(Q39748795)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27206843%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

title

A role for amyloid precursor protein translation to restore iron homeostasis and ameliorate lead (Pb) neurotoxicity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27206843%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27206843%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

author name string

Vivek Venkataramani

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27206843%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Cecilia Washburn

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27206843%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Yanyan Liu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27206843%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Vinusha Tummala

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27206843%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Hong Jiang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27206843%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Ann Smith

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27206843%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Catherine M Cahill

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27206843%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

language of work or name

English

0 references

publication date

1 August 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27206843%20AND%20SRC:MED&resulttype=core&format=json

Journal of Neurochemistry

2 April 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27206843%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

volume

138

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27206843%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27206843%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

page(s)

479-494

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27206843%20AND%20SRC:MED&resulttype=core&format=json

An in vitro model for neuroscience: differentiation of SH-SY5Y cells into cells with morphological and biochemical characteristics of mature neurons

2 April 2020

cites work

1 reference

Biosynthesis of heme in mammals

21 January 2018

1 reference

The IRP1-HIF-2α axis coordinates iron and oxygen sensing with erythropoiesis and iron absorption

21 January 2018

1 reference

Exposure to As-, Cd-, and Pb-mixture induces Aβ, amyloidogenic APP processing and cognitive impairments via oxidative stress-dependent neuroinflammation in young rats

21 January 2018

1 reference

Parkinson's disease iron deposition caused by nitric oxide-induced loss of β-amyloid precursor protein.

21 January 2018

1 reference

Alzheimer's disease therapeutics targeted to the control of amyloid precursor protein translation: maintenance of brain iron homeostasis

21 January 2018

1 reference

Role of the APP non-amyloidogenic signaling pathway and targeting alpha-secretase as an alternative drug target for treatment of Alzheimer's disease.

21 January 2018

1 reference

Novel 5' untranslated region directed blockers of iron-regulatory protein-1 dependent amyloid precursor protein translation: implications for down syndrome and Alzheimer's disease

21 January 2018

1 reference

The fetal basis of amyloidogenesis: exposure to lead and latent overexpression of amyloid precursor protein and beta-amyloid in the aging brain.

21 January 2018

1 reference

Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease

21 January 2018

1 reference

Infantile exposure to lead and late-age cognitive decline: relevance to AD.

21 January 2018

1 reference

Chelators as antidotes of metal toxicity: therapeutic and experimental aspects

21 January 2018

1 reference

Divalent metal transporter 1 in lead and cadmium transport

21 January 2018

1 reference

Iron acquired from transferrin by K562 cells is delivered into a cytoplasmic pool of chelatable iron(II).

21 January 2018

1 reference

Iron is essential for neuron development and memory function in mouse hippocampus

21 January 2018

1 reference

Decreased brain volume in adults with childhood lead exposure

21 January 2018

1 reference

Proton magnetic resonance spectroscopy in adults with childhood lead exposure

21 January 2018

1 reference

Selective translational control of the Alzheimer amyloid precursor protein transcript by iron regulatory protein-1.

21 January 2018

1 reference

Iron regulatory protein-1 protects against mitoferrin-1-deficient porphyria

21 January 2018

1 reference

Manganese targets m-aconitase and activates iron regulatory protein 2 in AF5 GABAergic cells

21 January 2018

1 reference

Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease

21 January 2018

1 reference

Optimising parameters for the differentiation of SH-SY5Y cells to study cell adhesion and cell migration

21 January 2018

1 reference

Ferritin expression in rat hepatocytes and Kupffer cells after lead nitrate treatment

21 January 2018

1 reference

Multiple determinants within iron-responsive elements dictate iron regulatory protein binding and regulatory hierarchy

21 January 2018

1 reference

Lead exposure increases levels of β-amyloid in the brain and CSF and inhibits LRP1 expression in APP transgenic mice

21 January 2018

1 reference

Iron-dependent regulation of the divalent metal ion transporter

21 January 2018

1 reference

Iron regulates the intracellular degradation of iron regulatory protein 2 by the proteasome

21 January 2018

1 reference

Mechanisms of neuroprotection by hemopexin: modeling the control of heme and iron homeostasis in brain neurons in inflammatory states

21 January 2018

1 reference

Elevated Blood Lead Levels in Children Associated With the Flint Drinking Water Crisis: A Spatial Analysis of Risk and Public Health Response

21 January 2018

1 reference

Persistent increase of blood lead level and suppression of δ-ALAD activity in northern bobwhite quail orally dosed with even a single 2-mm spent lead shot.

21 January 2018

1 reference

Lead poisoning and chelation in a mother-neonate pair

21 January 2018

1 reference

Hemopexin in the human retina: protection of the retina against heme-mediated toxicity

21 January 2018

1 reference

Intrahippocampal administration of lead (Pb) impairs performance of rats in the Morris water maze.

21 January 2018

1 reference

Soluble amyloid beta-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration

21 January 2018

1 reference

Direct Fe2+ sensing by iron-responsive messenger RNA:repressor complexes weakens binding

21 January 2018

1 reference

Rapid kinetics of iron responsive element (IRE) RNA/iron regulatory protein 1 and IRE-RNA/eIF4F complexes respond differently to metal ions

21 January 2018

1 reference

Low-level lead exposure and autistic behaviors in school-age children

21 January 2018

1 reference

Interactions between iron deficiency and lead poisoning: epidemiology and pathogenesis

21 January 2018

1 reference

The LEARn model: an epigenetic explanation for idiopathic neurobiological diseases.

21 January 2018

1 reference

Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export.

21 January 2018

1 reference

Derepression of ferritin messenger RNA translation by hemin in vitro

21 January 2018

1 reference

Lead exposure induced microgliosis and astrogliosis in hippocampus of young mice potentially by triggering TLR4-MyD88-NFκB signaling cascades

21 January 2018

1 reference

Nutritional Factors and Susceptibility to Lead Toxicity

21 January 2018

1 reference

Zinc and cadmium specifically interfere with RNA-binding activity of human iron regulatory protein 1.

21 January 2018

1 reference

Distribution system water age can create premise plumbing corrosion hotspots

21 January 2018

1 reference

Inherent variability in lead and copper collected during standardized sampling

21 January 2018

1 reference

Mechanistic analysis of iron accumulation by endothelial cells of the BBB

21 January 2018

1 reference

sAPP modulates iron efflux from brain microvascular endothelial cells by stabilizing the ferrous iron exporter ferroportin

21 January 2018

1 reference

Mechanisms of brain iron transport: insight into neurodegeneration and CNS disorders.

21 January 2018

1 reference

Influence of HFE variants and cellular iron on monocyte chemoattractant protein-1.

21 January 2018

1 reference

Ingestion of Mn and Pb by rats during and after pregnancy alters iron metabolism and behavior in offspring

21 January 2018

1 reference

Red cells, hemoglobin, heme, iron, and atherogenesis

21 January 2018

1 reference

21 January 2018

1 reference

Effect of estradiol on heme biosynthetic pathway in lead-poisoned rabbits

21 January 2018

1 reference

Neurotoxicity and aggressiveness triggered by low-level lead in children: a review

21 January 2018

1 reference

Early postnatal lead exposure induces tau phosphorylation in the brain of young rats

21 January 2018

1 reference

Exposure to As, Cd and Pb-mixture impairs myelin and axon development in rat brain, optic nerve and retina

21 January 2018

1 reference

Reduction of iron-regulated amyloid precursor protein and beta-amyloid peptide by (-)-epigallocatechin-3-gallate in cell cultures: implications for iron chelation in Alzheimer's disease

21 January 2018

1 reference

Metal and inflammatory targets for Alzheimer's disease

21 January 2018

1 reference

Translation of the alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5'-untranslated region sequences.

21 January 2018

1 reference

An iron-responsive element type II in the 5'-untranslated region of the Alzheimer's amyloid precursor protein transcript

21 January 2018

1 reference

21 January 2018

Brain iron metabolism

1 reference

Regulation and gene expression of heme synthesis under heavy metal exposure--review

21 January 2018

1 reference

Ferroportin deficiency impairs manganese metabolism in flatiron mice

21 January 2018

1 reference

Iron depletion increases manganese uptake and potentiates apoptosis through ER stress

21 January 2018

1 reference

Cumulative lead dose and cognitive function in adults: a review of studies that measured both blood lead and bone lead

21 January 2018

1 reference

Succimer chelation improves learning, attention, and arousal regulation in lead-exposed rats but produces lasting cognitive impairment in the absence of lead exposure.

21 January 2018

1 reference

Acute and longer term effects of meso-2,3 dimercaptosuccinic acid (DMSA) on the behavior of lead-exposed and control mice.

21 January 2018

1 reference

Does the calcein-AM method assay the total cellular 'labile iron pool' or only a fraction of it?

21 January 2018

1 reference

Iron-regulatory proteins, iron-responsive elements and ferritin mRNA translation

21 January 2018

1 reference

Thyrotropin-releasing hormone and epidermal growth factor regulate iron-regulatory protein binding in pituitary cells via protein kinase C-dependent and -independent signaling pathways

21 January 2018

1 reference

The acute box cis-element in human heavy ferritin mRNA 5'-untranslated region is a unique translation enhancer that binds poly(C)-binding proteins

21 January 2018

1 reference

Description of 3,180 courses of chelation with dimercaptosuccinic acid in children ≤ 5 y with severe lead poisoning in Zamfara, Northern Nigeria: a retrospective analysis of programme data

21 January 2018

1 reference

The up-regulation of ferritin expression using a small-molecule ligand to the native mRNA

21 January 2018

1 reference

Histone deacetylase inhibitor valproic acid inhibits cancer cell proliferation via down-regulation of the alzheimer amyloid precursor protein

21 January 2018

1 reference

Amyloid precursor protein is a biomarker for transformed human pluripotent stem cells.

21 January 2018

1 reference

Aluminium and lead: molecular mechanisms of brain toxicity

21 January 2018

1 reference

Structure of dual function iron regulatory protein 1 complexed with ferritin IRE-RNA

21 January 2018

1 reference

Regulation of cellular iron metabolism

21 January 2018

1 reference

Excess capacity of the iron regulatory protein system

21 January 2018

1 reference

Lead induces dysregulation of iron regulatory protein 1 via the extracellular signal-regulated kinase pathway in human vascular endothelial cells

21 January 2018

1 reference

Novel dose-dependent alterations in excitatory GABA during embryonic development associated with lead (Pb) neurotoxicity

21 January 2018

1 reference

β-Amyloid precursor protein does not possess ferroxidase activity but does stabilize the cell surface ferrous iron exporter ferroportin

21 January 2018

1 reference

Post-transcriptional modulation of iron homeostasis during p53-dependent growth arrest

21 January 2018

1 reference

Lead-induced iron overload and attenuated effects of ferroportin 1 overexpression in PC12 cells.

21 January 2018

1 reference

The effect of lead exposure on brain iron homeostasis and the expression of DMT1/FP1 in the brain in developing and aged rats

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/JNC.13671

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27206843%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1 reference