(Q39731986)

14 September 2017

The evolutionarily conserved interaction between LC3 and p62 selectively mediates autophagy-dependent degradation of mutant huntingtin (English)

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14 September 2017

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Ying-Tsen Tung

1

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14 September 2017

Wen-Ming Hsu

2

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14 September 2017

Hsinyu Lee

3

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14 September 2017

Wei-Pang Huang

4

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14 September 2017

Yung-Feng Liao

5

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14 September 2017

5 March 2010

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Cellular and Molecular Neurobiology

14 September 2017

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14 September 2017

30

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14 September 2017

5

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14 September 2017

795-806

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https://scigraph.springernature.com/pub.10.1007/s10571-010-9507-y

14 September 2017

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cites work

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The selectivity of autophagy and its role in cell death and survival

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Cvt19 is a receptor for the cytoplasm-to-vacuole targeting pathway.

21 January 2018

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12 December 2020

Autophagy: from phenomenology to molecular understanding in less than a decade

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12 December 2020

Expression of ubiquitin-binding protein p62 in ubiquitin-immunoreactive intraneuronal inclusions in amyotrophic lateral sclerosis with dementia: analysis of five autopsy cases with broad clinicopathological spectrum

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12 December 2020

Mutation at the cargo-receptor binding site of Atg8 also affects its general autophagy regulation function

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12 December 2020

Ubiquitin-binding protein p62 is present in neuronal and glial inclusions in human tauopathies and synucleinopathies

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12 December 2020

The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway

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12 December 2020

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

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12 December 2020

Atg19 mediates a dual interaction cargo sorting mechanism in selective autophagy

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12 December 2020

Two newly identified sites in the ubiquitin-like protein Atg8 are essential for autophagy

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12 December 2020

Mutant ubiquitin and p62 immunoreactivity in cases of combined multiple system atrophy and Alzheimer's disease.

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12 December 2020

Ubiquitin/proteasome pathway regulates levels of retinoic acid receptor gamma and retinoid X receptor alpha in human keratinocytes

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12 December 2020

Human light chain 3/MAP1LC3B is cleaved at its carboxyl-terminal Met121 to expose Gly120 for lipidation and targeting to autophagosomal membranes

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12 December 2020

Dynamics and diversity in autophagy mechanisms: lessons from yeast

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12 December 2020

Dissection of autophagosome biogenesis into distinct nucleation and expansion steps

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12 December 2020

Structure and functional properties of the ubiquitin binding protein p62

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12 December 2020

α-Synuclein Is Degraded by Both Autophagy and the Proteasome

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12 December 2020

Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast

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12 December 2020

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

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12 December 2020

Increased expression of p62 in expanded polyglutamine-expressing cells and its association with polyglutamine inclusions.

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12 December 2020

A ubiquitin-like system mediates protein lipidation

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12 December 2020

Interaction of protein kinase C zeta with ZIP, a novel protein kinase C-binding protein

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12 December 2020

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

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12 December 2020

Proteases acting on mutant huntingtin generate cleaved products that differentially build up cytoplasmic and nuclear inclusions

1 reference

12 December 2020

The crystal structure of microtubule-associated protein light chain 3, a mammalian homologue of Saccharomyces cerevisiae Atg8.

1 reference

12 December 2020

Atg8, a ubiquitin-like protein required for autophagosome formation, mediates membrane tethering and hemifusion

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12 December 2020

A Unified Nomenclature for Yeast Autophagy-Related Genes

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12 December 2020

A picky eater: exploring the mechanisms of selective autophagy in human pathologies

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12 December 2020

Major histocompatibility complex class II-restricted presentation of a cytosolic antigen by autophagy

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12 December 2020

Autophagic-lysosomal perturbation enhances tau aggregation in transfectants with induced wild-type tau expression

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12 December 2020

Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation

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12 December 2020

Membrane recruitment of Aut7p in the autophagy and cytoplasm to vacuole targeting pathways requires Aut1p, Aut2p, and the autophagy conjugation complex

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12 December 2020

Microtubules facilitate autophagosome formation and fusion of autophagosomes with endosomes

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12 December 2020

Toxic proteins in neurodegenerative disease

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12 December 2020

cAMP-response element-binding protein contributes to suppression of the A2A adenosine receptor promoter by mutant Huntingtin with expanded polyglutamine residues

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12 December 2020

Ubiquitin recognition by the ubiquitin-associated domain of p62 involves a novel conformational switch

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12 December 2020

Structural basis of target recognition by Atg8/LC3 during selective autophagy

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12 December 2020

Autophagy inhibition compromises degradation of ubiquitin-proteasome pathway substrates.

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12 December 2020

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

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12 December 2020

New insights into the mechanisms of macroautophagy in mammalian cells

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12 December 2020

Development by self-digestion: molecular mechanisms and biological functions of autophagy

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12 December 2020

The N-terminus and Phe52 residue of LC3 recruit p62/SQSTM1 into autophagosomes

1 reference

12 December 2020

Structural basis for sorting mechanism of p62 in selective autophagy

1 reference

12 December 2020

10.1007/S10571-010-9507-Y

Identifiers

DOI

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14 September 2017

1 reference