(Q39691093)

English

Programmed cell death 4 (PDCD4) enhances the sensitivity of gastric cancer cells to TRAIL-induced apoptosis by inhibiting the PI3K/Akt signaling pathway

scientific article published on June 2010

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Programmed cell death 4 (PDCD4) enhances the sensitivity of gastric cancer cells to TRAIL-induced apoptosis by inhibiting the PI3K/Akt signaling pathway (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

author name string

Wei-Qiang Wang

1

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Europe PubMed Central

PubMed publication ID

14 September 2017

Hao Zhang

2

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Europe PubMed Central

PubMed publication ID

14 September 2017

Hong-Bin Wang

3

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Yong-Gang Sun

4

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Zhi-Hong Peng

5

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Gang Zhou

6

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Shi-Ming Yang

7

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Rong-Quan Wang

8

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Dian-Chun Fang

9

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14 September 2017

language of work or name

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publication date

1 June 2010

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14 September 2017

Molecular Diagnosis and Therapy

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Europe PubMed Central

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14 September 2017

14

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Europe PubMed Central

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14 September 2017

3

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14 September 2017

155-161

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PubMed publication ID

14 September 2017

https://scigraph.springernature.com/pub.10.1007/bf03256368

0 references

TRAIL and its receptors as targets for cancer therapy

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

TRAIL and cancer therapy.

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

Cell surface Death Receptor signaling in normal and cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

Translational regulation of TRAIL sensitivity.

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

Safety and antitumor activity of recombinant soluble Apo2 ligand

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

Epidermal expression of the translation inhibitor programmed cell death 4 suppresses tumorigenesis.

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

Translational regulation of autoimmune inflammation and lymphoma genesis by programmed cell death 4

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

Tumorigenesis suppressor Pdcd4 down-regulates mitogen-activated protein kinase kinase kinase kinase 1 expression to suppress colon carcinoma cell invasion

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

Differentially expressed protein Pdcd4 inhibits tumor promoter-induced neoplastic transformation

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

A novel transformation suppressor, Pdcd4, inhibits AP-1 transactivation but not NF-kappaB or ODC transactivation

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

Pdcd4 suppresses tumor phenotype in JB6 cells by inhibiting AP-1 transactivation.

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

Programmed cell death protein 4 suppresses CDK1/cdc2 via induction of p21(Waf1/Cip1)

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

Involvement of programmed cell death 4 in transforming growth factor-beta1-induced apoptosis in human hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

Loss of PDCD4 expression in human lung cancer correlates with tumour progression and prognosis

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

Pdcd4 inhibits growth of tumor cells by suppression of carbonic anhydrase type II.

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

Aerosol delivery of urocanic acid-modified chitosan/programmed cell death 4 complex regulated apoptosis, cell cycle, and angiogenesis in lungs of K-ras null mice

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

Constitutively active Akt is an important regulator of TRAIL sensitivity in prostate cancer

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

Pro-survival function of Akt/protein kinase B in prostate cancer cells. Relationship with TRAIL resistance

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

Malignant ascites protect against TRAIL-induced apoptosis by activating the PI3K/Akt pathway in human ovarian carcinoma cells

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

Akt activation by growth factors is a multiple-step process: the role of the PH domain

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

Akt phosphorylates and regulates Pdcd4 tumor suppressor protein

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

Targeting the PI3K-Akt pathway in human cancer: rationale and promise

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

AKT plays a central role in tumorigenesis

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

The protein kinase B/Akt signalling pathway in human malignancy

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

PI3 kinase/Akt signaling mediates epithelial-mesenchymal transition in hypoxic hepatocellular carcinoma cells

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

Dysregulated PI3K/Akt/PTEN pathway is a marker of a short disease-free survival in node-negative breast carcinoma

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

RNAi Codex: a portal/database for short-hairpin RNA (shRNA) gene-silencing constructs

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

Akt phosphorylation associates with LOH of PTEN and leads to chemoresistance for gastric cancer

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

Significance of Akt phosphorylation on tumor growth and vascular endothelial growth factor expression in human gastric carcinoma

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

2-Methoxyestradiol attenuates phosphatidylinositol 3-kinase/Akt pathway-mediated metastasis of gastric cancer.

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

The phosphoinositide 3-kinase pathway

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

Translation inhibitor Pdcd4 is targeted for degradation during tumor promotion

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

Programmed cell death-4 tumor suppressor protein contributes to retinoic acid-induced terminal granulocytic differentiation of human myeloid leukemia cells.

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

Suppression of programmed cell death 4 (PDCD4) protein expression by BCR-ABL-regulated engagement of the mTOR/p70 S6 kinase pathway

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

Knockdown of Pdcd4 results in induction of proprotein convertase 1/3 and potent secretion of chromogranin A and secretogranin II in a neuroendocrine cell line

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

Statin-dependent suppression of the Akt/mammalian target of rapamycin signaling cascade and programmed cell death 4 up-regulation in renal cell carcinoma

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

PI3K/Akt is involved in bufalin-induced apoptosis in gastric cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FBF03256368

21 January 2018

Frequent loss of PDCD4 expression in human glioma: possible role in the tumorigenesis of glioma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20560677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of programmed cell death 4 in multiple human cancers reveals a novel enhancer of drug sensitivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20560677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TRAIL: a molecule with multiple receptors and control mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/20560677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of programmed cell death 4 expression marks adenoma-carcinoma transition, correlates inversely with phosphorylated protein kinase B, and is an independent prognostic factor in resected colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20560677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced TRAIL sensitivity by p53 overexpression in human cancer but not normal cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/20560677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upregulated Akt signaling adjacent to gastric cancers: implications for screening and chemoprevention

1 reference

https://pubmed.ncbi.nlm.nih.gov/20560677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular determinants of response to TRAIL in killing of normal and cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20560677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor-related apoptosis-inducing ligand in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/20560677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF03256368

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

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