(Q39714436)

14 September 2017

Mutations driving CLL and their evolution in progression and relapse (English)

1 reference

14 September 2017

23

Stacey Gabriel

1 reference

14 September 2017

24

Eric S Lander

1 reference

14 September 2017

30

Stephan Stilgenbauer

0 references

Johannes G Reiter

Johannes G Reiter

5

0 references

Mara Rosenberg

Mara Rosenberg

15

0 references

Daniel Mertens

Daniel Mertens

13

0 references

Ivana Bozic

Ivana Bozic

8

0 references

Hartmut Döhner

26

Hartmut Döhner

1 reference

14 September 2017

27

Michael Hallek

1 reference

14 September 2017

29

Gad Getz

1 reference

14 September 2017

1

Dan A Landau

1 reference

14 September 2017

25

Martin A Nowak

1 reference

14 September 2017

6

Jasmin Bahlo

1 reference

14 September 2017

4

Chip Stewart

1 reference

14 September 2017

28

Donna Neuberg

1 reference

14 September 2017

Eugen Tausch

2

1 reference

14 September 2017

Amaro N Taylor-Weiner

3

1 reference

14 September 2017

Sandra Kluth

7

1 reference

14 September 2017

Mike Lawrence

9

1 reference

14 September 2017

Sebastian Böttcher

10

1 reference

14 September 2017

Scott L Carter

11

1 reference

14 September 2017

Kristian Cibulskis

12

1 reference

14 September 2017

Carrie L Sougnez

14

1 reference

14 September 2017

Julian M Hess

16

1 reference

14 September 2017

Jennifer Edelmann

17

1 reference

14 September 2017

Sabrina Kless

18

1 reference

14 September 2017

Michael Kneba

19

1 reference

14 September 2017

Matthias Ritgen

20

1 reference

14 September 2017

Anna Fink

21

1 reference

14 September 2017

Kirsten Fischer

22

1 reference

14 September 2017

Catherine J Wu

31

1 reference

14 September 2017

language of work or name

English

0 references

publication date

14 October 2015

1 reference

14 September 2017

1 reference

14 September 2017

526

1 reference

14 September 2017

525-530

1 reference

14 September 2017

7574

1 reference

https://scigraph.springernature.com/pub.10.1038/nature15395

14 September 2017

0 references

cites work

Chronic lymphocytic leukemia: 2015 Update on diagnosis, risk stratification, and treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

Tumor evolutionary directed graphs and the history of chronic lymphocytic leukemia

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

Integrated genomic characterization of papillary thyroid carcinoma

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

Critical role of SHP2 (PTPN11) signaling in germinal center-derived lymphoma

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

Acquired initiating mutations in early hematopoietic cells of CLL patients

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

Discovery and saturation analysis of cancer genes across 21 tumour types

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

Clinical and biological implications of driver mutations in myelodysplastic syndromes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

Signatures of mutational processes in human cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

Mutational heterogeneity in cancer and the search for new cancer-associated genes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

Chronic lymphocytic leukemia: molecular heterogeneity revealed by high-throughput genomics

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

14 September 2017

Cancer genome landscapes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

Evolution and impact of subclonal mutations in chronic lymphocytic leukemia

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

Integrated mutational and cytogenetic analysis identifies new prognostic subgroups in chronic lymphocytic leukemia

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

Far upstream element binding protein 1: a commander of transcription, translation and beyond

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

Monitoring chronic lymphocytic leukemia progression by whole genome sequencing reveals heterogeneous clonal evolution patterns

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

Absolute quantification of somatic DNA alterations in human cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

BRAF mutations in hairy-cell leukemia

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

Addition of rituximab to fludarabine and cyclophosphamide in patients with chronic lymphocytic leukaemia: a randomised, open-label, phase 3 trial

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

Accumulation of driver and passenger mutations during tumor progression

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

Dyrk1A phosphorylates p53 and inhibits proliferation of embryonic neuronal cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

RG7204 (PLX4032), a selective BRAFV600E inhibitor, displays potent antitumor activity in preclinical melanoma models

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

Ribosomal protein L5 and L11 mutations are associated with cleft palate and abnormal thumbs in Diamond-Blackfan anemia patients

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

Dissection of transcriptional programmes in response to serum and c-Myc in a human B-cell line.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

The role of chromosomal instability in tumor initiation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

Genetic imbalances in progressed B-cell chronic lymphocytic leukemia and transformed large-cell lymphoma (Richter's syndrome)

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

Low frequency mutations independently predict poor treatment-free survival in early stage chronic lymphocytic leukemia and monoclonal B-cell lymphocytosis.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

Gene mutations and treatment outcome in chronic lymphocytic leukemia: results from the CLL8 trial.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

The evolutionary biography of chronic lymphocytic leukemia

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

Genome-wide identification of Ikaros targets elucidates its contribution to mouse B-cell lineage specification and pre-B-cell differentiation

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

BRAF mutations in chronic lymphocytic leukemia

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

MGA, a suppressor of MYC, is recurrently inactivated in high risk chronic lymphocytic leukemia

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

ELF4/MEF activates MDM2 expression and blocks oncogene-induced p16 activation to promote transformation

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4815041

High-resolution genomic profiling of chronic lymphocytic leukemia reveals new recurrent genomic alterations

20 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE15395

Deregulation of Aiolos expression in chronic lymphocytic leukemia is associated with epigenetic modifications

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE15395

The IKZF3 (Aiolos) transcription factor is highly upregulated and inversely correlated with clinical progression in chronic lymphocytic leukaemia

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26466571

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE15395

1 reference

release_zgoexq2cgjhrxaf2qpcbljkr2e

14 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/zgoexq2cgjhrxaf2qpcbljkr2e

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

14 September 2017

1 reference