal human epidermis and BCC and induces GLI1 expression by binding to its promoter

31 March 2020

1 reference

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Hedgehog signaling in animal development: paradigms and principles

31 March 2020

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Rho inhibition induces migration of mesenchymal stromal cells

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.243

Oncogenic KRAS activates hedgehog signaling pathway in pancreatic cancer cells

31 March 2020

1 reference

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Hedgehog signalling in prostate regeneration, neoplasia and metastasis

31 March 2020

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Efficient manipulation of Hedgehog/GLI signaling using retroviral expression systems.

31 March 2020

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Trisomy 12 in B cells of patients with B-cell chronic lymphocytic leukemia

31 March 2020

1 reference

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Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

Phorbol esters inhibit the Hedgehog signalling pathway downstream of Suppressor of Fused, but upstream of Gli.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

Stroma-initiated hedgehog signaling takes center stage in B-cell lymphoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

Regulation of patched by sonic hedgehog in the developing neural tube

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

Medulloblastoma: developmental mechanisms out of control

31 March 2020

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Comparison of SYBR Green I and TaqMan real-time PCR formats for the analysis of her2 gene dose in human breast tumors

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.243

Mutations affecting segment number and polarity in Drosophila

31 March 2020

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Basal cell carcinomas in mice overexpressing sonic hedgehog

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

Human bone marrow stromal cells prevent apoptosis and support the survival of chronic lymphocytic leukaemia cells in vitro

31 March 2020

1 reference

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CD38 expression in chronic lymphocytic leukemia is regulated by the tumor microenvironment

31 March 2020

1 reference

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Hedgehog signaling maintains a tumor stem cell compartment in multiple myeloma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

Molecular and cellular mechanisms of CLL: novel therapeutic approaches.

31 March 2020

1 reference

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Human GLI2 and GLI1 are part of a positive feedback mechanism in Basal Cell Carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

Protein kinase C-delta and mitogen-activated protein/extracellular signal-regulated kinase-1 control GLI activation in hedgehog signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice.

31 March 2020

1 reference

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Efficient nucleofection of primary human B cells and B-CLL cells induces apoptosis, which depends on the microenvironment and on the structure of transfected nucleic acids

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

CXCR4 antagonist inhibits stromal cell-derived factor 1-induced migration and invasion of human pancreatic cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

MEC1 and MEC2: two new cell lines derived from B-chronic lymphocytic leukaemia in prolymphocytoid transformation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

Evidence for the direct involvement of {beta}TrCP in Gli3 protein processing

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

A paracrine requirement for hedgehog signalling in cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

ZAP-70 expression, as detected by immunohistochemistry on bone marrow biopsies from early-phase CLL patients, is a strong adverse prognostic factor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.243

31 March 2020

Identifiers

DOI

10.1038/ONC.2010.243

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20603613%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference