(Q39779043)

English

Structure-activity relationships of 6-(2,6-dichlorophenyl)-8-methyl-2-(phenylamino)pyrido[2,3-d]pyrimidin-7-ones: toward selective Abl inhibitors

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Structure-activity relationships of 6-(2,6-dichlorophenyl)-8-methyl-2-(phenylamino)pyrido[2,3-d]pyrimidin-7-ones: toward selective Abl inhibitors (English)

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Christophe Antczak

1

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

author name string

Darren R Veach

2

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Christina N Ramirez

3

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Maria A Minchenko

4

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

David Shum

5

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Paul A Calder

6

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Mark G Frattini

7

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Bayard Clarkson

8

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Hakim Djaballah

9

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Europe PubMed Central

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14 September 2017

language of work or name

0 references

publication date

23 October 2009

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Bioorganic & Medicinal Chemistry Letters

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Europe PubMed Central

PMC publication ID

14 September 2017

19

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Europe PubMed Central

PMC publication ID

14 September 2017

24

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

6872-6876

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3629380

22 September 2017

Synthesis and in vitro examination of [124I]-, [125I]- and [131I]-2-(4-iodophenylamino) pyrido[2,3-d]pyrimidin-7-one radiolabeled Abl kinase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3629380

22 September 2017

PD166326, a novel tyrosine kinase inhibitor, has greater antileukemic activity than imatinib mesylate in a murine model of chronic myeloid leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3629380

22 September 2017

Chemical proteomic analysis reveals alternative modes of action for pyrido[2,3-d]pyrimidine kinase inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3629380

22 September 2017

Inhibition of wild-type and mutant Bcr-Abl by pyrido-pyrimidine-type small molecule kinase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3629380

22 September 2017

A novel pyridopyrimidine inhibitor of abl kinase is a picomolar inhibitor of Bcr-abl-driven K562 cells and is effective against STI571-resistant Bcr-abl mutants.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3629380

22 September 2017

Inhibition of Bcr-Abl kinase activity by PD180970 blocks constitutive activation of Stat5 and growth of CML cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3629380

22 September 2017

Synthesis and tyrosine kinase inhibitory activity of a series of 2-amino-8H-pyrido[2,3-d]pyrimidines: identification of potent, selective platelet-derived growth factor receptor tyrosine kinase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3629380

22 September 2017

Structure-activity relationships for a novel series of pyrido[2,3-d]pyrimidine tyrosine kinase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3629380

22 September 2017

2-Substituted aminopyrido[2,3-d]pyrimidin-7(8H)-ones. structure-activity relationships against selected tyrosine kinases and in vitro and in vivo anticancer activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3629380

15 June 2018

Characterization of potent inhibitors of the Bcr-Abl and the c-kit receptor tyrosine kinases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3629380

20 August 2018

The pyrido[2,3-d]pyrimidine derivative PD180970 inhibits p210Bcr-Abl tyrosine kinase and induces apoptosis of K562 leukemic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19889540

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical and cellular effects of c-Src kinase-selective pyrido[2, 3-d]pyrimidine tyrosine kinase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19889540

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A high density assay format for the detection of novel cytotoxic agents in large chemical libraries

1 reference

https://pubmed.ncbi.nlm.nih.gov/19889540

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.BMCL.2009.10.085

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

ResearchGate publication ID

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