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English
Off-target effects related to the phosphorothioate modification of nucleic acids.
scientific article published on August 2010
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20544786
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20544786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
title
Off-target effects related to the phosphorothioate modification of nucleic acids
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20544786
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20544786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
author
Johannes Winkler
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20544786
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20544786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
author name string
Martina Stessl
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20544786
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20544786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
Jennifer Amartey
series ordinal
3
1 reference
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Europe PubMed Central
PubMed publication ID
20544786
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20544786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
Christian R Noe
series ordinal
4
1 reference
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Europe PubMed Central
PubMed publication ID
20544786
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20544786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
publication date
1 August 2010
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20544786
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20544786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
published in
ChemMedChem
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20544786
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20544786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
volume
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20544786
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20544786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
issue
8
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20544786
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20544786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
page(s)
1344-1352
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20544786
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20544786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
cites work
A proteomic study reveals unspecific apoptosis induction and reduction of glycolytic enzymes by the phosphorothioate antisense oligonucleotide oblimersen in human melanoma cells.
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7 January 2021
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Bcl-2 antisense (oblimersen sodium) plus dacarbazine in patients with advanced melanoma: the Oblimersen Melanoma Study Group
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Bcl-2 antisense in the treatment of human malignancies: a delusion in targeted therapy
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7 January 2021
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Gene profiling study of G3139- and Bcl-2-targeting siRNAs identifies a unique G3139 molecular signature
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7 January 2021
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CpG motifs in bacterial DNA and their immune effects
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7 January 2021
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G3139, an anti-Bcl-2 antisense oligomer that binds heparin-binding growth factors and collagen I, alters in vitro endothelial cell growth and tubular morphogenesis
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7 January 2021
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Specific VDAC inhibitors: phosphorothioate oligonucleotides
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7 January 2021
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Phosphorothioate oligonucleotides block the VDAC channel
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7 January 2021
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2'-O-Lysylaminohexyl oligonucleotides: modifications for antisense and siRNA.
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7 January 2021
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A randomised, controlled, double blind, escalating dose study of alicaforsen enema in active ulcerative colitis
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7 January 2021
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Intercellular adhesion molecule-1 (ICAM-1) in ulcerative colitis: presence, visualization, and significance
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7 January 2021
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Small interfering RNAs containing full 2'-O-methylribonucleotide-modified sense strands display Argonaute2/eIF2C2-dependent activity
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7 January 2021
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G3139 and other CpG-containing immunostimulatory phosphorothioate oligodeoxynucleotides are potent suppressors of the growth of human tumor xenografts in nude mice
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7 January 2021
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Antisense inhibition of ICAM-1 expression as therapy provides insight into basic inflammatory pathways through early experiences in IBD
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7 January 2021
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Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state
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Evidence of galectin-1 involvement in glioma chemoresistance
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Structure-activity relationship studies on the immune stimulatory effects of base-modified CpG toll-like receptor 9 agonists
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Innate sensing of self and non-self RNAs by Toll-like receptors
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STRING 8--a global view on proteins and their functional interactions in 630 organisms
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A pharmacologic target of G3139 in melanoma cells may be the mitochondrial VDAC.
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Lactate Dehydrogenase 5 Expression in Operable Colorectal Cancer: Strong Association With Survival and Activated Vascular Endothelial Growth Factor Pathway—A Report of the Tumour Angiogenesis Research Group
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Oligonucleotide-polyamine conjugates: influence of length and position of 2'-attached polyamines on duplex stability and antisense effect
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A novel concept for ligand attachment to oligonucleotides via a 2'-succinyl linker.
1 reference
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Crossref
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https://api.crossref.org/works/10.1002%2FCMDC.201000156
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1002/CMDC.201000156
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20544786
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20544786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
PubMed publication ID
20544786
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20544786
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20544786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
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