(Q39690028)

14 September 2017

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title

Propafenone. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in the treatment of arrhythmias (English)

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14 September 2017

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2

R N Brogden

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14 September 2017

D W Harron

1

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14 September 2017

1 December 1987

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14 September 2017

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14 September 2017

34

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14 September 2017

6

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14 September 2017

617-647

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https://scigraph.springernature.com/pub.10.2165/00003495-198734060-00001

14 September 2017

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cites work

Limited role of intravenous propafenone hydrochloride in the treatment of sustained ventricular tachycardia: Electrophysiologic effects and results of programmed ventricular stimulation

1 reference

12 December 2020

European experience with the antiarrhythmic efficacy of propafenone for supraventricular and ventricular arrhythmias

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12 December 2020

Correlation between serum concentration and pharmacological effect on atrioventricular conduction time of the antiarrhythmic drug propafenone

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12 December 2020

Comparison of two methods of analyzing frequency of ventricular arrhythmias

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12 December 2020

Cholestasis after antiarrhythmic therapy with propafenone

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12 December 2020

Pharmacology of 2'-[2-hydroxy-3-(propylamino)-propoxy]-3-phenylpropiophenone (Propafenone, SA 79)-hydrochloride

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12 December 2020

Demonstration of beta adrenoceptor blockade by propafenone hydrochloride: clinical pharmacologic, radioligand binding and adenylate cyclase activation studies

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12 December 2020

Propafenone disposition kinetics in cardiac arrhythmia

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12 December 2020

Metabolite cumulation during chronic propafenone dosing in arrhythmia.

1 reference

12 December 2020

[Idiopathic ventricular tachyarrhythmia. Spontaneous variability and effect of various antiarrhythmic agents]

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12 December 2020

Comparison of propafenone and disopyramide for treatment of chronic ventricular arrhythmias: placebo-controlled, double-blind, randomized crossover study

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12 December 2020

Determination of plasma protein binding of propafenone in rats, dogs and humans by highly sensitive gas chromatography-mass spectrometry

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12 December 2020

Electrophysiological and Antiarrhythmic Properties of Propafenon in Isolated Cardiac Preparations

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12 December 2020

Limitations of routine long-term electrocardiographic monitoring to assess ventricular ectopic frequency

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12 December 2020

Double-blind placebo-controlled evaluation of propafenone in suppressing ventricular ectopic activity

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12 December 2020

Distribution of propafenone and its active metabolite, 5-hydroxypropafenone, in human tissues

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12 December 2020

Electrophysiological effects of propafenone on isolated guinea-pig ventricular muscle and sheep Purkinje fibres

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12 December 2020

Polymorphism of propafenone metabolism and disposition in man: clinical and pharmacokinetic consequences

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12 December 2020

Therapy of ventricular tachyarrhythmias refractory to lidocaine with propafenone (author's transl)

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12 December 2020

Effects of Propafenone on Induction and Maintenance of Atrioventricular Nodal Reentrant Tachycardia

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12 December 2020

Double-blind study of intravenous propafenone for paroxysmal supraventricular reentrant tachycardia

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12 December 2020

Influence of protein binding on the myocardial uptake and pharmacodynamics of propafenone

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12 December 2020

[Profound granulocytopenia in a patient treated with propafenon ]

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12 December 2020

Food increases the bioavailability of propafenone

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12 December 2020

Electrophysiologic effects of propafenone

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12 December 2020

Electrophysiologic and hemodynamic effects of intravenous propafenone in patients with recurrent ventricular tachycardia

1 reference

12 December 2020

[Efficacy and tolerance of propafenone in the treatment of cardiac rhythm disorders. Evaluation of a multicenter open trial on 3,687 patients]

1 reference

12 December 2020

The multiple modes of action of propafenone

1 reference

12 December 2020

Antiarrhythmic efficacy of propafenone: evaluation of effective plasma levels following single and multiple doses

1 reference

12 December 2020

Extracardiac adverse effects of flecainide

1 reference

12 December 2020

Interaction between warfarin and propafenone in healthy volunteer subjects

1 reference

12 December 2020

Propafenone and a syndrome of the lupus erythematosus type

1 reference

12 December 2020

Intravenous propafenone for termination of reentrant supraventricular tachycardia. A placebo-controlled, randomized, double-blind, crossover study

1 reference

12 December 2020

Propafenone--a new antiarrhythmic drug

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12 December 2020

[Therapy of severe propafenone poisoning--an attempt at elimination by hemoperfusion]

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12 December 2020

Electrophysiologic effects of propafenone on canine ischemic cardiac cells

1 reference

12 December 2020

Electrophysiological effects of propafenone studied with programmed electrical stimulation of the heart in patients with recurrent paroxysmal supraventricular tachycardia

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12 December 2020

Propafenone: a new agent for ventricular arrhythmia

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12 December 2020

Comparative investigation of the antiarrhythmic effect of propafenone (Rytmonorm) and lidocaine in patients with ventricular arrhythmias during acute myocardial infarction.

1 reference

12 December 2020

Combined use of propafenon and lidoflazine in chronic atrial fibrillation and flutter (author's transl)

1 reference

12 December 2020

Enhanced antiarrhythmic efficacy of propafenone when used in combination with procainamide or quinidine.

1 reference

12 December 2020

[The effect of anti-arrhythmic drugs on myocardial function (author's transl)]

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12 December 2020

Efficacy of propafenone in Wolff-Parkinson-White syndrome: electrophysiologic findings and long-term follow-up

1 reference

12 December 2020

Electrophysiologic and hemodynamic effects of propafenone, a new antiarrhythmic agent, on the anesthetized, closed-chest dog: comparative study with lidocaine.

1 reference

12 December 2020

Suppression of ventricular arrhythmias by propafenone, a new antiarrhythmic agent, during acute myocardial infarction in the conscious dog. A comparative study with lidocaine.

1 reference

12 December 2020

Electrophysiologic effects and clinical efficacy of oral propafenone therapy in patients with ventricular tachycardia

1 reference

12 December 2020

Effectiveness of increasing hours of continuous ambulatory electrocardiography in detecting maximal ventricular ectopy. Continuous 48 hour study of patients with coronary heart disease and normal subjects

1 reference

12 December 2020

Clinical pharmacology of propafenone

1 reference

12 December 2020

The arrhythmogenicity of antiarrhythmic agents

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12 December 2020

Pharmacokinetics of intravenous propafenone in patients with episodes of paroxysmal supraventricular tachycardia

1 reference

12 December 2020

The role of beta blocking agents as adjunct therapy to membrane stabilizing drugs in malignant ventricular arrhythmia

1 reference

12 December 2020

Propafenone therapy for ventricular tachycardia in the setting of congestive heart failure.

1 reference

12 December 2020

[Oral propafenone in resistant auricular arrhythmia]

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12 December 2020

Efficacy of oral propafenone in chronic ventricular arrhythmias: a placebo controlled cross-over exercise study

1 reference

12 December 2020

Plasma level and effectiveness of propafenone and its organ distribution (author's transl)

1 reference

12 December 2020

Clinical evaluation of new antiarrhythmic agents: experiences with propafenone

1 reference

12 December 2020

Effect of propafenone on left ventricular ejection fraction

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12 December 2020

Effect of propafenone in patients with stable ventricular arrhythmias

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12 December 2020

Propafenone for the treatment of severe ventricular arrhythmias

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12 December 2020

Influence of hepatic dysfunction on the pharmacokinetics of propafenone.

1 reference

12 December 2020

Malignant ventricular tachyarrhythmias in association with propafenone treatment

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12 December 2020

Antiarrhythmic drug classification: new science and practical applications

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12 December 2020

Lack of clinically significant beta-blocking effect of propafenone

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12 December 2020

Oral propafenone in the suppression of chronic stable ventricular arrhythmias

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12 December 2020

[Studies on the analysis of propafenone by means of internal analogue standardization (author's transl)]

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12 December 2020

[Significance of cardiac arrhythmias in the aged and their treatment with propafenone controlled by plasma level]

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12 December 2020

Propafenone for refractory ventricular arrhythmias: correlation with drug plasma levels during long-term treatment

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12 December 2020

Inhibiton of $$\dot V_{\max } $$ of the action potential by propafenone and its voltage-, time- and pH-dependence in mammalian ventricular myocardium

1 reference

12 December 2020

[Propafenon and lidoflazine in chronic atrial fibrillation and flutter (author's transl)]

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12 December 2020

Treatment of recurrent ventricular tachycardias using oral propafenone

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12 December 2020

The metabolic fate of 2H-labelled propafenone in man

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12 December 2020

[Therapy of ventricular arrhythmias with propafenone]

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12 December 2020

[Propafenon and alcohol: effect of this combination of behavioral performance and the subjective condition in healthy volunteers]

1 reference

12 December 2020

Effect of propafenone in the Wolff-Parkinson-White syndrome: electrophysiologic findings and long-term follow-up

1 reference

12 December 2020

Beta-blocking and electrophysiological effects of propafenone in volunteers

1 reference

12 December 2020

Evaluation of the asthmogenicity of propafenone, a new antiarrhythmic drug. Comparison of spirometry with methacholine challenge

1 reference

12 December 2020

[Antiarrhythmic efficacy of mexiletine, propafenone and flecainide in ventricular premature beats. A comparative study in patients after myocardial infarction (author's transl)]

1 reference

12 December 2020

Propafenone for the treatment of refractory complex ventricular ectopic activity

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12 December 2020

[Comparative study of the efficacy of propafenone and amiodarone in the treatment of chronic ventricular extrasystole]

1 reference

12 December 2020

A controlled trial of propafenone for treatment of frequent and repetitive ventricular premature complexes

1 reference

12 December 2020

Fatal ventricular tachycardia in association with propafenone, a new class IC antiarrhythmic agent

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12 December 2020

Binding of antiarrhythmic drugs to purified human alpha 1-acid glycoprotein.

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12 December 2020

Pharmacological studies on propafenone and its main metabolite 5-hydroxypropafenone.

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12 December 2020

Propafenone: noninvasive evaluation of efficacy

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12 December 2020

Propafenone treatment of recurrent ventricular tachycardia: comparison of continuous electrocardiographic recording and electrophysiologic study in predicting drug efficacy

1 reference

12 December 2020

[Comparative studies of tocainide and propafenone in the treatment of ventricular arrhythmias]

1 reference

12 December 2020

A case of mania secondary to propafenone

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12 December 2020

Flecainide: its proarrhythmic effect and expected changes on the surface electrocardiogram

1 reference

12 December 2020

Efficacy of propafenone compared with quinidine in chronic ventricular arrhythmias

1 reference

12 December 2020

Effects of propafenone on TEA-induced action potentials in vascular smooth muscle of canine coronary arteries

1 reference

12 December 2020

Clinical efficacy and electrophysiology of oral propafenone for ventricular tachycardia

1 reference

12 December 2020

Propafenon and propranolol in the management of cardiac extrasystoles (author's transl)

1 reference

12 December 2020

Lidocaine, mexiletine and propafenone in the treatment of arrhythmias complicating myocardial infarction. A case report.

1 reference

12 December 2020

High-performance liquid chromatographic analysis of propafenone in human plasma samples

1 reference

12 December 2020

An experimental approach to the choice of antiarrhythmic therapy.

1 reference

12 December 2020

Investigations on the pharmacokinetics of propafenone in man

1 reference

12 December 2020

10.2165/00003495-198734060-00001

Identifiers

DOI

1 reference

PubMed ID

3322781

Dimensions Publication ID

14 September 2017

0 references

1 reference

PubMed ID

3322781