(Q39732586)

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Targeting PKC delta-mediated topoisomerase II beta overexpression subverts the differentiation block in a retinoic acid-resistant APL cell line

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Europe PubMed Central

PubMed publication ID

14 September 2017

Targeting PKC delta-mediated topoisomerase II beta overexpression subverts the differentiation block in a retinoic acid-resistant APL cell line (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

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S McNamara

1

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

J N Nichol

2

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

H Wang

3

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Europe PubMed Central

PubMed publication ID

14 September 2017

W H Miller

4

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Europe PubMed Central

PubMed publication ID

14 September 2017

publication date

4 March 2010

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Europe PubMed Central

PubMed publication ID

14 September 2017

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Europe PubMed Central

PubMed publication ID

14 September 2017

24

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Europe PubMed Central

PubMed publication ID

14 September 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

729-739

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

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Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

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Induction of retinoid resistance by all-trans retinoic acid in acute promyelocytic leukemia after remission

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Frequent mutations in the ligand-binding domain of PML-RARalpha after multiple relapses of acute promyelocytic leukemia: analysis for functional relationship to response to all-trans retinoic acid and histone deacetylase inhibitors in vitro and in v

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Topoisomerase IIbeta negatively modulates retinoic acid receptor alpha function: a novel mechanism of retinoic acid resistance

1 reference

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Eukaryotic DNA topoisomerase II beta

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Late formation and prolonged differentiation of the Moon inferred from W isotopes in lunar metals

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Topoisomerase II binds importin alpha isoforms and exportin/CRM1 but does not shuttle between the nucleus and cytoplasm in proliferating cells.

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A novel arsenical has antitumor activity toward As2O3-resistant and MRP1/ABCC1-overexpressing cell lines

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Protein kinase C delta activates topoisomerase IIalpha to induce apoptotic cell death in response to DNA damage

1 reference

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Activation of protein kinase C delta by all-trans-retinoic acid

1 reference

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Retinoic acid mediates degradation of IRS-1 by the ubiquitin-proteasome pathway, via a PKC-dependant mechanism

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Rottlerin, a novel protein kinase inhibitor

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Regulation of phospholipid scramblase activity during apoptosis and cell activation by protein kinase Cdelta

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Protein kinase Cdelta mediates retinoic acid and phorbol myristate acetate-induced phospholipid scramblase 1 gene expression: its role in leukemic cell differentiation

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Role of protein kinase C-delta (PKC-delta) in the generation of the effects of IFN-alpha in chronic myelogenous leukemia cells

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Inhibition of protein kinase C delta has negative effect on anchorage-independent growth of BCR-ABL-transformed Rat1 cells

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The PKC delta inhibitor, rottlerin, induces apoptosis of haematopoietic cell lines through mitochondrial membrane depolarization and caspases' cascade

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Specificity and mechanism of action of some commonly used protein kinase inhibitors

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Phosphorylation of DNA topoisomerase II by casein kinase II: modulation of eukaryotic topoisomerase II activity in vitro

1 reference

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Casein kinase I delta/epsilon phosphorylates topoisomerase IIalpha at serine-1106 and modulates DNA cleavage activity

1 reference

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Plk1-dependent phosphorylation regulates functions of DNA topoisomerase IIalpha in cell cycle progression.

1 reference

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Phosphorylation of serine 1106 in the catalytic domain of topoisomerase II alpha regulates enzymatic activity and drug sensitivity

1 reference

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Jun NH2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress.

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Importance of MEK-1/-2 signaling in monocytic and granulocytic differentiation of myeloid cell lines

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Activation of Rac1 and the p38 mitogen-activated protein kinase pathway in response to all-trans-retinoic acid

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Epidermal growth factor-dependent cyclooxygenase-2 induction in gliomas requires protein kinase C-delta

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Identification of new classes among acute myelogenous leukaemias with normal karyotype using gene expression profiling.

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Gene expression profiling of B lymphocytes and plasma cells from Waldenström's macroglobulinemia: comparison with expression patterns of the same cell counterparts from chronic lymphocytic leukemia, multiple myeloma and normal individuals

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Modulation of DNA topoisomerase II activity and expression in melanoma cells with acquired drug resistance

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RAR agonists stimulate SOX9 gene expression in breast cancer cell lines: evidence for a role in retinoid-mediated growth inhibition

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C/EBPbeta: a major PML-RARA-responsive gene in retinoic acid-induced differentiation of APL cells.

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Antiproliferative actions of insulin-like growth factor binding protein (IGFBP)-3 in human breast cancer cells.

1 reference

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Defect in the regulation of 4E-BP1 and 2, two repressors of translation initiation, in the retinoid acid resistant cell lines, NB4-R1 and NB4-R2.

1 reference

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21 January 2018

A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors

1 reference

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Molecular interaction of retinoic acid receptors with coregulators PCAF and RIP140.

1 reference

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The Ski protein can inhibit ligand induced RARalpha and HDAC3 degradation in the retinoic acid signaling pathway

1 reference

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Structural basis for gate-DNA recognition and bending by type IIA topoisomerases

1 reference

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DNA topoisomerases: essential enzymes and lethal targets

1 reference

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Effect of 5-aza-2'-deoxycytidine and retinoic acid on differentiation and c-myc expression in HL-60 myeloid leukemic cells

1 reference

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Isoform specificity of activators and inhibitors of protein kinase C gamma and delta

1 reference

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Rottlerin, a PKC isozyme-selective inhibitor, affects signaling events and cytokine production in human monocytes

1 reference

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Phosphorylation of the alpha- and beta-isoforms of DNA topoisomerase II is qualitatively different in interphase and mitosis in Chinese hamster ovary cells

1 reference

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Altered drug interaction and regulation of topoisomerase IIbeta: potential mechanisms governing sensitivity of HL-60 cells to amsacrine and etoposide.

1 reference

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Direct interaction of all-trans-retinoic acid with protein kinase C (PKC). Implications for PKC signaling and cancer therapy

1 reference

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Topoisomerase IIalpha gene amplification and response to anthracycline-containing adjuvant chemotherapy in breast cancer

1 reference

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based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/LEU.2010.27

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

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