(Q39705925)

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Ascorbate/menadione-induced oxidative stress kills cancer cells that express normal or mutated forms of the oncogenic protein Bcr-Abl. An in vitro and in vivo mechanistic study

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Ascorbate/menadione-induced oxidative stress kills cancer cells that express normal or mutated forms of the oncogenic protein Bcr-Abl. An in vitro and in vivo mechanistic study (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

11

object named as

Julien Verrax

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

6

object named as

Bernard Gallez

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Philippe Levêque

5

object named as

Philippe Levêque

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

author name string

Raphaël Beck

1

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Rozangela Curi Pedrosa

2

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Nicolas Dejeans

3

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Christophe Glorieux

4

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Henryk Taper

7

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Stéphane Eeckhoudt

8

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Laurent Knoops

9

1 reference

Europe PubMed Central

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14 September 2017

Pedro Buc Calderon

10

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Europe PubMed Central

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14 September 2017

publication date

8 May 2010

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Europe PubMed Central

PubMed publication ID

14 September 2017

Investigational New Drugs

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Europe PubMed Central

PubMed publication ID

14 September 2017

29

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Europe PubMed Central

PubMed publication ID

14 September 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

891-900

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Reactive oxygen species in oncogenic transformation

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9441-3

21 January 2018

The signaling mechanism of ROS in tumor progression

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9441-3

21 January 2018

Antioxidant enzyme activities in normal and transformed mouse liver cells

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9441-3

21 January 2018

Ascorbate potentiates the cytotoxicity of menadione leading to an oxidative stress that kills cancer cells by a non-apoptotic caspase-3 independent form of cell death

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9441-3

21 January 2018

Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9441-3

21 January 2018

Involvement of reactive oxygen species in adaphostin-induced cytotoxicity in human leukemia cells

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9441-3

21 January 2018

The association of vitamins C and K3 kills cancer cells mainly by autoschizis, a novel form of cell death. Basis for their potential use as coadjuvants in anticancer therapy

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9441-3

21 January 2018

Enhancement of quinone redox cycling by ascorbate induces a caspase-3 independent cell death in human leukaemia cells. An in vitro comparative study

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9441-3

21 January 2018

Oxidative stress by ascorbate/menadione association kills K562 human chronic myelogenous leukaemia cells and inhibits its tumour growth in nude mice.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9441-3

21 January 2018

Endoplasmic reticulum calcium release potentiates the ER stress and cell death caused by an oxidative stress in MCF-7 cells.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9441-3

21 January 2018

Hsp90 cleavage by an oxidative stress leads to its client proteins degradation and cancer cell death.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9441-3

21 January 2018

In situ modulation of oxidative stress: a novel and efficient strategy to kill cancer cells.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9441-3

21 January 2018

Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9441-3

21 January 2018

Acute leukaemia in bcr/abl transgenic mice

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9441-3

21 January 2018

Induction of a chronic myelogenous leukemia-like syndrome in mice with v-abl and BCR/ABL.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9441-3

21 January 2018

Tyrosine kinase activity and transformation potency of bcr-abl oncogene products.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9441-3

21 January 2018

Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9441-3

21 January 2018

Instability of BCR-ABL gene in primary and cultured chronic myeloid leukemia stem cells.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9441-3

21 January 2018

Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9441-3

21 January 2018

Tissue fractionation studies. 17. Intracellular distribution of monoamine oxidase, aspartate aminotransferase, alanine aminotransferase, D-amino acid oxidase and catalase in rat-liver tissue

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9441-3

21 January 2018

Activity of the farnesyl protein transferase inhibitor SCH66336 against BCR/ABL-induced murine leukemia and primary cells from patients with chronic myeloid leukemia

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9441-3

21 January 2018

Intact human erythrocytes prevent hydrogen peroxide-mediated damage to isolated perfused rat lungs and cultured bovine pulmonary artery endothelial cells

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9441-3

21 January 2018

Erythrocyte catalase. A somatic oxidant defense?

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9441-3

21 January 2018

Human red cells scavenge extracellular hydrogen peroxide and inhibit formation of hypochlorous acid and hydroxyl radical

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9441-3

21 January 2018

Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9441-3

21 January 2018

Menadione reduction by pharmacological doses of ascorbate induces an oxidative stress that kills breast cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9441-3

21 January 2018

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9441-3

21 January 2018

Redox-directed cancer therapeutics: molecular mechanisms and opportunities

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9441-3

21 January 2018

bcr-abl, the hallmark of chronic myeloid leukaemia in man, induces multiple haemopoietic neoplasms in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20454833

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia: As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/20454833

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of glycolysis inhibition and poly(ADP-ribose) polymerase activation in necrotic-like cell death caused by ascorbate/menadione-induced oxidative stress in K562 human chronic myelogenous leukemic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20454833

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The heat shock protein 90 antagonist geldanamycin alters chaperone association with p210bcr-abl and v-src proteins before their degradation by the proteasome

1 reference

https://pubmed.ncbi.nlm.nih.gov/20454833

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The SH2 domain of P210BCR/ABL is not required for the transformation of hematopoietic factor-dependent cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20454833

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S10637-010-9441-3

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

ResearchGate publication ID

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