(Q39729002)

14 September 2017

Role of the locus and of the resistance gene on gene amplification frequency in methotrexate resistant Leishmania tarentolae (English)

1 reference

14 September 2017

1 reference

Kündig C

1

1 reference

14 September 2017

Leblanc E

series ordinal

2

1 reference

14 September 2017

Papadopoulou B

series ordinal

3

1 reference

14 September 2017

Ouellette M

series ordinal

4

1 reference

14 September 2017

language of work or name

English

0 references

publication date

1 September 1999

1 reference

14 September 2017

Nucleic Acids Research

1 reference

14 September 2017

27

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14 September 2017

18

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14 September 2017

3653-3659

1 reference

Gene amplification in Leishmania

14 September 2017

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F27.18.3653

Drug resistance and P-glycoprotein gene amplification in the protozoan parasite Leishmania

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F27.18.3653

Overproduction of a bifunctional thymidylate synthetase-dihydrofolate reductase and DNA amplification in methotrexate-resistant Leishmania tropica

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F27.18.3653

Unstable DNA amplifications in methotrexate-resistant Leishmania consist of extrachromosomal circles which relocalize during stabilization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F27.18.3653

PTR1: a reductase mediating salvage of oxidized pteridines and methotrexate resistance in the protozoan parasite Leishmania major.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F27.18.3653

Pterin and folate reduction by the Leishmania tarentolae H locus short-chain dehydrogenase/reductase PTR1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F27.18.3653

The roles of pteridine reductase 1 and dihydrofolate reductase-thymidylate synthase in pteridine metabolism in the protozoan parasite Leishmania major

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F27.18.3653

Residues involved in co-factor and substrate binding of the short-chain dehydrogenase/reductase PTR1 producing methotrexate resistance in Leishmania.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F27.18.3653

A pteridine reductase gene ptr1 contiguous to a P-glycoprotein confers resistance to antifolates in Trypanosoma cruzi.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F27.18.3653

Frequent amplification of a short chain dehydrogenase gene as part of circular and linear amplicons in methotrexate resistant Leishmania

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F27.18.3653

P-glycoprotein overexpression in methotrexate-resistant Leishmania tropica

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F27.18.3653

Increased transport of pteridines compensates for mutations in the high affinity folate transporter and contributes to methotrexate resistance in the protozoan parasite Leishmania tarentolae

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F27.18.3653

Formation of extrachromosomal circular amplicons with direct or inverted duplications in drug-resistant Leishmania tarentolae

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F27.18.3653

Linear amplicons as precursors of amplified circles in methotrexate-resistant Leishmania tarentolae

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F27.18.3653

Homologous recombination between direct repeat sequences yields P-glycoprotein containing amplicons in arsenite resistant Leishmania

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F27.18.3653

Folate utilisation by Leishmania species and the identification of intracellular derivatives and folate-metabolising enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F27.18.3653

New mechanisms of drug resistance in parasitic protozoa

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F27.18.3653

Co-existence of circular and multiple linear amplicons in methotrexate-resistant Leishmania

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F27.18.3653

21 January 2018

Identifiers

DOI

10.1093/NAR/27.18.3653

1 reference

14 September 2017

1 reference

14 September 2017

PubMed publication ID

10471733

1 reference