(Q74271438)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10974196%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

Biochemical and cellular effects of c-Src kinase-selective pyrido[2, 3-d]pyrimidine tyrosine kinase inhibitors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10974196%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

author name string

A J Kraker

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10974196%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

B G Hartl

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10974196%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

A M Amar

3

1 reference

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9 November 2019

M R Barvian

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10974196%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

H D Showalter

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10974196%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

C W Moore

6

1 reference

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9 November 2019

language of work or name

English

0 references

publication date

1 October 2000

1 reference

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9 November 2019

published in

Biochemical Pharmacology

1 reference

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9 November 2019

volume

60

1 reference

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9 November 2019

issue

7

1 reference

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9 November 2019

page(s)

885-898

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10974196%20AND%20SRC:MED&resulttype=core&format=json

Cellular functions regulated by Src family kinases

9 November 2019

cites work

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7 January 2021

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Activating SRC mutation in a subset of advanced human colon cancers

7 January 2021

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Overexpression of c-Src in areas of hyperproliferation in head and neck cancer, premalignant lesions and benign mucosal disorders

7 January 2021

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Overexpression and activation of the tyrosine kinase Src in human pancreatic carcinoma

7 January 2021

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DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases.

7 January 2021

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Src phosphorylation of the epidermal growth factor receptor at novel sites mediates receptor interaction with Src and P85 alpha

7 January 2021

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Site-specific association of c-Src with epidermal growth factor receptor in A431 cells

7 January 2021

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A role for epidermal growth factor receptor, c-Src and focal adhesion kinase in an in vitro model for the progression of colon cancer

7 January 2021

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7 January 2021

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Regulation of vascular endothelial growth factor expression in human colon carcinoma cells by activity of src kinase

7 January 2021

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C-Src activation by ErbB2 leads to attachment-independent growth of human breast epithelial cells

7 January 2021

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A role for Src in signal relay by the platelet-derived growth factor alpha receptor

7 January 2021

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Inhibition of pp60c-Src reduces Bcl-XL expression and reverses the transformed phenotype of cells overexpressing EGF and HER-2 receptors

7 January 2021

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EGF receptor signaling stimulates SRC kinase phosphorylation of clathrin, influencing clathrin redistribution and EGF uptake.

7 January 2021

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Mechanism of biological synergy between cellular Src and epidermal growth factor receptor

7 January 2021

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c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function

7 January 2021

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Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

7 January 2021

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A novel inhibitor of the tyrosine kinase Src suppresses phosphorylation of its major cellular substrates and reduces bone resorption in vitro and in rodent models in vivo

7 January 2021

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Inhibition of p56(lck) tyrosine kinase by isothiazolones

7 January 2021

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Discovery of a novel series of potent and selective substrate-based inhibitors of p60c-src protein tyrosine kinase: conformational and topographical constraints in peptide design

7 January 2021

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Selective inhibition of Src protein tyrosine kinase by analogues of 5-S-glutathionyl-beta-alanyl-L-dopa

7 January 2021

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Benzodiazepine compounds as inhibitors of the src protein tyrosine kinase: screening of a combinatorial library of 1,4-benzodiazepines

7 January 2021

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Synthesis and tyrosine kinase inhibitory activity of a series of 2-amino-8H-pyrido[2,3-d]pyrimidines: identification of potent, selective platelet-derived growth factor receptor tyrosine kinase inhibitors

7 January 2021

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2-Substituted aminopyrido[2,3-d]pyrimidin-7(8H)-ones. structure-activity relationships against selected tyrosine kinases and in vitro and in vivo anticancer activity

7 January 2021

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Cytoskeletal and morphological changes associated with the specific suppression of the epidermal growth factor receptor tyrosine kinase activity in A431 human epidermoid carcinoma

7 January 2021

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7 January 2021

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7 January 2021

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Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

7 January 2021

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Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein

7 January 2021

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7 January 2021

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c-Src activates both STAT1 and STAT3 in PDGF-stimulated NIH3T3 cells

7 January 2021

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ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases

7 January 2021

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Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: a role for paxillin tyrosine phosphorylation

7 January 2021

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Agonist-stimulated cytoskeletal reorganization and signal transduction at focal adhesions in vascular smooth muscle cells require c-Src

7 January 2021

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7 January 2021

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7 January 2021

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Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases

7 January 2021

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p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase

7 January 2021

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Complexes of focal adhesion kinase (FAK) and Crk-associated substrate (p130(Cas)) are elevated in cytoskeleton-associated fractions following adhesion and Src transformation. Requirements for Src kinase activity and FAK proline-rich motifs

7 January 2021

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Biochemical and antiproliferative properties of 4-[ar(alk)ylamino]pyridopyrimidines, a new chemical class of potent and specific epidermal growth factor receptor tyrosine kinase inhibitor

7 January 2021

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7 January 2021

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An homogeneous assay for measuring the uptake and efflux of radiolabelled drugs in adherent cells

7 January 2021

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Requirement for Src family protein tyrosine kinases in G2 for fibroblast cell division

7 January 2021

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Small molecule inhibitors of the platelet-derived growth factor receptor, the fibroblast growth factor receptor, and Src family tyrosine kinases

7 January 2021

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Specific inhibition of epidermal growth factor receptor tyrosine kinase by 4-anilinoquinazolines

7 January 2021

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4-(Phenylamino)pyrrolopyrimidines: potent and selective, ATP site directed inhibitors of the EGF-receptor protein tyrosine kinase

7 January 2021

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Stat3 activation by Src induces specific gene regulation and is required for cell transformation

7 January 2021

1 reference

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The Src family tyrosine kinases are required for platelet-derived growth factor-mediated signal transduction in NIH 3T3 cells

7 January 2021

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Src family kinases are required for integrin but not PDGFR signal transduction.

7 January 2021

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Multiple roles for Src in a PDGF-stimulated cell

7 January 2021

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c-Src, receptor tyrosine kinases, and human cancer

7 January 2021

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

6 Statistical analysis of enzyme kinetic data

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900405-6

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0006-2952(00)00405-6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10974196%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference