(Q39720687)

14 September 2017

title

TRAIL signaling is mediated by DR4 in pancreatic tumor cells despite the expression of functional DR5. (English)

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Anna Trauzold

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author name string

Johannes Lemke

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Andreas Noack

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Vladimir Tchikov

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Uwe Bertsch

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Christian Röder

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Stefan Schütze

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Holger Kalthoff

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publication date

31 March 2010

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Journal of Molecular Medicine

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published in

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volume

88

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issue

7

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page(s)

729-740

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https://scigraph.springernature.com/pub.10.1007/s00109-010-0619-0

14 September 2017

exact match

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cites work

Resistance to TRAIL-induced apoptosis in primitive neuroectodermal brain tumor cells correlates with a loss of caspase-8 expression.

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12 December 2020

Mutations of tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1) and receptor 2 (TRAIL-R2) genes in metastatic breast cancers

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12 December 2020

Emerging non-apoptotic functions of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)/Apo2L.

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12 December 2020

The receptor for the cytotoxic ligand TRAIL

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12 December 2020

Trail receptors: targets for cancer therapy

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12 December 2020

Activation of protein kinase C inhibits TRAIL-induced caspases activation, mitochondrial events and apoptosis in a human leukemic T cell line

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12 December 2020

Receptor-selective mutants of apoptosis-inducing ligand 2/tumor necrosis factor-related apoptosis-inducing ligand reveal a greater contribution of death receptor (DR) 5 than DR4 to apoptosis signaling

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12 December 2020

TRICK2, a new alternatively spliced receptor that transduces the cytotoxic signal from TRAIL

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12 December 2020

Bcl-XL protects pancreatic adenocarcinoma cells against CD95- and TRAIL-receptor-mediated apoptosis

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12 December 2020

TRAIL signalling: decisions between life and death.

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12 December 2020

CD95 and TRAF2 promote invasiveness of pancreatic cancer cells.

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12 December 2020

Chronic lymphocytic leukemic cells exhibit apoptotic signaling via TRAIL-R1.

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12 December 2020

Protein kinase C modulates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by targeting the apical events of death receptor signaling

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12 December 2020

TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL.

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12 December 2020

Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2.

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12 December 2020

The promoter of human p22/PACAP response gene 1 (PRG1) contains functional binding sites for the p53 tumor suppressor and for NFkappaB.

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12 December 2020

Role of caspases in CD95L- and TRAIL-induced non-apoptotic signalling in pancreatic tumour cells

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12 December 2020

TRAIL promotes metastasis of human pancreatic ductal adenocarcinoma

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12 December 2020

Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer

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12 December 2020

FLICE is predominantly expressed as two functionally active isoforms, caspase-8/a and caspase-8/b.

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12 December 2020

Bortezomib sensitizes primary human astrocytoma cells of WHO grades I to IV for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis.

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12 December 2020

Is TRAIL the holy grail of cancer therapy?

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12 December 2020

Characterization of two receptors for TRAIL

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12 December 2020

CD95 and TRAIL receptor-mediated activation of protein kinase C and NF-kappaB contributes to apoptosis resistance in ductal pancreatic adenocarcinoma cells

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12 December 2020

Tumor-derived mutations in the TRAIL receptor DR5 inhibit TRAIL signaling through the DR4 receptor by competing for ligand binding

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12 December 2020

Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

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12 December 2020

Protein kinase C inhibition and x-linked inhibitor of apoptosis protein degradation contribute to the sensitization effect of luteolin on tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in cancer cells

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12 December 2020

Compartmentalization of TNF receptor 1 signaling: internalized TNF receptosomes as death signaling vesicles

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12 December 2020

Multiple and synergistic deregulations of apoptosis-controlling genes in pancreatic carcinoma cells

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12 December 2020

Differential activation of TRAIL-R1 and -2 by soluble and membrane TRAIL allows selective surface antigen-directed activation of TRAIL-R2 by a soluble TRAIL derivative

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12 December 2020

Inactivating mutations of KILLER/DR5 gene in gastric cancers

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12 December 2020

Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL.

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12 December 2020

Nonapoptotic functions of FADD-binding death receptors and their signaling molecules

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12 December 2020

An antagonist decoy receptor and a death domain-containing receptor for TRAIL

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12 December 2020

Induction of apoptosis by monoclonal antibody anti-APO-1 class switch variants is dependent on cross-linking of APO-1 cell surface antigens

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12 December 2020

10.1007/S00109-010-0619-0

Identifiers

DOI

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14 September 2017

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