(Q39687825)

English

Ganglioside GD3 enhances adhesion signals and augments malignant properties of melanoma cells by recruiting integrins to glycolipid-enriched microdomains

scientific article published on 25 June 2010

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Ganglioside GD3 enhances adhesion signals and augments malignant properties of melanoma cells by recruiting integrins to glycolipid-enriched microdomains (English)

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

author name string

Yuki Ohkawa

1

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Sayaka Miyazaki

2

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Kazunori Hamamura

3

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Mariko Kambe

4

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Maiko Miyata

5

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Orie Tajima

6

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Yuhsuke Ohmi

7

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Yoshio Yamauchi

8

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Koichi Furukawa

9

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Keiko Furukawa

10

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

language of work or name

0 references

publication date

25 June 2010

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

285

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

35

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

27213-27223

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Cross-talk among integrin, cadherin, and growth factor receptor: roles of nectin and nectin-like molecule.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

14 September 2017

Focal adhesion kinase as a regulator of cell tension in the progression of cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

14 September 2017

Integrin-regulated FAK-Src signaling in normal and cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

14 September 2017

Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

14 September 2017

Integrins adhesion molecules and some of their ligands in laryngeal cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

14 September 2017

Integrin signaling in malignant melanoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

14 September 2017

Interruption of ganglioside synthesis produces central nervous system degeneration and altered axon-glial interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

14 September 2017

The role of integrin-linked kinase (ILK) in cancer progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

14 September 2017

Gangliosides as therapeutic targets for cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

14 September 2017

Lipid rafts and signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

14 September 2017

Drosophila integrin-linked kinase is required at sites of integrin adhesion to link the cytoskeleton to the plasma membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

14 September 2017

Carbohydrate-carbohydrate binding of ganglioside to integrin alpha(5) modulates alpha(5)beta(1) function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

14 September 2017

Paxillin interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

14 September 2017

The role of membrane lipids in regulation of integrin functions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

14 September 2017

Cellular gangliosides promote growth factor-induced proliferation of fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

14 September 2017

FAK integrates growth-factor and integrin signals to promote cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

14 September 2017

Integrins and actin filaments: reciprocal regulation of cell adhesion and signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

14 September 2017

Integrin signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

14 September 2017

Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

14 September 2017

Nerve growth factor stimulates the tyrosine phosphorylation of endogenous Crk-II and augments its association with p130Cas in PC-12 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

14 September 2017

Isolation of GD3 synthase gene by expression cloning of GM3 alpha-2,8-sialyltransferase cDNA using anti-GD2 monoclonal antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

14 September 2017

Focal adhesion kinase and associated proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

14 September 2017

Collagens: molecular biology, diseases, and potentials for therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

14 September 2017

Mouse monoclonal IgG3 antibody detecting GD3 ganglioside: a phase I trial in patients with malignant melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

14 September 2017

Disialogangliosides GD2 and GD3 are involved in the attachment of human melanoma and neuroblastoma cells to extracellular matrix proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

14 September 2017

Essential roles of integrin-mediated signaling for the enhancement of malignant properties of melanomas based on the expression of GD3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

14 September 2017

Focal adhesion kinase as well as p130Cas and paxillin is crucially involved in the enhanced malignant properties under expression of ganglioside GD3 in melanoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

14 September 2017

CD24 induces localization of beta1 integrin to lipid raft domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

14 September 2017

The role of integrin-linked kinase in melanoma cell migration, invasion, and tumor growth.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

14 September 2017

Ganglioside G(D2) in small cell lung cancer cell lines: enhancement of cell proliferation and mediation of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

25 September 2017

Biologic roles of gangliosides G(M3) and G(D3) in the attachment of human melanoma cells to extracellular matrix proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

25 September 2017

Cell migration strategies in 3-D extracellular matrix: differences in morphology, cell matrix interactions, and integrin function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

25 September 2017

Gangliosides and glycosphingolipids as modulators of cell growth, adhesion, and transmembrane signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

25 September 2017

Human melanoma cell lines deficient in GD3 ganglioside expression exhibit altered growth and tumorigenic characteristics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

25 September 2017

Signaling through focal adhesion kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

25 September 2017

Melanoma Growth Stimulatory Activity Signaling through the Class II Interleukin-8 Receptor Enhances the Tyrosine Phosphorylation of Crk-Associated Substrate, p130, and a 70-Kilodalton Protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

25 September 2017

Integrin-mediated cell adhesion promotes tyrosine phosphorylation of p130Cas, a Src homology 3-containing molecule having multiple Src homology 2-binding motifs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

25 September 2017

Variants of BALB/c 3T3 cells lacking complex gangliosides retain a fibronectin matrix and spread normally on fibronectin-coated substrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

15 June 2018

Inhibition of metastases of a human melanoma xenograft by monoclonal antibody to the GD2/GD3 gangliosides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

15 June 2018

Lipid Composition of Human Malignant Melanoma Tumors at Various Levels of Malignant Growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

15 June 2018

Effect of ganglioside and tetraspanins in microdomains on interaction of integrins with fibroblast growth factor receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

20 August 2018

Roles of lipid rafts in integrin-dependent adhesion and gp130 signalling pathway in mouse embryonic neural precursor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

20 August 2018

Sensitization of epidermal growth factor-induced signaling by bradykinin is mediated by c-Src. Implications for a role of lipid microdomains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

20 August 2018

Suppression of lung metastasis of mouse Lewis lung cancer P29 with transfection of the ganglioside GM2/GD2 synthase gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

20 August 2018

The Integrins α3β1and α6β1 Physically and Functionally Associate with CD36 in Human Melanoma Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930720

2 December 2018

Tumor gangliosides enhance alpha2 beta1 integrin-dependent platelet activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20581115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of neuroblastoma tumor gangliosides on platelet adhesion to collagen

1 reference

https://pubmed.ncbi.nlm.nih.gov/20581115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signaling reactions induced in human fibroblasts during adhesion to cementum-derived attachment protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/20581115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Atherosclerotic aortic gangliosides enhance integrin-mediated platelet adhesion to collagen

1 reference

https://pubmed.ncbi.nlm.nih.gov/20581115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phase I study of an anti-GD3 monoclonal antibody, KW-2871, in patients with metastatic melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20581115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Refractory skin injury in complex knock-out mice expressing only the GM3 ganglioside

1 reference

https://pubmed.ncbi.nlm.nih.gov/20581115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of melanoma tumor growth by a novel inhibitor of glucosylceramide synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/20581115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of human melanoma cell growth in vitro by monoclonal anti-GD3-ganglioside antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/20581115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gangliosides of normal and neoplastic human melanocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20581115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M109.087791

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

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