(Q39719008)

English

c-Abl and Arg are activated in human primary melanomas, promote melanoma cell invasion via distinct pathways, and drive metastatic progression

scientific article published on 5 September 2011

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

c-Abl and Arg are activated in human primary melanomas, promote melanoma cell invasion via distinct pathways, and drive metastatic progression (English)

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

author name string

S S Ganguly

1

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

L S Fiore

2

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

J T Sims

3

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

J W Friend

4

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

D Srinivasan

5

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

M A Thacker

6

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

M L Cibull

7

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

C Wang

8

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

M Novak

9

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

D M Kaetzel

10

1 reference

Europe PubMed Central

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14 September 2017

R Plattner

11

1 reference

Europe PubMed Central

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14 September 2017

language of work or name

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publication date

5 September 2011

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Europe PubMed Central

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14 September 2017

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

31

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

14

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

1804-1816

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Abl interconnects oncogenic Met and p53 core pathways in cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

An EGFR-Src-Arg-cortactin pathway mediates functional maturation of invadopodia and breast cancer cell invasion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

Molecular pathogenesis of sporadic melanoma and melanoma-initiating cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

The Cain and Abl of epithelial-mesenchymal transition and transforming growth factor-β in mammary epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

Abl kinases are required for invadopodia formation and chemokine-induced invasion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

The Role of B-RAF Mutations in Melanoma and the Induction of EMT via Dysregulation of the NF-κB/Snail/RKIP/PTEN Circuit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

B-RAF inhibitors: an evolving role in the therapy of malignant melanoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

c-Abl and Arg tyrosine kinases regulate lysosomal degradation of the oncoprotein Galectin-3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

Advances in treatment of chronic myelogenous leukemia--new treatment options with tyrosine kinase inhibitors

1 reference

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14 September 2017

Anal mucosal melanoma with KIT-activating mutation and response to imatinib therapy--case report and review of the literature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

Treatment for metastatic malignant melanoma: old drugs and new strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

A matrix metalloproteinase-1/protease activated receptor-1 signaling axis promotes melanoma invasion and metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

Activated Abl kinase inhibits oncogenic transforming growth factor-beta signaling and tumorigenesis in mammary tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

Matrix metalloproteinases: evolution, gene regulation and functional analysis in mouse models.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

Genetic subgrouping of melanoma reveals new opportunities for targeted therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

Reciprocal regulation of Abl and receptor tyrosine kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

Melanoma epidemiology and public health.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

Overexpression of the KIT/SCF in uveal melanoma does not translate into clinical efficacy of imatinib mesylate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

Abl kinases regulate autophagy by promoting the trafficking and function of lysosomal components

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

Cytoplasmic signalling by the c-Abl tyrosine kinase in normal and cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

Activated c-Abl tyrosine kinase in malignant solid tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

Oncogenic activation of c-Abl in non-small cell lung cancer cells lacking FUS1 expression: inhibition of c-Abl by the tumor suppressor gene product Fus1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

Revealing the genomic heterogeneity of melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

Targeting STAT3 affects melanoma on multiple fronts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

Lack of clinical efficacy of imatinib in metastatic melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

A clinical and biological overview of gastrointestinal stromal tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

Determinants of BRAF mutations in primary melanomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

Interstitial collagenases as markers of tumor progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

c-Abl is activated by growth factors and Src family kinases and has a role in the cellular response to PDGF

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

A study of tumor progression: the precursor lesions of superficial spreading and nodular melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

Evidence for regulation of the human ABL tyrosine kinase by a cellular inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

Aggressive breast cancer cells are dependent on activated Abl kinases for proliferation, anchorage-independent growth and survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

MDA-MB-435 cells are derived from M14 melanoma cells--a loss for breast cancer, but a boon for melanoma research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

The EphB4 receptor suppresses breast cancer cell tumorigenicity through an Abl-Crk pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

Activation of Abl tyrosine kinases promotes invasion of aggressive breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

Antiproliferative effect of STI571 on cultured human cutaneous melanoma-derived cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

Cell density-dependent regulation of matrix metalloproteinase and TIMP expression in differently tumorigenic breast cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

14 September 2017

Signal transducer and activator of transcription 3 activation promotes invasive growth of colon carcinomas through matrix metalloproteinase induction

1 reference

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17 June 2018

Nanoneoadjuvant therapy of gastrointestinal stromal tumor (GIST).

1 reference

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20 August 2018

Improving chemotherapeutic drug penetration in melanoma by imatinib mesylate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

20 August 2018

A critical role for cortactin phosphorylation by Abl-family kinases in PDGF-induced dorsal-wave formation

1 reference

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20 August 2018

Requirement of STAT3 activation for maximal collagenase-1 (MMP-1) induction by epidermal growth factor and malignant characteristics in T24 bladder cancer cells.

1 reference

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20 August 2018

Expression of tyrosine kinases in human malignancies as potential targets for kinase-specific inhibitors

1 reference

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20 August 2018

Imatinib mesylate in cutaneous melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235241

20 August 2018

Pharmacokinetics and cellular uptake of imatinib and its main metabolite CGP74588.

1 reference

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20 August 2018

The Ets-1 and Ets-2 transcription factors activate the promoters for invasion-associated urokinase and collagenase genes in response to epidermal growth factor

1 reference

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20 August 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.361

31 March 2020

Quantitative cell dispersion analysis: new test to measure tumor cell aggressiveness

1 reference

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31 March 2020

A new link between the c-Abl tyrosine kinase and phosphoinositide signalling through PLC-gamma1

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31 March 2020

Identifiers

10.1038/ONC.2011.361

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

ResearchGate publication ID

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