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Axonal transport defects are a common phenotype in Drosophila models of ALS.
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5181624
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31 March 2020
title
Axonal transport defects are a common phenotype in Drosophila models of ALS
(English)
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5181624
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31 March 2020
main subject
Drosophila
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amyotrophic lateral sclerosis
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phenotype
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author
Victoria Hewitt
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3
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5181624
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31 March 2020
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Katie R Baldwin
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1
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5181624
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31 March 2020
Vinay K Godena
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2
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5181624
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31 March 2020
Alexander J Whitworth
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4
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31 March 2020
publication date
7 April 2016
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31 March 2020
published in
Human Molecular Genetics
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5181624
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31 March 2020
volume
25
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31 March 2020
issue
12
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31 March 2020
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2378-2392
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5181624
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31 March 2020
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Deficits in axonal transport precede ALS symptoms in vivo
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22 September 2017
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TDP-43, the signature protein of FTLD-U, is a neuronal activity-responsive factor
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22 September 2017
Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content
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22 September 2017
Axonal transport of mitochondria requires milton to recruit kinesin heavy chain and is light chain independent
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22 September 2017
Polyglutamine diseases and transport problems: deadly traffic jams on neuronal highways.
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22 September 2017
Neurofilaments and orthograde transport are reduced in ventral root axons of transgenic mice that express human SOD1 with a G93A mutation
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22 September 2017
TLS (FUS) binds RNA in vivo and engages in nucleo-cytoplasmic shuttling
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22 September 2017
Imaging axonal transport of mitochondria
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25 September 2017
Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons
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17 June 2018
Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS.
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20 August 2018
Bidirectional transcripts of the expanded C9orf72 hexanucleotide repeat are translated into aggregating dipeptide repeat proteins
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20 August 2018
Dipeptide repeat protein pathology in C9ORF72 mutation cases: clinico-pathological correlations
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20 August 2018
hnRNP A3 binds to GGGGCC repeats and is a constituent of p62-positive/TDP43-negative inclusions in the hippocampus of patients with C9orf72 mutations
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20 August 2018
Depletion of TDP-43 affects Drosophila motoneurons terminal synapsis and locomotive behavior
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20 August 2018
GSK-3beta inhibition reverses axonal transport defects and behavioural phenotypes in Drosophila
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20 August 2018
Fus deficiency in mice results in defective B-lymphocyte development and activation, high levels of chromosomal instability and perinatal death.
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20 August 2018
Identifiers
DOI
10.1093/HMG/DDW105
1 reference
stated in
Europe PubMed Central
PMC publication ID
5181624
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27056981%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 March 2020
PMC publication ID
5181624
1 reference
stated in
Europe PubMed Central
PMC publication ID
5181624
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27056981%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 March 2020
PubMed publication ID
27056981
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stated in
Europe PubMed Central
PMC publication ID
5181624
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27056981%20AND%20SRC:MED&resulttype=core&format=json
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