(Q33796184)

English

Histone deacetylase inhibitor valproic acid inhibits cancer cell proliferation via down-regulation of the alzheimer amyloid precursor protein

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scholarly article

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Europe PubMed Central

PubMed publication ID

29 July 2017

Histone deacetylase inhibitor valproic acid inhibits cancer cell proliferation via down-regulation of the alzheimer amyloid precursor protein (English)

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Europe PubMed Central

PubMed publication ID

29 July 2017

Alzheimer's disease

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Christian Rossner

2

object named as

Christian Rossner

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Europe PubMed Central

PubMed publication ID

29 July 2017

author name string

Vivek Venkataramani

1

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Europe PubMed Central

PubMed publication ID

29 July 2017

Lara Iffland

3

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Europe PubMed Central

PubMed publication ID

29 July 2017

Stefan Schweyer

4

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Irfan Y Tamboli

5

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Jochen Walter

6

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Oliver Wirths

7

1 reference

Europe PubMed Central

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29 July 2017

Thomas A Bayer

8

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Europe PubMed Central

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29 July 2017

language of work or name

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publication date

9 February 2010

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Europe PubMed Central

PubMed publication ID

29 July 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

29 July 2017

285

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Europe PubMed Central

PubMed publication ID

29 July 2017

14

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

10678-10689

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2856276/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Cancer linked to Alzheimer disease but not vascular dementia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Transcriptional induction of GRP78/BiP by histone deacetylase inhibitors and resistance to histone deacetylase inhibitor-induced apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Neuroprotective secreted amyloid precursor protein acts by disrupting amyloid precursor protein dimers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Neprilysin gene expression requires binding of the amyloid precursor protein intracellular domain to its promoter: implications for Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Valproic acid inhibits Abeta production, neuritic plaque formation, and behavioral deficits in Alzheimer's disease mouse models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

HDAC family: What are the cancer relevant targets?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Amyloid precursor protein trafficking, processing, and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

A closer look at alpha-secretase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Valproic acid as epigenetic cancer drug: preclinical, clinical and transcriptional effects on solid tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

A critical function for beta-amyloid precursor protein in neuronal migration revealed by in utero RNA interference

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

The in vivo brain interactome of the amyloid precursor protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

The relevance of estrogen receptor-beta expression to the antiproliferative effects observed with histone deacetylase inhibitors and phytoestrogens in prostate cancer treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Current Insights into Molecular Mechanisms of Alzheimer Disease and Their Implications for Therapeutic Approaches

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Induction of GRP78 by valproic acid is dependent upon histone deacetylase inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Role for histone deacetylase 1 in human tumor cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Altered cholesterol metabolism in APP695-transfected neuroblastoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Teratogenesis of sodium valproate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Expression of neutral endopeptidase (NEP/CD10) on pancreatic tumor cell lines, pancreatitis and pancreatic tumor tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Valproic acid induces apoptosis, p16INK4A upregulation and sensitization to chemotherapy in human melanoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Endoplasmic reticulum chaperones inhibit the production of amyloid-beta peptides.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

The amyloid precursor protein: beyond amyloid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Gene silencing analyses against amyloid precursor protein (APP) gene family by RNA interference

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Valproic acid inhibits invasiveness in bladder cancer but not in prostate cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Chronic administration of valproic acid inhibits prostate cancer cell growth in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Altered localization of amyloid precursor protein under endoplasmic reticulum stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Antineoplastic effects of the DNA methylation inhibitor hydralazine and the histone deacetylase inhibitor valproic acid in cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Inhibition of glycosphingolipid biosynthesis reduces secretion of the beta-amyloid precursor protein and amyloid beta-peptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Effects of the histone deacetylase inhibitor valproic acid on Notch signalling in human neuroblastoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Evolving anticancer drug valproic acid: insights into the mechanism and clinical studies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Increased expression of amyloid precursor protein in oral squamous cell carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Inhibition of histone deacetylase activity by valproic acid blocks adipogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Amyloid precursor protein mediates proinflammatory activation of monocytic lineage cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

The history of valproate in clinical neuroscience

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Increased expression and processing of the Alzheimer amyloid precursor protein in pancreatic cancer may influence cellular proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Histone deacetylases (HDACs): characterization of the classical HDAC family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Anti-tumor mechanisms of valproate: a novel role for an old drug

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

The search for alpha-secretase and its potential as a therapeutic approach to Alzheimer s disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Amyloid beta protein precursor is involved in the growth of human colon carcinoma cell in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Alzheimer's disease: genes, proteins, and therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

A possible role for the Alzheimer amyloid precursor protein in the regulation of epidermal basal cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Key factors in Alzheimer's disease: beta-amyloid precursor protein processing, metabolism and intraneuronal transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

The Hallmarks of Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

It all sticks together--the APP-related family of proteins and Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Glucose regulation of GRP78 gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

The regulation of amyloid precursor protein metabolism by cholinergic mechanisms and neurotrophin receptor signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

The chaperone BiP/GRP78 binds to amyloid precursor protein and decreases Abeta40 and Abeta42 secretion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

From differentiation to proliferation: the secretory amyloid precursor protein as a local mediator of growth in thyroid epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Amyloid beta-protein and the genetics of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Regulation of amyloid protein precursor (APP) binding to collagen and mapping of the binding sites on APP and collagen type I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Amino acid sequence RERMS represents the active domain of amyloid beta/A4 protein precursor that promotes fibroblast growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid beta protein precursor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Peptides containing the RERMS sequence of amyloid beta/A4 protein precursor bind cell surface and promote neurite extension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Increase of synaptic density and memory retention by a peptide representing the trophic domain of the amyloid beta/A4 protein precursor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Amyloid-like properties of peptides flanking the epitope of amyloid precursor protein-specific monoclonal antibody 22C11.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Nerve growth factor increases mRNA levels for the prion protein and the beta-amyloid protein precursor in developing hamster brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Secreted form of amyloid beta protein precursor is involved in the growth regulation of fibroblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Beta-amyloid precursor protein cleavage by a membrane-bound protease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Membrane inserted APP fragments containing the beta A4 sequence of Alzheimer's disease do not aggregate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

4 July 2018

Sodium valproate inhibits in vivo growth of human neuroblastoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

28 July 2018

Amyloid precursor protein is a primary androgen target gene that promotes prostate cancer growth.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.057836

21 January 2018

Copper inhibits beta-amyloid production and stimulates the non-amyloidogenic pathway of amyloid-precursor-protein secretion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.057836

21 January 2018

Transient intraneuronal A beta rather than extracellular plaque pathology correlates with neuron loss in the frontal cortex of APP/PS1KI mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.057836

21 January 2018

High sensitivity to carcinogens in the brain of a mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.057836

21 January 2018

Induction of terminal differentiation in melanoma cells on downregulation of beta-amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.057836

21 January 2018

Nerve growth factor modulates the expression and secretion of beta-amyloid precursor protein through different mechanisms in PC12 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.057836

21 January 2018

Soluble form of amyloid precursor protein regulates proliferation of progenitors in the adult subventricular zone.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.057836

21 January 2018

The survival of rat cerebral cortical neurons in the presence of trophic APP peptides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.057836

21 January 2018

Histone deacetylase is a target of valproic acid-mediated cellular differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.057836

21 January 2018

Role of Class I and Class II histone deacetylases in carcinoma cells using siRNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.057836

21 January 2018

Drug-induced inactivation or gene silencing of class I histone deacetylases suppresses ovarian cancer cell growth: implications for therapy.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.057836

21 January 2018

HDAC inhibitors: magic bullets, dirty drugs or just another targeted therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.057836

21 January 2018

Neurite-outgrowth regulating functions of the amyloid protein precursor of Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

30 October 2018

Valproic acid inhibits proliferation and changes expression of CD44 and CD56 of malignant glioma cells in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856276

30 October 2018

Differential display PCR reveals novel targets for the mood-stabilizing drug valproate including the molecular chaperone GRP78

1 reference

https://pubmed.ncbi.nlm.nih.gov/20145244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of Alzheimer's amyloid precursor protein (APP) by secretases occurs after O-glycosylation of APP in the protein secretory pathway. Identification of intracellular compartments in which APP cleavage occurs without using toxic agents that int

1 reference

https://pubmed.ncbi.nlm.nih.gov/20145244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor signaling is up-regulated in human colonic aberrant crypt foci

1 reference

https://pubmed.ncbi.nlm.nih.gov/20145244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Level and function of epidermal growth factor receptor predict the metastatic potential of human colon carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20145244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of beta-amyloid precursor protein isoform mRNAs by bFGF in astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20145244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological evaluation of various metabolites and analogues of valproic acid. Anticonvulsant and toxic potencies in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20145244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A gene trap insertion reveals that amyloid precursor protein expression is a very early event in murine embryogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20145244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M109.057836

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

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