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Pirh2 E3 ubiquitin ligase targets DNA polymerase eta for 20S proteasomal degradation.
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scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
2815560
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20008555%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
title
Pirh2 E3 ubiquitin ligase targets DNA polymerase eta for 20S proteasomal degradation
(English)
1 reference
stated in
Europe PubMed Central
PMCID
2815560
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20008555%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
author
Gang Liu
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
2815560
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20008555%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
author name string
Yong-Sam Jung
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
2815560
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20008555%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
Xinbin Chen
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
2815560
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20008555%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
language of work or name
English
0 references
publication date
14 December 2009
1 reference
stated in
Europe PubMed Central
PMCID
2815560
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20008555%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
published in
Molecular and Cellular Biology
1 reference
stated in
Europe PubMed Central
PMCID
2815560
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20008555%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
volume
30
1 reference
stated in
Europe PubMed Central
PMCID
2815560
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20008555%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
page(s)
1041-1048
1 reference
stated in
Europe PubMed Central
PMCID
2815560
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20008555%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
issue
4
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stated in
Europe PubMed Central
PMCID
2815560
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20008555%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
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PLAGL2 controls the stability of Pirh2, an E3 ubiquitin ligase for p53
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Phosphorylation of Pirh2 by calmodulin-dependent kinase II impairs its ability to ubiquitinate p53
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DNA polymerase eta, the product of the xeroderma pigmentosum variant gene and a target of p53, modulates the DNA damage checkpoint and p53 activation.
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Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis
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Dual roles for DNA polymerase eta in homologous DNA recombination and translesion DNA synthesis
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MDM2 is a negative regulator of p21WAF1/CIP1, independent of p53.
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Control of human PIRH2 protein stability: involvement of TIP60 and the proteosome
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22 September 2017
Protein degradation and protection against misfolded or damaged proteins
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MDM2 promotes p21waf1/cip1 proteasomal turnover independently of ubiquitylation
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22 September 2017
Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation
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The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta
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The ubiquitin system
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PubMed Central
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22 September 2017
Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
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22 September 2017
Mdm2 promotes the rapid degradation of p53
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PubMed Central
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22 September 2017
Accumulation of p53 in a mutant cell line defective in the ubiquitin pathway
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22 September 2017
Post-Translational Regulation of the 54K Cellular Tumor Antigen in Normal and Transformed Cells
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22 September 2017
A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein
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22 September 2017
Lessons from the discovery of the ubiquitin system
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retrieved
25 September 2017
Identifiers
DOI
10.1128/MCB.01198-09
1 reference
stated in
Europe PubMed Central
PMCID
2815560
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20008555%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
PMCID
2815560
1 reference
stated in
Europe PubMed Central
PMCID
2815560
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20008555%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
PubMed ID
20008555
1 reference
stated in
Europe PubMed Central
PMCID
2815560
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20008555%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
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