(Q39755067)

English

Inhibition of secretion of interleukin (IL)-12/IL-23 family cytokines by 4-trifluoromethyl-celecoxib is coupled to degradation via the endoplasmic reticulum stress protein HERP.

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scholarly article

1 reference

Europe PubMed Central

14 September 2017

Inhibition of secretion of interleukin (IL)-12/IL-23 family cytokines by 4-trifluoromethyl-celecoxib is coupled to degradation via the endoplasmic reticulum stress protein HERP. (English)

1 reference

Europe PubMed Central

14 September 2017

endoplasmic reticulum

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author name string

Martin McLaughlin

1

1 reference

Europe PubMed Central

14 September 2017

Iraide Alloza

2

1 reference

Europe PubMed Central

14 September 2017

Hung Pham Quoc

3

1 reference

Europe PubMed Central

14 September 2017

Christopher J Scott

4

1 reference

Europe PubMed Central

14 September 2017

Yasuhiko Hirabayashi

5

1 reference

Europe PubMed Central

14 September 2017

Koen Vandenbroeck

6

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Europe PubMed Central

14 September 2017

language of work or name

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publication date

6 January 2010

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Europe PubMed Central

14 September 2017

number of pages

10

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inferred from page(s)

Journal of Biological Chemistry

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Europe PubMed Central

14 September 2017

285

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Europe PubMed Central

14 September 2017

10

1 reference

Europe PubMed Central

14 September 2017

6960-6969

1 reference

Europe PubMed Central

14 September 2017

Interleukin-35: odd one out or part of the family?

1 reference

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One step at a time: endoplasmic reticulum-associated degradation

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A rush to judgment on Th17

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IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition.

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Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)

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22 September 2017

Aggravated endoplasmic reticulum stress as a basis for enhanced glioblastoma cell killing by bortezomib in combination with celecoxib or its non-coxib analogue, 2,5-dimethyl-celecoxib

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Signalling, inflammation and arthritis: crossed signals: the role of interleukin (IL)-12, -17, -23 and -27 in autoimmunity.

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The endoplasmic reticulum and the unfolded protein response

1 reference

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Direct non-cyclooxygenase-2 targets of celecoxib and their potential relevance for cancer therapy

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Interleukin-12, interleukin-23, and psoriasis: current prospects

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Endoplasmic reticulum stress: signaling the unfolded protein response

1 reference

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22 September 2017

Calcium-activated endoplasmic reticulum stress as a major component of tumor cell death induced by 2,5-dimethyl-celecoxib, a non-coxib analogue of celecoxib.

1 reference

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The ubiquitin E3 ligase POSH regulates calcium homeostasis through spatial control of Herp

1 reference

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22 September 2017

Up-regulation of 150-kDa oxygen-regulated protein by celecoxib in human gastric carcinoma cells

1 reference

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22 September 2017

IL-12p40: an inherently agonistic cytokine

1 reference

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22 September 2017

Homocysteine regulates expression of Herp by DNA methylation involving the AARE and CREB binding sites

1 reference

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Proteomic profiling identifies cyclooxygenase-2-independent global proteomic changes by celecoxib in colorectal cancer cells.

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Luman/CREB3 induces transcription of the endoplasmic reticulum (ER) stress response protein Herp through an ER stress response element

1 reference

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Cyclooxygenase-2 (COX-2)-independent anticarcinogenic effects of selective COX-2 inhibitors

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IL-12 p80 is an innate epithelial cell effector that mediates chronic allograft dysfunction

1 reference

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22 September 2017

Celecoxib inhibits interleukin-12 alphabeta and beta2 folding and secretion by a novel COX2-independent mechanism involving chaperones of the endoplasmic reticulum.

1 reference

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22 September 2017

The ubiquitin-domain protein HERP forms a complex with components of the endoplasmic reticulum associated degradation pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844145

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The metallopeptide antibiotic bacitracin inhibits interleukin-12 alphabeta and beta2 secretion

1 reference

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Anti-interleukin-12 antibody for active Crohn's disease

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A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol

1 reference

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22 September 2017

Role of Herp in the endoplasmic reticulum stress response

1 reference

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Herp stabilizes neuronal Ca2+ homeostasis and mitochondrial function during endoplasmic reticulum stress

1 reference

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Inhibiting cytokines of the interleukin-12 family: recent advances and novel challenges.

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Cross-linking approach to affinity capture of protein complexes from chaotrope-solubilized cell lysates.

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The ubiquitin‐like domain of Herp is involved in Herp degradation, but not necessary for its enhancement of amyloid β‐protein generation

1 reference

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An optimized method for the isolation and identification of membrane proteins

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22 September 2017

The cyclo-oxygenase-2 inhibitor celecoxib perturbs intracellular calcium by inhibiting endoplasmic reticulum Ca2+-ATPases: a plausible link with its anti-tumour effect and cardiovascular risks

1 reference

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Herp, a new ubiquitin-like membrane protein induced by endoplasmic reticulum stress

1 reference

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BiP and immunoglobulin light chain cooperate to control the folding of heavy chain and ensure the fidelity of immunoglobulin assembly

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The relationship between intracellular UDP-N-acetyl hexosamine nucleotide pool and monoclonal antibody production in a mouse hybridoma.

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Assembly of immunoglobulin light chains as a prerequisite for secretion. A model for oligomerization-dependent subunit folding

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Characterization of an ERAD pathway for nonglycosylated BiP substrates, which require Herp

1 reference

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A monoclonal antibody against human homocysteine-induced endoplasmic reticulum protein (Herp): a useful tool for evaluating endoplasmic reticulum stress

1 reference

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15 June 2018

Herp is dually regulated by both the endoplasmic reticulum stress-specific branch of the unfolded protein response and a branch that is shared with other cellular stress pathways

1 reference

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IL-12 p40 homodimer-dependent macrophage chemotaxis and respiratory viral inflammation are mediated through IL-12 receptor beta 1.

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15 June 2018

Transactivation of the grp78 promoter by Ca2+ depletion. A comparative analysis with A23187 and the endoplasmic reticulum Ca(2+)-ATPase inhibitor thapsigargin

1 reference

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Celecoxib transiently inhibits cellular protein synthesis

1 reference

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Celecoxib upregulates endoplasmic reticulum chaperones that inhibit celecoxib-induced apoptosis in human gastric cells

1 reference

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20 August 2018

Identifiers

10.1074/JBC.M109.056614

1 reference

Europe PubMed Central

14 September 2017

1 reference

Europe PubMed Central

14 September 2017

1 reference

Europe PubMed Central

14 September 2017

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